出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/06/14 16:51:19」(JST)
Endoscopic retrograde cholangiopancreatography | |
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Intervention | |
Duodenoscopic image of two pigment stones extracted from common bile duct after sphincterotomy. |
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ICD-9-CM | 51.10 |
MeSH | D002760 |
OPS-301 code: | 1-642 |
Endoscopic retrograde cholangiopancreatography (ERCP) is a technique that combines the use of endoscopy and fluoroscopy to diagnose and treat certain problems of the biliary or pancreatic ductal systems. Through the endoscope, the physician can see the inside of the stomach and duodenum, and inject radiographic contrast into the ducts in the biliary tree and pancreas so they can be seen on X-rays.
ERCP is used primarily to diagnose and treat conditions of the bile ducts and main pancreatic duct,[1] including gallstones, inflammatory strictures (scars), leaks (from trauma and surgery), and cancer. ERCP can be performed for diagnostic and therapeutic reasons, although the development of safer and relatively non-invasive investigations such as magnetic resonance cholangiopancreatography (MRCP) and endoscopic ultrasound has meant that ERCP is now rarely performed without therapeutic intent.
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The patient is sedated or anaesthetized. Then a flexible camera (endoscope) is inserted through the mouth, down the esophagus, into the stomach, through the pylorus into the duodenum where the ampulla of Vater (the opening of the common bile duct and pancreatic duct) exists. The sphincter of Oddi is a muscular valve that controls the opening of the ampulla. The region can be directly visualized with the endoscopic camera while various procedures are performed. A plastic catheter or cannula is inserted through the ampulla, and radiocontrast is injected into the bile ducts and/or pancreatic duct. Fluoroscopy is used to look for blockages, or other lesions such as stones.
When needed, the opening of the ampulla can be enlarged (sphincterotomy) with an electrified wire (sphincterotome) and access into the bile duct obtained so that gallstones may be removed or other therapy performed.
Other procedures associated with ERCP include the trawling of the common bile duct with a basket or balloon to remove gallstones and the insertion of a plastic stent to assist the drainage of bile. Also, the pancreatic duct can be cannulated and stents be inserted. The pancreatic duct requires visualisation in cases of pancreatitis.
In specific cases, a second camera can be inserted through the channel of the first endoscope. This is termed duodenoscope-assisted cholangiopancreatoscopy (DACP) or mother-daughter ERCP. The daughter scope can be used to administer direct electrohydraulic lithotripsy to break up stones, or to help in diagnosis by directly visualizing the duct (as opposed to obtaining X-ray images).[2]
The gallbladder should be surgically removed (cholecystectomy) following successful removal of gallstones from the bile ducts.[3]
The major risk of an ERCP is the development of pancreatitis, which can occur in up to 5% of all procedures. This may be self limited and mild, but may require hospitalization, and rarely, may be life-threatening. Patients at additional risk for pancreatitis are younger patients, patients with previous post-ERCP pancreatitis, females, procedures that involve cannulation or injection of the pancreatic duct, and patients with sphincter of Oddi dysfunction.[4]
Gut perforation is a risk of any endoscopic procedure, and is an additional risk if a sphincterotomy is performed. As the second part of the duodenum is anatomically in a retroperitoneal location (that is, behind the peritoneal structures of the abdomen), perforations due to sphincterotomies are also retroperitoneal. Sphincterotomy is also associated with a risk of bleeding.[4]
Oversedation can result in dangerously low blood pressure, respiratory depression, nausea, and vomiting.
There is also a risk associated with the contrast dye in patients who are allergic to compounds containing iodine.
Other complications (less than 1 per 100) may include; heart and lung problems, bleeding after sphincterotomy, infection in the bile duct (cholangitis) and perforation (a tear in the intestine). In some rare cases, ERCP can even cause fatal complications.[5]
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リンク元 | 「内視鏡的逆行性胆管膵管造影」「内視鏡的逆行性胆膵管造影」「内視鏡的逆行性胆膵管造影法」「内視鏡的逆行性胆道膵管撮影」「ERCP」 |
関連記事 | 「endoscopic」「retrograde」「cholangiopancreatography」 |
内視鏡的逆行性膵胆管造影法 : 約 2,250 件 内視鏡的逆行性膵胆管造影 : 約 33,400 件 内視鏡的逆行性胆管膵管造影法 : 約 13,800 件 内視鏡的逆行性胆管膵管造影 : 約 36,300 件 endoscopic retrograde cholangiopancreatography : 約 120,000 件 endoscopic retrograde cholangio-pancreatography : 約 27,000 件 endoscopic retrograde cholangiopancreagraphy : 4 件
適応 | 禁忌 | 要注意 | |
膵臓疾患 | ・膵臓癌 ・嚢胞性疾患 ・慢性膵炎 ・膵管癒合不全 ・輪状膵 |
・全身状態が著しく不良 ・造影剤過敏症 (アナフィラキシーショック) ・急性膵炎急性期 ・慢性膵炎の急性増悪期 |
・上部消化管狭窄 ・胃全摘出後 Roux-en-Y吻合 ・Billroth II法 残胃例 |
胆道疾患 | ・胆管癌 ・胆嚢癌 ・胆道結石症 ・胆管狭窄 ・膵・胆管合流異常 | ||
乳頭部疾患 | ・乳頭部癌 ・乳頭機能不全症 |
-ERCP
[★] 内視鏡的逆行性胆管膵管造影 endoscopic retrograde cholangiopancreatography
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