WordNet

combine (electronic signals); "mixing sounds"
add as an additional element or part; "mix water into the drink" (同)mix in
the act of mixing together; "paste made by a mix of flour and water"; "the mixing of sound channels in the recording studio" (同)commixture, admixture, mixture, intermixture, mixing
an event that combines things in a mixture; "a gradual mixture of cultures" (同)mixture
a commercially prepared mixture of dry ingredients (同)premix
to bring or combine together or with something else; "resourcefully he mingled music and dance" (同)mingle, commix, unify, amalgamate
infertility between hybrids
a gland in which gametes (sex cells) are produced (同)sex gland
of or relating to the gonads; "gonadal hormones"

PrepTutorEJDIC

〈複数のもの〉‘を'『混ぜ合わせる』,混合する,混同する / …‘を'混ぜ合わせて作る,調合して作る / …‘を'寄せ集める,まとめる / 〈物が〉(…と)混ざる,混合する《+『with』+『名』》 / 〈人が〉(他の人と)交わる,交際する《+『with』+『名』》 / 〈C〉〈U〉混合 / 〈C〉混合物(食品,薬) / 〈C〉〈U〉(水・火を加えて即席にでき上がる)素(もと),ミックス
性腺(せん),生殖腺
(異なった成分(要素)のものが)混ざった,混合の,混成の / 男女混合の / 人種(宗教・国籍など)が違う人々の(から成る)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/01/12 13:20:30」(JST)

wiki en

Mixed gonadal dysgenesis is a condition of unusual and asymmetrical gonadal development leading to an unassigned sex differentiation. A number of differences have been reported in the karyotype, most commonly a mosaicism 45,X/ 46, XY. If Turner syndrome is defined as a condition where one sex chromosome is absent or abnormal, mixed gonadal dysgenesis may be interpreted as a specific variation of Turner’s. The phenotypical expression may be ambiguous, intersex, or male, or female pending the extent of the mosaicism.

It has been pointed out that the gonads may not be symmetrical, thus the development of the Müllerian duct and Wolffian duct may be asymmetrical, too.^[1] Because of the presence of dysgenetic gonadal tissue and Y chromosome material, there is a high risk of the development of a gonadoblastoma, thus removal of the gonads is usually indicated.

Although similar in some ways to true hermaphroditism, the conditions can be distinguished histologically.^[2]

References

^ Donahoe PK, Crawford JD, Hendren WH (1979). "Mixed gonadal dysgenesis, pathogenesis, and management". J. Pediatr. Surg. 14 (3): 287–300. doi:10.1016/S0022-3468(79)80486-8. PMID 480090. http://linkinghub.elsevier.com/retrieve/pii/S0022346879000531.
^ Kim KR, Kwon Y, Joung JY, Kim KS, Ayala AG, Ro JY (October 2002). "True hermaphroditism and mixed gonadal dysgenesis in young children: a clinicopathologic study of 10 cases". Mod. Pathol. 15 (10): 1013–9. doi:10.1097/01.MP.0000027623.23885.0D. PMID 12379746.

External links

Wikimedia Commons has media related to: Mixed gonadal dysgenesis

Mixed gonadal dysgenesis Children's Hospital Boston

UpToDate Contents

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1. 外陰部異常を有する幼児の評価 evaluation of the infant with ambiguous genitalia
2. 性染色体異常 sex chromosome abnormalities
3. 外陰部異常を有する幼児のマネージメント management of the infant with ambiguous genitalia
4. アンドロゲン受容体障害の診断および治療 diagnosis and treatment of disorders of the androgen receptor
5. 精細管内胚細胞腫瘍、未分類（精巣上皮内癌、精巣上皮内腫瘍） testicular intratubular germ cell neoplasia unclassified testicular carcinoma in situ testicular intraepithelial neoplasia

English Journal

OVOTESTICULAR DISORDER OF SEX DEVELOPMENT: A SINGLE-CENTER EXPERIENCE.

Khadilkar KS, Budyal SR, Kasaliwal R, Sathe PA, Kandalkar B, Sanghvi BV, Parelkar SV, Lila AR, Bandgar T, Shah NS.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists.Endocr Pract.2015 Jul;21(7):770-6. doi: 10.4158/EP15606.OR. Epub 2015 Mar 18.
OBJECTIVE: Ovotesticular disorder of sex development (OT DSD) is a rare disorder of sex development characterized by the presence in the same individual of both histologically proven testis and ovary. There are scant data from the Indian subcontinent regarding this disorder. The aim of this study wa
PMID 25786559

Gonadal malignancy risk and prophylactic gonadectomy in disorders of sexual development.

Abacı A, Çatlı G, Berberoğlu M.
Journal of pediatric endocrinology & metabolism : JPEM.J Pediatr Endocrinol Metab.2015 Apr 16. pii: /j/jpem.ahead-of-print/jpem-2014-0522/jpem-2014-0522.xml. doi: 10.1515/jpem-2014-0522. [Epub ahead of print]
Disorders of sex development (DSD) are a generic definition including any problem noted at birth where the genitalia are atypical in relation to the chromosomes or gonads. The most important clinical problems in DSD comprise physical and psychological disturbances and the risk of gonadal tumor devel
PMID 25879315

Identification of X monosomy cells from a gonad of mixed gonadal dysgenesis with a 46,XY karyotype: case report.

Nishina-Uchida N1, Fukuzawa R, Hasegawa Y, Morison IM.
Medicine.Medicine (Baltimore).2015 Apr;94(14):e720. doi: 10.1097/MD.0000000000000720.
Mixed gonadal dysgenesis (MGD) is a disorder of sexual development that typically has a mosaic 45,X/46,XY karyotype. A 1-year-old infant with 46,XY identified by peripheral blood karyotype demonstrated clinical manifestations and gonadal pathologic features of MGD. Fluorescence in situ hybridization
PMID 25860218

Japanese Journal

性分化疾患治療における腹腔鏡の有用性

Japanese Journal of Endourology 27(1), 169-173, 2014
NAID 130004627238

46, XY性腺形成異常症 (Swyer 症候群) に発生した卵巣混合型悪性胚細胞腫瘍の1例

日本臨床細胞学会雑誌 51(1), 22-27, 2012-01-22
NAID 10030025756

46,XY 性腺形成異常症 (Swyer 症候群) に発生した卵巣混合型悪性胚細胞腫瘍の 1 例

日本臨床細胞学会雑誌 51(1), 22-27, 2012
NAID 130004696392

Related Pictures

★リンクテーブル★

リンク元	「混合型性腺形成不全症」「混合型性腺異形成症」「混合性性腺形成不全」
関連記事	「dysgenesis」「mix」「gonadal」「gonad」「mixed」

「混合型性腺形成不全症」

Mixed gonadal dysgenesis
	Classification and external resources
DiseasesDB	29266
MeSH	D006060

　　[★]

英: mixed gonadal dysgenesis
同: 混合型性腺形成異常症

[show details]

混合型性腺形成不全症 : 60 件
混合型性腺形成異常症 : 15 件

「混合型性腺異形成症」

　　[★]

英: mixed gonadal dysgenesis

「混合性性腺形成不全」

　　[★]

英: mixed gonadal dysgenesis

「dysgenesis」

　　[★]

異形成、形成不全、形成異常、形成不全症、形成異常症、発育異常、異発生

関: aplasia、aplastic、dysgenetic、dysgenic、dysplasia、dysplastic、heteroplasia、heteroplasmy、hypoplasia、malformation、metaplasia、metaplastic

「mix」

　　[★]

混合、混合する、混ぜる

関: admix、admixture、blend、intermingle、merge、mixture、scramble、shuffle、shuffling

「gonadal」

　　[★]

adj.

生殖腺の、性腺の

関: genital gland、gonad、gonad gland

「gonad」

　　[★]

n.

(解剖)生殖巣、生殖腺、性腺、性巣

関: gonadal

「mixed」

　　[★]

混合性の

関: combined

[1] Donahoe PK, Crawford JD, Hendren WH (1979). "Mixed gonadal dysgenesis, pathogenesis, and management". J. Pediatr. Surg. 14 (3): 287–300. doi:10.1016/S0022-3468(79)80486-8. PMID 480090. http://linkinghub.elsevier.com/retrieve/pii/S0022346879000531.

[pmid12379746-2] Kim KR, Kwon Y, Joung JY, Kim KS, Ayala AG, Ro JY (October 2002). "True hermaphroditism and mixed gonadal dysgenesis in young children: a clinicopathologic study of 10 cases". Mod. Pathol. 15 (10): 1013–9. doi:10.1097/01.MP.0000027623.23885.0D. PMID 12379746.

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案内

案内

mixed gonadal dysgenesis