eukaryotic translation initiation factor 4A

• 真核生物・訳開始因子4A

関

eIF-4A、eIF4A、eukaryotic initiation factor-4A

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. (genetics) the process whereby genetic information coded in messenger RNA directs the formation of a specific protein at a ribosome in the cytoplasm
8. (mathematics) a transformation in which the origin of the coordinate system is moved to another position but the direction of each axis remains the same
9. the act of uniform movement (同)displacement
10. a written communication in a second language having the same meaning as the written communication in a first language (同)interlingual rendition, rendering, version
11. a uniform movement without rotation
12. rewording something in less technical terminology
13. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
14. a concept whose truth can be proved; "scientific hypotheses are not facts"
15. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
16. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
17. the act of starting something for the first time; introducing something new; "she looked forward to her initiation as an adult"; "the foundation of a new scientific society" (同)founding, foundation, institution, origination, creation, innovation, introduction, instauration
18. a formal entry into an organization or position or office; "his initiation into the club"; "he was ordered to report for induction into the army"; "he gave a speech as part of his installation into the hall of fame" (同)induction, installation
19. having cells with `good or membrane-bound nuclei (同)eucaryotic

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈U〉『訳すこと,翻訳』 / 〈C〉翻訳されたもの
3. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
4. 〈U〉開始;創業 / 〈U〉入会,入門;〈C〉入会(入門)式 / 〈U〉手ほどき,伝授

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. 分子遺伝学の原理 principles of molecular genetics
• 2. 消失性白質疾患（Vanishing white matter disease） vanishing white matter disease
• 3. von Willebrand因子の生物学および正常機能 biology and normal function of von willebrand factor
• 4. 跛行の内科的マネージメント medical management of claudication
• 5. サラセミア症候群の分子病理 molecular pathology of the thalassemic syndromes

English Journal

• Human translation initiation factor eIF4G1 possesses a low-affinity ATP binding site facing the ATP-binding cleft of eIF4A in the eIF4G/eIF4A complex.

• Akabayov SR1, Akabayov B, Wagner G.
• Biochemistry.Biochemistry.2014 Oct 21;53(41):6422-5. doi: 10.1021/bi500600m. Epub 2014 Oct 8.
• Eukaryotic translation initiation factor 4G (eIF4G) plays a crucial role in translation initiation, serving as a scaffolding protein binding several other initiation factors, other proteins, and RNA. Binding of eIF4G to the ATP-dependent RNA helicase eukaryotic translation initiation factor 4A (eIF4
• PMID 25255371

• MicroRNAs trigger dissociation of eIF4AI and eIF4AII from target mRNAs in humans.

• Fukao A1, Mishima Y2, Takizawa N3, Oka S4, Imataka H5, Pelletier J6, Sonenberg N6, Thoma C7, Fujiwara T8.
• Molecular cell.Mol Cell.2014 Oct 2;56(1):79-89. doi: 10.1016/j.molcel.2014.09.005.
• In animals, key functions of microRNA-induced silencing complex (miRISC) are translational repression and deadenylation followed by mRNA decay. While miRISC represses translation initiation, it is poorly understood how miRISC exerts this function. Here we assessed the effect of miRISC on synergistic
• PMID 25280105

• MicroRNAs block assembly of eIF4F translation initiation complex in Drosophila.

• Fukaya T1, Iwakawa HO2, Tomari Y3.
• Molecular cell.Mol Cell.2014 Oct 2;56(1):67-78. doi: 10.1016/j.molcel.2014.09.004.
• miRNAs silence their complementary target mRNAs by translational repression as well as by poly(A) shortening and mRNA decay. In Drosophila, miRNAs are typically incorporated into Argonaute1 (Ago1) to form the effector complex called RNA-induced silencing complex (RISC). Ago1-RISC associates with a s
• PMID 25280104

Japanese Journal

• Hippuristanol Reduces the Viability of Primary Effusion Lymphoma Cells both in Vitro and in Vivo

• Ishikawa Chie,Tanaka Junichi,Katano Harutaka,Senba Masachika,Mori Naoki
• Marine Drugs 11(9), 3410-3424, 2013-09
• … Hippuristanol is extracted from Okinawan coral Isis hippuris, and inhibits translational initiation by blocking eukaryotic initiation factor 4A, an ATP-dependent RNA helicase, binding to mRNA. … Recently, there has been much interest in targeting translation initiation as an anticancer therapy. …
• NAID 120005347046

• Adenosine 5'-O-(3-thio)triphosphate (ATPγS) is a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A

• PECK M. L.
• RNA 9, 1180-1187, 2003
• NAID 30022824805

• Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A

• IMATAKA H.
• Mol Cell Biol 17, 6940-6947, 1997
• NAID 80009969881

Related Links

• Eukaryotic translation initiation factor 4 gamma - Wikipedia, the free ...

Eukaryotic translation initiation factor 4 gamma 1 is a protein that in humans is encoded by the EIF4G1 gene. ... "Human eukaryotic translation initiation factor 4G (eIF4G) possesses two separate and independent binding sites for eIF4A".

• Eukaryotic initiation factor - Wikipedia, the free encyclopedia

Eukaryotic initiation factors (eIF) are proteins involved in the initiation phase of eukaryotic translation. They function in forming ... Contents. 1 eIF4 (eIF4F); 2 eIF1 & eIF3; 3 eIF2; 4 eIF5 & eIF5B; 5 eIF6; 6 See also; 7 References; 8 External links  ...

---

★リンクテーブル★

リンク元	「真核生物翻訳開始因子4A」「eukaryotic initiation factor-4A」「eIF4A」
関連記事	「initiation」「fact」「factor」「eukaryotic」「translation」

「真核生物翻訳開始因子4A」

　　[★]

英

eukaryotic initiation factor-4A、eukaryotic translation initiation factor 4A、eIF4A、eIF-4A

関

・訳開始因子4A

「eukaryotic initiation factor-4A」

　　[★]

• 真核生物・訳開始因子4A、・訳開始因子4A

関

eIF-4A、eIF4A、eukaryotic translation initiation factor 4A

「eIF4A」

　　[★]

• 真核生物・訳開始因子4A

関

eIF-4A、eukaryotic initiation factor-4A、eukaryotic translation initiation factor 4A

「initiation」

　　[★]

• n.

• 開始、惹起、イニシエーション

関

commence、commencement、evoke、initiate、institute、mount、onset、start

　 　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「eukaryotic」

　　[★]

• 真核生物の

関

eucaryote、eukaryote、eukaryotic organism

　

「translation」

　　[★]

• n.

• 翻訳