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1. 急性腎障害（急性腎不全）におけるナトリウム（FENa）、尿素（FEUrea）、およびその他分子の排泄率 fractional excretion of sodium urea and other molecules in acute kidney injury acute renal failure
2. 急性腎障害（急性腎不全）における腎前性疾患および急性尿細管壊死の病因および診断 etiology and diagnosis of prerenal disease and acute tubular necrosis in acute kidney injury acute renal failure
3. 低ナトリウム血症を有する成人の評価 evaluation of adults with hyponatremia
4. 小児における急性腎障害：臨床的特徴、病因、評価、および診断 acute kidney injury in children clinical features etiology evaluation and diagnosis
5. 虚血後（虚血性）の急性尿細管壊死の発症および病因 pathogenesis and etiology of postischemic ischemic acute tubular necrosis

English Journal

The urea to creatinine ratio is predictive of worsening kidney function in ambulatory heart failure patients.

Sood MM1, Saeed M2, Lim V2, Cordova F2, Komenda P3, Malik A2, Rigatto C3, Shafer LA4, Tangri N3, Tappia PS5, Zieroth S2.
Journal of cardiac failure.J Card Fail.2015 Feb 24. pii: S1071-9164(15)00045-7. doi: 10.1016/j.cardfail.2015.02.003. [Epub ahead of print]
BACKGROUND: Changes in kidney function in heart failure patients conveys important prognostic information. We investigated the association of the urea to creatinine (UCr) ratio, the fractional excretion of urea (FeUrea) and the fractional excretion of sodium (FeNa) and subsequent declines in kidney
PMID 25724301

Urinary output and fractional excretion of sodium and urea as indicators of transient versus intrinsic acute kidney injury during early sepsis.

Vanmassenhove J, Glorieux G, Hoste E, Dhondt A, Vanholder R, Van Biesen W.
Critical care (London, England).Crit Care.2013 Oct 13;17(5):R234. doi: 10.1186/cc13057.
INTRODUCTION: The pathophysiology of acute kidney injury (AKI) in sepsis is ill defined. We investigated parameters associated with low glomerular filtration, and their predictive value to discriminate transient from intrinsic septic AKI.METHODS: In 107 sepsis patients, AKI was defined by the Risk,
PMID 24119730

Volume management in the critically ill patient with acute kidney injury.

Labib M1, Khalid R, Khan A, Khan S.
Critical care research and practice.Crit Care Res Pract.2013;2013:792830. doi: 10.1155/2013/792830. Epub 2013 Feb 7.
Acute kidney injury (AKI) frequently occurs in the setting of critical illness and its management poses a challenge for the intensivist. Optimal management of volume status is critical in the setting of AKI in the ICU patient. The use of urine sodium, the fractional excretion of sodium (FeNa), and t
PMID 23476757

Japanese Journal

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安藤明利
日本腎臓学会誌 23(10), 1373-1388, 1981
… (2) Reverse relationship was observed between FEurea and [U/P] creat and also between FEurea and T<SUB>H2</SUB> … FEurea and FE<SUB>H2</SUB>o of Papx group became significantly higher than those of pNx group. …
NAID 130004168665

Related Pictures

FENA vs (10) FEUrea Amazon.com: Feurea: Pita` Kusho: MP3 The Kidney Doctor : September 2012 Excretion Urea (FEUrea) • Medfixation hyponatremia use of fena and feurea and The following online medical calculations

★リンクテーブル★

リンク元	「腎前性腎不全」「尿素窒素排泄率」

「腎前性腎不全」

　　[★]

英: prerenal failure
関: 肝腎症候群、腎不全、急性腎不全

病因

体液量減少

消化管からの体液喪失
腎性喪失：利尿薬、尿細管障害、アジソン病など
出血
third spaceへの喪失
有効循環血液量の減少

低血圧

敗血症
心原性ショック
アナフイラキシー
麻酔および薬物誘発性
自動調節能レベル以下の相対的低血圧：平均血圧で80mmHg未満

腎の血行動態変化

診断

利尿薬を使用していない患者の腎前性腎不全の診断

考える技術第2版 p.529

	腎前性腎不全	腎性腎不全 (急性尿細管壊死)	利尿薬を使用していない腎前性腎不全の診断に関する検査特性
	腎前性腎不全	腎性腎不全 (急性尿細管壊死)	感度(%)	特異度(%)	陽性尤度比	陰性尤度比
尿Na (mEq/L)	＜20	＞20	90	82	5	0.12
FENa (%)	＜1	＞2	96	95	19	0.04
FEurea (%)	＜35	＞50	90	96	22.5	0.1

「尿素窒素排泄率」

　　[★]

英: fractional excretion of urea, FEurea, FEUrea
同: 尿中尿素窒素排泄率 urinary fractional excretion of urea
関: 尿素窒素 UN、腎前性腎不全、ナトリウム排泄率 fractional excretion of sodium FENa

概念

糸球体で濾過された尿素窒素(UN)のうち実際に尿中に排泄される尿素窒素の割合

定義

尿量(ml/hr)をVとすると

FENa = C_urea / C_Cr x 100 = (U_urea x V ) / S_urea / ( (U_Cr x V ) / S_Cr )

= U_urea / S_urea / ( U_Cr / S_Cr )

特徴