WordNet
- the amount that can be contained; "the gas tank has a capacity of 12 gallons" (同)content
- (computer science) the amount of information (in bytes) that can be stored on a disk drive; "the capacity of a hard disk drive is usually expressed in megabytes"
- a specified function; "he was employed in the capacity of director"; "he should be retained in his present capacity at a higher salary"
- the maximum production possible; "the plant is working at 80 per cent capacity"
- tolerance for alcohol; "he had drunk beyond his capacity"
- the power to learn or retain knowledge; in law, the ability to understand the facts and significance of your behavior (同)mental ability
- capability to perform or produce; "among his gifts is his capacity for true altruism"; "limited runway capacity"; "a great capacity for growth"
- press and smooth with a heated iron; "press your shirts"; "she stood there ironing" (同)iron_out, press
- a heavy ductile magnetic metallic element; is silver-white in pure form but readily rusts; used in construction and tools and armament; plays a role in the transport of oxygen by the blood (同)Fe, atomic number 26
- implement used to brand live stock (同)branding iron
- home appliance consisting of a flat metal base that is heated and used to smooth cloth (同)smoothing iron
- a golf club that has a relatively narrow metal head
- executed with proper legal authority; "a binding contract"
- the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
- strip sewn over or along an edge for reinforcement or decoration
- the capacity to attract and hold something
- determine the sum of; "Add all the people in this town to those of the neighboring town" (同)tot, tot up, sum, sum_up, summate, tote up, add, add together, tally, add up
- damage beyond the point of repair; "My son totaled our new car"; "the rock star totals his guitar at every concert"
- add up in number or quantity; "The bills amounted to $2,000"; "The bill came to $2,000" (同)number, add up, come, amount
- garments (clothes or linens) that are to be (or have been) ironed; "there was a basketful of ironing to do"
- the work of using heat to smooth washed clothes in order to remove any wrinkles
PrepTutorEJDIC
- 〈U〉《しばしばa capacity》(建物などの)『収容力』,(容器などの)『容量』,『容積』 / 〈U〉《しばしばa capacity》(人の)『能力』,才能;(物の)性能 / 〈C〉(…の)『資格』,地位《+『of』(『as』)+『名』》
- 〈U〉『鉄』 / 〈U〉鉄のように堅い(強い,冷たい)こと / 〈C〉鉄製の器具 / 〈C〉[電気]『アイロン』 / 〈C〉アイアン(球を打つ部分が金属のゴルフクラブ) / 〈C〉《複数形で》手かせ,足かせ / 《名詞の前にのみ用いて》『鉄の』,鉄製の / 鉄のように堅い(強い,冷たい) / …‘に'アイロンをかける / 〈人が〉アイロンをかける
- 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
- 『総計の』,全体の / 『全くの』,完全な(absolute) / 『合計』,総額,総数,総量(sum) / …‘を'合計する / 合計…‘に'なる,総額が…‘に'のぼる(amount to)
- アイロンかけ / アイロンかけをした(をする)衣類
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/21 22:41:03」(JST)
[Wiki en表示]
Total iron-binding capacity |
Diagnostics |
The transferrin molecule binds free iron and transports it in the blood.
|
MedlinePlus |
003489 |
LOINC |
14800-7, 35215-3, 2501-5 |
[edit on Wikidata]
|
Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures the blood's capacity to bind iron with transferrin.[1] It is performed by drawing blood and measuring the maximum amount of iron that it can carry, which indirectly measures transferrin[2] since transferrin is the most dynamic carrier. TIBC is less expensive than a direct measurement of transferrin.[3][4]
The TIBC should not be confused with the UIBC, or "unsaturated iron binding capacity" (22753-8 and 35216-1). The UIBC is calculated by subtracting the serum iron from the TIBC.[5]
Contents
- 1 Interpretation
- 2 Usual values
- 3 References
- 4 External Links
Interpretation
Taken together with serum iron and percent transferrin saturation clinicians usually perform this test when they are concerned about anemia, iron deficiency or iron deficiency anemia. However, because the liver produces transferrin, alterations in function (such as cirrhosis, hepatitis, or liver failure) must be considered when performing this test. It can also be an indirect test of liver function, but is rarely used for this purpose.
The percent transferrin saturation (i.e., the result of the formula of serum iron/TIBC x 100) can also be a useful indicator.
Condition |
Serum iron (highly variable) |
Transferrin and TIBC |
Percent transferrin saturation |
iron deficiency anemia |
Low |
High. The liver produces more transferrin, presumably attempting to maximize use of the little iron that is available. |
Low, as there is insufficient iron. |
anemia of chronic disease |
Low, as the body holds iron intracellularly with ferritin. |
Low. The body produces less transferrin (but more ferritin), presumably to keep iron away from pathogens that require it for their metabolism. This is mainly regulated by increased hepcidin production. |
Normal |
pregnancy or use of hormonal contraception, but without iron deficiency |
Normal |
High. The liver increases the production of transferrin, thus raising TIBC. |
Low, as there is excess transferrin with normal serum iron levels. |
These examples demonstrate that to properly understand a value for TIBC, one also must know the serum iron, the percent transferrin saturation, and the individual clinical situation. In modern laboratory testings, serum ferritin levels are generally accepted as reliable single indicators of the presence of iron deficiency.
Usual values
Reference ranges for blood tests, comparing blood content of iron and related compounds (shown in brown and orange) with other constituents.
Laboratories often use different units of measurement and "normal" may vary by population and the laboratory techniques used. Look at the individual laboratory reference values to interpret a specific test (for instance, your own). Example reference ranges are:
- Serum iron: Male 65–177 μg/dL (11.6–31.7 μmol/L); Female 50–170 μg/dL (9.0–30.4 μmol/L)
- TIBC: 250–370 μg/dL (45-66 μmol/L)[6]
- Transferrin saturation: Male 20–50%; Female 15–50%
- Serum ferritin: Male 20-250 μg/L, Female 15-150 μg/L[6]
μg/dL = micrograms per deciliter; μmol/L = micromoles per litre.
References
- ^ "MedlinePlus Medical Encyclopedia: Total iron binding capacity". Retrieved 2008-12-31.
- ^ Yamanishi H, Iyama S, Yamaguchi Y, Kanakura Y, Iwatani Y (January 2003). "Total iron-binding capacity calculated from serum transferrin concentration or serum iron concentration and unsaturated iron-binding capacity". Clin. Chem. 49 (1): 175–8. doi:10.1373/49.1.175. PMID 12507977.
- ^ Kasvosve I, Delanghe J (October 2002). "Total iron binding capacity and transferrin concentration in the assessment of iron status". Clin. Chem. Lab. Med. 40 (10): 1014–8. doi:10.1515/CCLM.2002.176. PMID 12476940.
- ^ Gambino R, Desvarieux E, Orth M, et al. (December 1997). "The relation between chemically measured total iron-binding capacity concentrations and immunologically measured transferrin concentrations in human serum". Clin. Chem. 43 (12): 2408–12. PMID 9439462.
- ^ "Iron Transport". Retrieved 2008-12-31.
- ^ a b Harrison's Principles of Internal Medicine. 17th Edition (2008). Pg. 2432 (Table 351-2)
External Links
- TIBC, UIBC and Transferrin Saturation at Lab Tests Online
References ranges for blood tests (CPT 82000–84999)
|
|
Electrolytes |
- Sodium
- Potassium
- Chloride
- Calcium
- Renal function
- Creatinine
- Urea
- BUN-to-creatinine ratio
- Plasma osmolality
- Serum osmolal gap
|
|
Acid-base |
- Anion gap
- Arterial blood gas
- Base excess
- Bicarbonate
- CO2 content
|
|
Iron tests |
- Ferritin
- Serum iron
- Transferrin saturation
- Total iron-binding capacity
- Transferrin
- Transferrin receptor
|
|
Hormones |
- ACTH stimulation test
- Thyroid function tests
- Thyroid-stimulating hormone
|
|
Metabolism |
|
|
Cardiovascular |
- Cardiac marker
- CPK-MB test
- Lactate dehydrogenase
- Myoglobin
- Glycogen phosphorylase isoenzyme BB
|
|
Liver function tests |
- Proteins
- Human serum albumin
- Serum total protein
- ALP
- transaminases
- Bilirubin
|
|
Pancreas |
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Body iron status and gastric cancer risk in the EURGAST study.
- Fonseca-Nunes A1, Agudo A1, Aranda N2, Arija V2, Cross AJ3, Molina E4,5, Sanchez MJ4,5, Bueno-de-Mesquita HB6,7,8,9, Siersema P6,7,8,9, Weiderpass E10,11,12,13, Krogh V14, Mattiello A15, Tumino R16, Saieva C17, Naccarati A18, Ohlsson B19, Sjöberg K19, Boutron-Ruault MC20,21,22, Cadeau C20,21,22, Fagherazzi G20,21,22, Boeing H23, Steffen A23, Kühn T24, Katzke V24, Tjønneland A25, Olsen A25, Khaw KT26, Wareham N26, Key T27, Lu Y3, Riboli E3, Peeters PH28, Gavrila D5,29,30, Dorronsoro M31, Quirós JR32, Barricarte A33,34,35, Jenab M34, Zamora-Ros R34, Freisling H34, Trichopoulou A35,36, Lagiou P35,36, Bamia C35,36, Jakszyn P1.
- International journal of cancer. Journal international du cancer.Int J Cancer.2015 Dec 15;137(12):2904-14. doi: 10.1002/ijc.29669. Epub 2015 Jul 16.
- Although it appears biologically plausible for iron to be associated with gastric carcinogenesis, the evidence is insufficient to lead to any conclusions. To further investigate the relationship between body iron status and gastric cancer risk, we conducted a nested case-control study in the multice
- PMID 26135329
- Elevated Total Iron-Binding Capacity Is Associated with an Increased Risk of Celiac Disease.
- Letner D1, Peloquin J2,3, Durand J4, Rutherford A5,6, Yajnik V7,8, Khalili H9,10, Garber J11,12.
- Digestive diseases and sciences.Dig Dis Sci.2015 Dec;60(12):3735-42. doi: 10.1007/s10620-015-3791-9. Epub 2015 Jul 15.
- BACKGROUND: Several lines of evidence suggest that abnormal iron homeostasis may itself play an important role in the development of celiac disease.AIM: We sought to determine whether abnormalities in iron status could be detected prior to the diagnosis of celiac disease, and to understand the relat
- PMID 26173503
Japanese Journal
- Comparison of Pain and Efficacy of Darbepoetin Alfa and Epoetin Beta Pegol Treatment in Patients Receiving Peritoneal Dialysis
- , , , , , , , ,
- Journal of Nippon Medical School 82(1), 21-26, 2015
- … We also measured variables related to anemia and iron metabolism. … There were no significant differences in iron metabolism, as shown by serum iron levels and total iron-binding capacity, in either group. …
- NAID 130004926740
- 小島 菜実絵,水野 秀一,宮原 恵子,小田 和人,松尾 嘉代子,飯出 一秀,吉村 良孝,田井 健太郎,今村 裕行
- 総合健診 41(2), 274-282, 2014
- 大学女子バレーボール、テニス、空手道部員42名を対象に貧血の栄養サポートにおける基礎的情報を得ることを目的とし、栄養素等・食品群別摂取状況、血液生化学検査値について検討した。対象者は血清フェリチン値を基に3群(Low、Middle、High群)に分類した。栄養素等摂取量では銅を除いた項目の適正量を3群とも満たしておらず、さらにLow群はクリプトキサンチンおよびビタミンCが有意な低値を示した。血液 …
- NAID 130004936221
Related Links
- Total iron binding capacity (TIBC) is a blood test to see if you have too much or too little iron in your blood. Iron moves through the blood attached to a ... When the needle is inserted to draw blood, some people feel moderate pain.
- Explaines how the TIBC, UIBC, and transferrin tests are used, when TIBC, UIBC, and transferrin tests are ordered, and what the results of these tests might mean. Total iron-binding capacity (TIBC) is most frequently used along with a ...
★リンクテーブル★
[★]
- 関
- affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union
[★]
- (呼吸器)volumeの和・差はcapacityと呼ぶ傾向があるみたい
- 関
- ability、capability、capacitance、competence、competent、facility、power
[★]
- 関
- all、altogether、common、entire、entirety、gross、overall、total amount、whole
[★]
鉄