C型ニーマン・ピック病、C型Niemann-Pick病
WordNet
- select carefully from a group; "She finally picked her successor"; "He picked his way carefully"
- remove in small bits; "pick meat from a bone"
- a heavy iron tool with a wooden handle and a curved head that is pointed on both ends; "they used picks and sledges to break the rocks" (同)pickax, pickaxe
- a small thin device (of metal or plastic or ivory) used to pluck a stringed instrument (同)plectrum, plectron
- a basketball maneuver; obstructing an opponent with ones body; "he was called for setting an illegal pick"
- a thin sharp implement used for removing unwanted material; "he used a pick to clean the dirt out of the cracks"
- attack with or as if with a pickaxe of ice or rocky ground, for example; "Pick open the ice" (同)break_up
- look for and gather; "pick mushrooms"; "pick flowers" (同)pluck, cull
- pilfer or rob; "pick pockets"
- provoke; "pick a fight or a quarrel"
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- an impairment of health or a condition of abnormal functioning
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
PrepTutorEJDIC
- (入念に)…‘を'『選ぶ』,選び取る / 〈草花・果実など〉‘を'『摘む』,もぐ / 〈鳥など〉‘の'羽をむしる;(…から)…‘を'むしる《+『名』+『from』+『名』》 / (とがった物で)…‘を'つつく,つついて穴をあける《+『名』+『with』+『名』》 / 〈鳥などが〉〈えさ〉‘を'つつく,つついて食べる / 〈争いなど〉‘を'しかける;(人に)〈口論など〉‘を'ふっかける《+『名』+『with』+『名』〈人〉》 / (針金などで)〈錠〉‘を'こじあける / 〈ポケット・さいふなど〉‘の'中身をすり取る / 〈弦楽器・弦〉‘を'指で鳴らす,つまびく / 入念に選ぶ / 〈鳥が〉えさをつつく;(食浴がなくて)〈人が〉(…を)少しずつ食べる《+『at』+『名』》 / 〈U〉(…の)選択(choice),(…を)選ぶこと(権利)《+『of』+『名』》 / 〈C〉(…から)選択された人(物);《the~》(…から)選ばれた最上の人(物)《+『of』+『名』》
- 《複合語を作って》「ほじる(つつく)道具」の意を表す / 《話》=plectrum
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
- 女性の話術芸人 =diseur
- carbonの化学記号
- 病気にかかった / 病的な,不健全な(morbid)
UpToDate Contents
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English Journal
- Initiation and discontinuation of substrate inhibitor treatment in patients with Niemann-Pick type C disease.
- Pérez-Poyato MS, Gordo MM, Marfa MP.SourceDepartment of Pediatric Neurology, Hospital de Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.
- Gene.Gene.2012 Sep 10;506(1):207-10. doi: 10.1016/j.gene.2012.06.054. Epub 2012 Jun 28.
- Niemann-Pick type C disease (NP-C) is a lysosomal storage disorder characterized by a progressive neurological deterioration. Different clinical forms have been defined based on patient age at neurological symptoms onset: perinatal, early infantile (EI), late infantile (LI), juvenile and adult. Ther
- PMID 22750297
- Arachidonic acid metabolism via cytosolic phospholipase A2 α induces cytotoxicity in niemann-pick disease type C cells.
- Nakamura H, Yasufuku K, Makiyama T, Matsumoto I, Fujino H, Murayama T.SourceLaboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chuo-ku, Chiba, Japan. nakahiro@faculty.chiba-u.jp
- Journal of cellular physiology.J Cell Physiol.2012 Jul;227(7):2847-55. doi: 10.1002/jcp.23025.
- Niemann-Pick disease type C (NPC) is a neurodegenerative lipid storage disorder caused by mutations in NPC1 or NPC2 genes. Loss of function of either protein results in the endosomal accumulation of cholesterol and other lipids. Here, we report that NPC1-deficient Chinese hamster ovary cells exhibit
- PMID 21928312
Japanese Journal
- BUTYRATE REDUCES FREE CHOLESTEROL ACCUMULATION IN NIEMANN-PICK DISEASE TYPE C1 CELLS (NOVA SCOTIA FORM) THROUGH THE INDUCTION OF ACID SPHINGOMYELINASE
- Oyama Chikako,Hirayama Masashi,Noguchi Atsuko,Arai Hirokazu,Takahashi Tsutomu
- 秋田医学 38(3-4), 111-119, 2012-03
- … Niemann-Pick disease type C (NPC) is an inherited disorder caused by mutations in either the NPC1 or the NPC2 gene that affect intracellular free cholesterol trafficking. … Acid sphingomyelinase (ASM) is a lysosomal enzyme in which an inherited deficiency leads to Niemann-Pick disease types A and B (NPDA/NPDB). …
- NAID 110009004246
- SECONDARY IMPAIRMENT OF INTRACELLULAR CHOLESTEROL TRANSPORT IN CELLS WITH NIEMANN-PICK DISEASE TYPE C
- Oyama Katsuyuki,Oyama Chikako,Takahashi Tsutomu
- 秋田医学 37(3-4), 153-162, 2011-03
- … Niemann-Pick disease type C (NPC) is an autosomal recessive lipidosis resulting from mutations of the NPC1 or NPC2 gene, clinically characterized by hepatosplenomegaly and progressive neurological symptoms including vertical supranuclear ophthalmoplegia, progressive ataxia, dystonia, and dementia. … Neurodegeneration in NPC shows a number of pathological features similar to those observed in Alzheimer disease. …
- NAID 110008728576
Related Links
- Niemann–Pick type C is a lysosomal storage disease associated with mutations in NPC1 and NPC2 genes. Niemann–Pick type C strikes an estimated 1:150,000 people. Approximately 50% of cases present before 10 years of age, but ...
- Niemann–Pick disease, type C: subacute/juvenile, includes types C1 (95% of type C) and C2. Type C is the most common form of the ... The incidence of Niemann–Pick disease type C is estimated to be 1 in 150,000. This corresponds to a total ...
Related Pictures
★リンクテーブル★
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- 英
- type C Niemann-Pick disease
- 関
- C型ニーマン・ピック病
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- 英
- type C Niemann-Pick disease
- 関
- C型Niemann-Pick病
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- 疾患:illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
- 特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
- something that is very wrong with people's attitudes, way of life or with society.
- 関
- ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness
- disease ≠ illness ≠ disorder
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- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
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オルトリン酸
- 関
- orthophosphate、orthophosphoric acid
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- 関
- form、mode、pattern、type