WordNet

the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer (同)oestradiol

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/12/08 09:53:25」(JST)

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References

^ Christoph Zink (1 January 1988). Dictionary of Obstetrics and Gynecology. Walter de Gruyter. p. 86. ISBN 978-3-11-085727-6. http://books.google.com/books?id=EQlvzV9V7xIC&pg=PA86. Retrieved 20 May 2012.
^ A. D. Roberts (1991). Dictionary of Steroids: Chemical Data, Structures, and Bibliographies. CRC Press. p. 415. ISBN 978-0-412-27060-4. http://books.google.com/books?id=qw5X0NK1A90C&pg=PA415. Retrieved 20 May 2012.
^ Index Nominum 2000: International Drug Directory. Taylor & Francis US. 2000. p. 405. ISBN 978-3-88763-075-1. http://books.google.com/books?id=5GpcTQD_L2oC&pg=PA405. Retrieved 20 May 2012.
^ Samuel S. C. Yen (1991). Reproductive endocrinology: physiology, pathophysiology, and clinical management. Saunders. ISBN 978-0-7216-3206-3. http://books.google.com/books?id=RN1qAAAAMAAJ. Retrieved 20 May 2012.
^ Düsterberg B, Nishino Y (December 1982). "Pharmacokinetic and pharmacological features of oestradiol valerate". Maturitas 4 (4): 315–24. PMID 7169965. http://linkinghub.elsevier.com/retrieve/pii/0378-5122(82)90064-0.
^ "Progynova 1mg (SPC) | Drugs.com" (HTML). http://www.drugs.com/uk/progynova-1mg-spc-3430.html. Retrieved 2012-09-06.
^ Sriram. Medicinal Chemistry. Pearson Education India. p. 427. ISBN 978-81-317-0031-0. http://books.google.com/books?id=9HSoZrcBRl0C&pg=PA427. Retrieved 20 May 2012.
^ Oriowo MA, Landgren BM, Stenström B, Diczfalusy E (April 1980). "A comparison of the pharmacokinetic properties of three estradiol esters". Contraception 21 (4): 415–24. PMID 7389356.

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1. 閉経期のホルモン療法で用いる製剤 preparations for menopausal hormone therapy
2. Uncommon congenital adrenal hyperplasias
3. エストロゲン・プロゲスチン避妊剤の使用に関する概要 overview of the use of estrogen progestin contraceptives
4. 思春期における多嚢胞性卵巣症候群の診断的評価 diagnostic evaluation of polycystic ovary syndrome in adolescents
5. 緊急避妊剤 emergency contraception

English Journal

Comparison of the symptomatic response in Indian menopausal women with different estrogen preparations for the treatment of menopausal symptoms: a randomized controlled trial.

Malik S1, Pannu D2, Prateek S1, Sinha R1, Gaikwad H1.
Archives of gynecology and obstetrics.Arch Gynecol Obstet.2016 Jun;293(6):1325-33. doi: 10.1007/s00404-016-4034-9. Epub 2016 Feb 16.
PURPOSE: To compare symptomatic response in Indian women using different estrogen preparations for treatment of menopausal symptoms.METHODOLOGY: A randomized, single blind, four arm, parallel assignment study was conducted in VMMC and SJH, New Delhi, India. 200 Indian menopausal women were recruited
PMID 26884352

Estrogen and progestogen inhibit NF-κB in atherosclerotic tissues of ovariectomized ApoE (-/-) mice.

Chen Y1, Zhao H2, Ren X3.
Climacteric : the journal of the International Menopause Society.Climacteric.2016 May 3:1-7. [Epub ahead of print]
OBJECTIVES: To determine the effects of estrogen and progestogen treatment on atherosclerotic inflammation and vascular remodeling.METHODS: Atherosclerosis was induced by feeding ovariectomized ApoE (-/-) mice a cholesterol-rich diet. Estrogen and progestogen were supplied as estradiol valerate (E2V
PMID 27138353

Bleeding pattern and cycle control with estetrol-containing combined oral contraceptives: results from a phase II, randomised, dose-finding study (FIESTA).

Apter D1, Zimmerman Y2, Beekman L2, Mawet M3, Maillard C4, Foidart JM5, Coelingh Bennink HJ2.
Contraception.Contraception.2016 May 3. pii: S0010-7824(16)30050-6. doi: 10.1016/j.contraception.2016.04.015. [Epub ahead of print]
OBJECTIVES: This study aims to assess vaginal bleeding patterns and cycle control of oral contraceptives containing estetrol (E4) combined with either drospirenone (DRSP) or levonorgestrel (LNG).STUDY DESIGN: An open-label, multicentre, randomised, dose-finding study lasting six cycles in healthy wo
PMID 27153745

Japanese Journal

Simultaneous Determination of Estradiol Valerate and Medroxyprogesterone Acetate in a Tablet Formulation by Gas Chromatography-Mass Spectrometry

Yilmaz Bilal
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 26(3), 391-393, 2010-03-10
NAID 10026782665

Simultaneous Determination of Estradiol Valerate and Medroxyprogesterone Acetate in a Tablet Formulation by Gas Chromatography-Mass Spectrometry

Analytical Sciences 26(3), 391-393, 2010
… A new and simple gas chromatography–mass spectrometry (GC-MS) method has been developed for simultaneous determination of estradiol valerate (EV) and medroxyprogesterone acetate (MPA) in a tablet formulation. …
NAID 130004441965

Effect of Estrogen on Pressor Responses to .ALPHA.1-Adrenoreceptor Agonist in Conscious Female Rats.

, , , , ,
Hypertension Research 25(4), 609-613, 2002
… At the age of 15 weeks, ovariectomized (OVX) rats received intramuscular injection of estradiol valerate (EV) 5μg (OVX+EV 5μg group; …
NAID 130004436999

「エストラジオール」

Estradiol valerate
Systematic (IUPAC) name
	(17β)-3-hydroxyestra-1,3,5(10)-trien-17-yl valerate
Clinical data
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral, IM
Identifiers
CAS number	979-32-8
ATC code	None
PubChem	CID 13791
ChemSpider	13194
Synonyms	17β-Estradiol-17-valerate pentanoate d'estra-1,3,5(10)-triène-3-ol-17β-yle
Chemical data
Formula	C23H32O3
Mol. mass	356.498 g/mol
	SMILES O=C(O[C@H]3CC[C@H]4[C@H]2[C@@H](c1ccc(O)cc1CC2)CC[C@]34C)CCCC;
	InChI InChI=1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3/t18-,19-,20+,21+,23+/m1/s1; Key:RSEPBGGWRJCQGY-RBRWEJTLSA-N ;