サルブタモール。硫酸サルブタモール
WordNet
- convert into a sulfate
- a salt or ester of sulphuric acid (同)sulphate
UpToDate Contents
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English Journal
- Evaluation of air-interfaced Calu-3 cell layers for investigation of inhaled drug interactions with organic cation transporters in vitro.
- Mukherjee M, Pritchard DI, Bosquillon C.SourceDivision of Drug Delivery and Tissue Engineering, School of Pharmacy, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom.
- International journal of pharmaceutics.Int J Pharm.2012 Apr 15;426(1-2):7-14. Epub 2012 Jan 13.
- A physiologically pertinent in vitro model is urgently needed for probing interactions between inhaled drugs and the organic cation transporters (OCT) in the bronchial epithelium. This study evaluated OCT expression, functionality, inhibition by common inhaled drugs and impact on formoterol transepi
- PMID 22265910
- Chronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.
- Lin R, Degan S, Theriot BS, Fischer BM, Strachan RT, Liang J, Pierce RA, Sunday ME, Noble PW, Kraft M, Brody AR, Walker JK.SourceDivision of Pulmonary, Allergy and Critical Care Medicine, Duke University Medical Center, Durham, NC, USA Center for Molecular and Biomolecular Imaging, Duke University, Durham, NC, USA Division of Pediatric Pulmonary and Sleep Medicine, Duke University Medical Center, Durham, NC, USA Department of Medicine, Duke University Medical Center, Durham, NC, USA Department of Pulmonary Medicine, Washington University, St. Louis, MO, USA Department of Pathology, Duke University Medical Center, Durham, NC, USA Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC, USA.
- British journal of pharmacology.Br J Pharmacol.2012 Apr;165(7):2365-2377. doi: 10.1111/j.1476-5381.2011.01725.x.
- BACKGROUND AND PURPOSE Inhalation of a β-adrenoceptor agonist (β-agonist) is first-line asthma therapy, used for both prophylaxis against, and acute relief of, bronchoconstriction. However, repeated clinical use of β-agonists leads to impaired bronchoprotection and, in some cases, adverse patient
- PMID 22013997
Japanese Journal
- 病棟管理吸入液の衛生管理に関する多施設での実態調査
- 日本環境感染学会誌 = Japanese journal of environmental infecions 32(5), 258-262, 2017
- NAID 40021340937
- 病棟管理吸入液の衛生管理に関する多施設での実態調査
- Study of pH Stability of <i>R</i>-Salbutamol Sulfate Aerosol Solution and Its Antiasthmatic Effects in Guinea Pigs
Related Links
- albuterol sulfate (salbutamol sulfate) AccuNeb, Gen-Salbutamol (CA), Nu-Salbutamol (CA), ProAir HFA, Proventil HFA, Ventolin HFA, Vospire-ER Pharmacologic class: Sympathomimetic (beta 2-adrenergic agonist) Therapeutic class: Bronchodilator, antiasthmatic
- Salbutamol (Albuterol) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM. Find all the information about Salbutamol sulfate (Albuterol) for cell signaling research. ... MG-132 MG ...
Related Pictures
★リンクテーブル★
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- 英
- salbutamol
- ラ
- salbutamolum
- 化
- 硫酸サルブタモール salbutamol sulfate
- 商
- アイロミール、アスタージス、サルタノール、ベネトリン Ventolin、レナピリン
- 関
- アセチルコリン受容体
特徴
構造
作用機序
- 気管支平滑筋、肝臓のβ2受容体に結合
- (わずかではあるが)心臓のβ1受容体に結合
薬理作用
適応
副作用
- β1受容体も刺激するので心拍数↑
- 日本での報告例はない
- 強心配糖体や利尿薬を服用の患者で問題となる
- 肝臓に発現しているβ2受容体に作用→グリコーゲン分解→血糖値↑
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- 関
- H2SO4、inorganic sulfate、sulfate ester、sulfated、sulfation、sulfuric acid、sulfuric acid ester、sulphate、sulphuric acid
[★]
- 関
- sulfate、sulfation、sulphate
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スルファ、サルファ