WordNet
- the 1st letter of the Roman alphabet (同)a
- the blood group whose red cells carry the A antigen (同)type_A, group A
- in the Christian era; used before dates after the supposed year Christ was born; "in AD 200" (同)A.D., anno_Domini
PrepTutorEJDIC
- Vice Admiral
- answer / ampere
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/12 22:34:49」(JST)
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- 1. 成人における皮膚筋炎および多発性筋炎の臨床症状 clinical manifestations of dermatomyositis and polymyositis in adults
- 2. 皮膚筋炎の初期マネージメント initial management of cutaneous dermatomyositis
- 3. 皮膚筋炎および多発性筋炎における間質性肺疾患：臨床症状および診断 interstitial lung disease in dermatomyositis and polymyositis clinical manifestations and diagnosis
- 4. 成人における皮膚筋炎および多発性筋炎の診断および鑑別診断 diagnosis and differential diagnosis of dermatomyositis and polymyositis in adults
- 5. 皮膚筋炎および多発性筋炎における間質性肺疾患：治療 interstitial lung disease in dermatomyositis and polymyositis treatment
English Journal
- Immediate breast reconstruction with acellular dermal matrix: Factors affecting outcome.
- Lardi AM1, Ho-Asjoe M2, Mohanna PN2, Farhadi J3.
- Journal of plastic, reconstructive & aesthetic surgery : JPRAS.J Plast Reconstr Aesthet Surg.2014 Aug;67(8):1098-105. doi: 10.1016/j.bjps.2014.05.020. Epub 2014 May 20.
- BACKGROUND: The use of acellular dermal matrix (ADM) for coverage of the lower pole in immediate implant-based breast reconstruction has changed surgeons' practice. We present our experience using a porcine ADM (Strattice), focusing on short-term outcomes, patient selection, and technique adaptation
- PMID 24927863
- Validity and reliability of VO2-max measurements in persons with multiple sclerosis.
- Langeskov-Christensen M1, Langeskov-Christensen D2, Overgaard K2, Møller AB3, Dalgas U2.
- Journal of the neurological sciences.J Neurol Sci.2014 Jul 15;342(1-2):79-87. doi: 10.1016/j.jns.2014.04.028. Epub 2014 Apr 27.
- BACKGROUND: Direct measurement of whole body maximal oxygen consumption (VO2-max test) is considered the gold standard when assessing cardiorespiratory fitness. Nonetheless, the validity and reliability of the test have not been examined in persons with multiple sclerosis (PwMS).OBJECTIVE: To invest
- PMID 24825731
- A Multi-state Study on Mental Health Evaluation for Children Entering Foster Care.
- Hayek M1, Mackie TI, Mulé CM, Bellonci C, Hyde J, Bakan JS, Leslie LK.
- Administration and policy in mental health.Adm Policy Ment Health.2014 Jul;41(4):552-67. doi: 10.1007/s10488-013-0495-3.
- When compared with the general United States child population, children entering foster care have elevated rates of mental health problems. This study examines: (1) state approaches to mental health evaluations for children entering foster care for the first time, (2) the consistency of these approa
- PMID 23709285
Japanese Journal
- Excitability of the Primary Motor Cortex Increases More Strongly with Slow- than with Normal-Speed Presentation of Actions
- Moriuchi Takefumi,Iso Naoki,Sagari Akira,Ogahara Kakuya,Kitajima Eiji,Tanaka Koji,Tabira Takayuki,Higashi Toshio
- PLoS ONE 9(12), e114355, 2014-12-05
- … MEPs were recorded from the thenar (TH) and abductor digiti minimi (ADM) muscles of the right hand.Results: The MEP amplitudes were higher when the subjects watched the video clip at low speed than when they watched the clip at normal speed. … ADM, normal vs. half; … and ADM, normal vs. quarter. … ADM, "catch" higher than "open" at half speed.Conclusions: These results indicate that the excitability of M1 was higher when the observed action was played at low speed. …
- NAID 120005526599
- 41092 幼稚園・保育所における冬季室内環境とインフルエンザ対策に関する研究 : 岐阜地域における9の比較検討(室内温熱環境(1),環境工学II,2014年度日本建築学会大会(近畿)学術講演会・建築デザイン発表会)
- 今枝 弘貴,水谷 章夫,青木 哲
- 学術講演梗概集 2014(環境工学II), 183-184, 2014-09-12
- NAID 110009855685
- Architecture Domain Matrix手法による医用分析装置統合システムソフトウェアの開発
- 兒玉 隆一郎,島袋 潤,高木 由充,小泉 忍,田野 俊一
- 情報処理学会論文誌 55(8), 1796-1806, 2014-08-15
- … ，AIMS内に広範囲な改造が発生し開発計画が難しくなる．そこでAIMSのアーキテクチャ要素をさらに検査室の業務フロー要素単位に分解して，コア資産とアプリケーションを区分け解析するArchitecture Domain Matrix（ADM）手法を考案した．この手法により見積り時点でのコア資産開発コストを統制し，加えて，改造部位を業務フロー要素ごとにまとめるとWork Breakdown Structure（WBS）が作成でき，アーキテクチャ要素ごとに集計す …
- NAID 170000084659
Related Links
- Each day, ADM transforms crops such as corn, oilseeds, wheat and cocoa into food, feed, and agriculturally derived fuels and chemicals.
- 本社大阪市中央区。アナログIC・DSPなど電子デバイス製品の輸出入・販売。企業・IR 情報、事業・商品の紹介。
Related Pictures
★リンクテーブル★
| リンク元 | 「ドキソルビシン」「無筋炎型皮膚筋炎」「小指外転筋」「アドリアマイシン」 |
| 拡張検索 | 「ADME」「ADMA」「CADM」 |
| 関連記事 | 「A」「AD」 |
「ドキソルビシン」
- 英
- doxorubicin
- 同
- アドリアマイシン adriamycin ADM
- 化
- 塩酸ドキソルビシン 塩酸ドキソルビシン doxorubicin hydrochloride、ドキソルビシン塩酸塩
- 商
- Adriamycin, Rubex、アドリアシン
- 関
- アントラサイクリン
- 抗腫瘍性抗生物質製剤
- first aid step1 2006 p.207,233,307,309
特徴
- アントラサイクリン系抗腫瘍抗生物質
構造
作用機序
- 腫瘍細胞のDNAの二本鎖間にインターカレーションにより複合体を形成する。これによりDNAポリメラーゼ、RNAポリメラーゼの反応を阻害し、DNAの複製、RNAの合成を阻害
- generate free radicals and noncovalently intercalate in DNA(first aid step1 2006 p.309)
- 1. These compounds can intercalate with DNA, directly affecting transcription and replication.(GOO.1358)
- 2. A more important action is the ability of these drugs to form a tripartite complex with topoisomerase II and DNA. Formation of the tripartite complex with anthracyclines and with etoposide inhibits the re-ligation of the broken DNA strands, leading to apoptosis.(GOO.1358)
- 3. Anthracyclines can form semiquinone radical intermediates, which in turn can react with oxygen to produce superoxide anion radicals. These can generate both hydrogen peroxide and hydroxyl radicals (·OH), which attack DNA and oxidize DNA bases.(GOO.1358)
適応
- part of the ABVD combination regimen for Hodgkin’s and for myelomas, sarcomas, and solid tumors (breast, ovary, lung) (first aid step1 2006 p.309)
副作用
- cardiotoxicity; also myelosuppression and marked alopecia. Toxic extravasation(first aid step1 2006 p.309)
「無筋炎型皮膚筋炎」
- 英
- amyopathic dermatomyositis
- 同
- ADM、dermatomyositis sine myositis。無筋症型皮膚筋炎、非ミオパチー性皮膚筋炎
「小指外転筋」
起始
停止
- 小指(基節骨底の内側)
神経
機能
「アドリアマイシン」
「ADME」
| 吸収 | Absorption |
| 分布 | Distribution |
| 代謝 | Metabolism |
| 排泄 | Excretion |
薬物の投与経路と血中濃度
| 血中濃度
ピークまでの時間 |
血中濃度
ピークの高さ | |||
| 静脈注射 | i.v. | intravenous | ++++ | ++++ |
| 筋内注射 | i.m. | intramuscular | +++ | +++ |
| 皮下投与 | s.c. | subcutaneous | ++ | ++ |
| 経口投与 | p.o. | peroral | + | + |
「ADMA」
「CADM」
[★] clinically amyopathic dermatomyositis
- 関
- CADM-140, anti CADM-140 antibody
「A」
「AD」