WordNet

impervious to being affected; "resistant to the effects of heat"; "resistant to persuasion"
any of various antibiotics obtained from Penicillium molds (or produced synthetically) and used in the treatment of various infections and diseases
respiratory disease characterized by inflammation of the lung parenchyma (excluding the bronchi) with congestion caused by viruses or bacteria or irritants
spherical Gram-positive bacteria occurring in pairs or chains; cause e.g. scarlet fever and tonsillitis (同)streptococci, strep

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1. β-ラクタム系抗菌薬に対する肺炎レンサ球菌の耐性 resistance of streptococcus pneumoniae to beta lactam antibiotics
2. 難治性肺炎 nonresolving pneumonia
3. 侵襲性肺炎球菌（Streptococcus pneumoniae）感染症および菌血症 invasive pneumococcal streptococcus pneumoniae infections and bacteremia
4. 無脾症患者における敗血症の臨床的特徴およびマネージメント clinical features and management of sepsis in the asplenic patient
5. 成人における細菌性髄膜炎の初期治療および予後 initial therapy and prognosis of bacterial meningitis in adults

Genetic Analyses of Penicillin Binding Protein Determinants in Multidrug-Resistant Streptococcus pneumoniae Serogroup 19 CC320/271 Clone with High-Level Resistance to Third-Generation Cephalosporins.

Ip M1, Ang I2, Liyanapathirana V2, Ma H2, Lai R2.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Jul;59(7):4040-5. doi: 10.1128/AAC.00094-15. Epub 2015 Apr 27.
We describe the dissemination of a multidrug-resistant (MDR) serogroup 19 pneumococcal clone of representative multilocus sequence type 271 (ST271) with high-level resistance to cefotaxime in Hong Kong and penicillin binding protein (pbp) genes and its relationships to Taiwan(19F)-14 and the prevale
PMID 25918136

Straume D1, Stamsås GA1, Håvarstein LS2.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.Infect Genet Evol.2015 Jul;33:371-380. doi: 10.1016/j.meegid.2014.10.020. Epub 2014 Nov 4.
Streptococcus pneumoniae is a frequent colonizer of the human nasopharynx that has the potential to cause severe infections such as pneumonia, bacteremia and meningitis. Despite considerable efforts to reduce the burden of pneumococcal disease, it continues to be a major public health problem. After
PMID 25445643

Effect of dexamethasone on the efficacy of daptomycin in the therapy of experimental pneumococcal meningitis.

Vivas M1, Force E2, Tubau F3, El Haj C2, Ariza J2, Cabellos C2.
International journal of antimicrobial agents.Int J Antimicrob Agents.2015 Jul;46(1):28-32. doi: 10.1016/j.ijantimicag.2015.01.014. Epub 2015 Mar 6.
This study aimed to determine the effect of dexamethasone in combination with low-dose or high-dose daptomycin for the treatment of penicillin- and cephalosporin-resistant pneumococcal meningitis. Efficacy (ΔCFU/mL) and cerebrospinal fluid (CSF) levels of daptomycin at 15mg/kg and 25mg/kg were stud
PMID 25813395

星野直,有本友季子,仲野敦子
小児耳鼻咽喉科 35(1), 12-16, 2014
2 歳 3 か月の男児。結合型 7 価肺炎球菌ワクチン（PCV7）4 回接種済み。いびき，無呼吸に対し，全身麻酔下にアデノイド切除，口蓋扁桃摘出術を施行した。周術期抗菌薬は ampicillin を静注で使用（当日は術直前および10時間後に静注）。POD1 に40℃の発熱を，POD2 に痙攣を認めた。血液，髄液より肺炎球菌が分離され，同菌による細菌性髄膜炎と診断。急性期に集中治療を要したが，後 …
NAID 130004992684

Clinical Characteristics of Acute Otitis Media in Children under the Age of 2 Years and the Efficacy of Tosufloxacin

, , , , ,
耳鼻咽喉科臨床　補冊 138(0), 16-17, 2014
… In the AOM<2 group, Haemophilus influenzae and Streptococcus pneumoniae, the 2 major pathogenic bacteria, were responsible for 66.7% and 25.6% of the cases, respectively, while in the AOM≧2 group, Haemophilus influenzae and Streptococcus pneumoniae were responsible for 41.1% and 70.5% of the cases, respectively. …
NAID 130004834018

宮部はるか,川島佳代子
耳鼻咽喉科臨床 107(8), 609-615, 2014
… Since Streptococcus pneumonia has severe pathogenicity and the incidence of penicillin-resistant S. … pneumoniae has been increasing, it is important to identify S. … pneumoniae is one of the normal inhabitants of the nasopharynxes, so it is difficult to identify it as a pathogenic bacterium. … pneumoniae HS (HS kit) for the detection of pathogenic bacteria associated with acute rhinosinusitis. …
NAID 130004679704