eukaryotic initiation factor-4A

• 真核生物・訳開始因子4A、・訳開始因子4A

関

eIF-4A、eIF4A、eukaryotic translation initiation factor 4A

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
8. a concept whose truth can be proved; "scientific hypotheses are not facts"
9. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
10. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
11. the act of starting something for the first time; introducing something new; "she looked forward to her initiation as an adult"; "the foundation of a new scientific society" (同)founding, foundation, institution, origination, creation, innovation, introduction, instauration
12. a formal entry into an organization or position or office; "his initiation into the club"; "he was ordered to report for induction into the army"; "he gave a speech as part of his installation into the hall of fame" (同)induction, installation
13. having cells with `good or membrane-bound nuclei (同)eucaryotic

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
3. 〈U〉開始;創業 / 〈U〉入会,入門;〈C〉入会(入門)式 / 〈U〉手ほどき,伝授

UpToDate Contents

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• 1. 血友病患者における第VIIIおよび第IX因子阻害物質 factor viii and factor ix inhibitors in patients with hemophilia
• 2. 後天性の凝固因子阻害物質 acquired inhibitors of coagulation
• 3. Overview of hemostasis
• 4. Direct oral anticoagulants: Dosing and adverse effects
• 5. 第ⅩＩ因子欠乏症 factor xi deficiency

English Journal

• Simplified Silvestrol Analogues with Potent Cytotoxic Activity.

• Hawkins BC1, Lindqvist LM, Nhu D, Sharp PP, Segal D, Powell AK, Campbell M, Ryan E, Chambers JM, White JM, Rizzacasa MA, Lessene G, Huang DC, Burns CJ.
• ChemMedChem.ChemMedChem.2014 Mar 27. doi: 10.1002/cmdc.201400024. [Epub ahead of print]
• The complex natural products silvestrol (1) and episilvestrol (2) are inhibitors of translation initiation through binding to the DEAD-box helicase eukaryotic initiation factor 4A (eIF4A). Both compounds are potently cytotoxic to cancer cells in vitro, and 1 has demonstrated efficacy in vivo in se
• PMID 24677741

• Investigation of the conserved glutamate immediately following the DEAD box in eukaryotic translation initiation factor 4AI.

• Patel K1, Shah GK, Kommaraju SS, Low WK.
• Biochemistry and cell biology = Biochimie et biologie cellulaire.Biochem Cell Biol.2014 Feb;92(1):33-42. doi: 10.1139/bcb-2013-0076. Epub 2013 Dec 4.
• The DExD-box family (DEAD-box) of proteins was surveyed for eukaryotic translation initiation factor 4A-specific sequences surrounding the DEAD box. An eIF4A-unique glutamate residue (E186 in eIF4AI) was identified immediately following the D-E-A-D sequence in eIF4AI, II, and III that was found to b
• PMID 24471916

• The diverse roles of the eIF4A family: you are the company you keep.

• Lu WT, Wilczynska A, Smith E, Bushell M.
• Biochemical Society transactions.Biochem Soc Trans.2014 Feb;42(1):166-72. doi: 10.1042/BST20130161.
• The eIF4A (eukaryotic initiation factor 4A) proteins belong to the extensive DEAD-box RNA helicase family, the members of which are involved in many aspects of RNA metabolism by virtue of their RNA-binding capacity and ATPase activity. Three eIF4A proteins have been characterized in vertebrates: eIF
• PMID 24450646

Japanese Journal

• The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis

• PAUSE A
• Mol Cell Biol 13, 6789-6798, 1993
• NAID 80007290684

• The product of the Drosophila vasa is very similar to eukaryotic initiation factor-4A.

• LASKO P. F.
• Nature 335, 611-617, 1988
• NAID 80004286150

Related Links

• EIF4A1 - Eukaryotic initiation factor 4A-I - Homo sapiens ...

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in ...

• Eukaryotic Translation Initiation Factor 4AIII (eIF4AIII) Is ...

Eukaryotic initiation factor 4A (eIF4A) is an RNA-dependent ATPase and ATP-dependent RNA helicase that is thought to melt the 5′ proximal secondary structure of eukaryotic mRNAs to facilitate attachment of the 40S ...

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★リンクテーブル★

リンク元	「真核生物翻訳開始因子4A」「eIF4A」「eukaryotic translation initiation factor 4A」「翻訳開始因子4A」
関連記事	「initiation」「fact」「factor」「eukaryotic」

「真核生物翻訳開始因子4A」

　　[★]

英

eukaryotic initiation factor-4A、eukaryotic translation initiation factor 4A、eIF4A、eIF-4A

関

・訳開始因子4A

「eIF4A」

　　[★]

• 真核生物・訳開始因子4A

関

eIF-4A、eukaryotic initiation factor-4A、eukaryotic translation initiation factor 4A

「eukaryotic translation initiation factor 4A」

　　[★]

• 真核生物・訳開始因子4A

関

eIF-4A、eIF4A、eukaryotic initiation factor-4A

「翻訳開始因子4A」

　　[★]

英

eukaryotic initiation factor-4A

関

真核生物・訳開始因子4A

「initiation」

　　[★]

• n.

• 開始、惹起、イニシエーション

関

commence、commencement、evoke、initiate、institute、mount、onset、start

　 　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「eukaryotic」

　　[★]

• 真核生物の

関

eucaryote、eukaryote、eukaryotic organism