antidromic

• 逆行性の、逆行的な、逆方向性の

関

antidromically、retrograde、retrogradely

　

WordNet

1. conducting nerve impulses in a direction opposite to normal
2. of amnesia; affecting time immediately preceding trauma
3. go back over; "retrograde arguments" (同)rehash, hash over
4. move back; "The glacier retrogrades" (同)retreat
5. going from better to worse (同)retrogressive
6. move backward in an orbit, of celestial bodies
7. move in a direction contrary to the usual one; "retrograding planets"
8. moving from east to west on the celestial sphere; or--for planets--around the sun in a direction opposite to that of the Earth

PrepTutorEJDIC

1. 後戻りする,後退する / 悪化する / (生物が)退化する / 後退する,逆行する / 悪くなる / 〈生物が〉退化する

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2019/05/20 19:06:29」(JST)

wiki en

[Wiki en表示]

An antidromic impulse in an axon refers to conduction opposite of the normal (orthodromic) direction. That is, it refers to conduction along the axon away from the axon terminal(s) and towards the soma. For most neurons, their dendrites, soma, or axons are depolarized forming an action potential that moves from the starting point of the depolarization (near the cell body) along the axons of the neuron (orthodromic). Antidromic activation is often induced experimentally by direct electrical stimulation of a presumed target structure. Antidromic ( cell theory) activation is often used in a laboratory setting to confirm that a neuron being recorded from projects to the structure of interest.

See also

• Orthodromic
• Neuron
• Dendrite
• Axon
• Action potential

UpToDate Contents

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• 1. 副伝導路が関与する房室回帰性頻拍（AVRT） atrioventricular reentrant tachycardia avrt associated with an accessory pathway
• 2. ウォルフ・パーキンソン・ホワイト症候群（WPW症候群）に伴う症候性不整脈の治療 treatment of symptomatic arrhythmias associated with the wolff parkinson white syndrome
• 3. 頻脈性不整脈の急性期マネージメントの概要 overview of the acute management of tachyarrhythmias
• 4. QRS幅の広い頻脈の診断のアプローチ approach to the diagnosis of wide qrs complex tachycardias
• 5. Wolff-Parkinson-White症候群の疫学、臨床症状、および診断 epidemiology clinical manifestations and diagnosis of the wolff parkinson white syndrome

English Journal

• Opposing Signaling of ROCK1 and ROCK2 Determines the Switching of Substrate Specificity and the Mode of Migration of Glioblastoma Cells.

• Mertsch S1, Thanos S.Author information 1Institute for Experimental Ophthalmology, School of Medicine, Westfalian-Wilhelms-University Münster, Albert-Schweitzer-Campus 1, D15, 48149, Münster, Germany, sonja.mertsch@ukmuenster.de.AbstractDespite current advances in therapy, the prognosis of patients with glioblastoma has not improved sufficiently in recent decades. This is due mainly to the highly invasive capacity of glioma cells. Little is known about the mechanisms underlying this particular characteristic. While the Rho-kinase (ROCK)-dependent signaling pathways involved in glioma migration have yet to be determined, they show promise as one of the candidates in targeted glioblastoma therapy. There are two ROCK isoforms: ROCK1, which is upregulated in glioblastoma tissue compared to normal brain tissue, and ROCK2, which is also expressed in normal brain tissue. Blockage of both of these ROCK isoforms with pharmacologic inhibitors regulates the migration process. We examined the activities of ROCK1 and ROCK2 using knockdown cell lines and the newly developed stripe assay. Selective knockdown of either ROCK1 or ROCK2 exerted antidromic effects on glioma migration: while ROCK1 deletion altered the substrate-dependent migration, deletion of ROCK2 did not. Furthermore, ROCK1 knockdown reduced cell proliferation, whereas ROCK2 knockdown enhanced it. Along the signaling pathways, key regulators of the ROCK pathway are differentially affected by ROCK1 and ROCK2. These data suggest that the balanced activation of ROCKs is responsible for the substrate-specific migration and the proliferation of glioblastoma cells.
• Molecular neurobiology.Mol Neurobiol.2014 Apr;49(2):900-15. doi: 10.1007/s12035-013-8568-6. Epub 2013 Oct 30.
• Despite current advances in therapy, the prognosis of patients with glioblastoma has not improved sufficiently in recent decades. This is due mainly to the highly invasive capacity of glioma cells. Little is known about the mechanisms underlying this particular characteristic. While the Rho-kinase (
• PMID 24170433

• Antidromic Tachycardia Secondary to Accessory Pathway Ablation.

• Arias MA1, Segovia D2, Pachón M2.
• Revista espanola de cardiologia.Rev Esp Cardiol.2014 Apr;67(4):321. doi: 10.1016/j.recesp.2013.07.006. Epub 2013 Oct 23.
• PMID 24161659

• Is the 12-lead electrocardiogram during antidromic circus movement tachycardia helpful in predicting the ablation site in atriofascicular pathways?

• Sternick EB1, Lokhandwala Y, Bohora S, Timmermans C, Martins PR, Dias LV, Correia FS, Wellens HJ.Author information 1Arrhythmia and Electrophysiology Unit, Biocor Instituto, Nova Lima, Brazil.AbstractAIMS: Unlike in the Wolff-Parkinson-White syndrome, there has been no systematic study on the role of the pre-excitation pattern in predicting the ablation site in patients with atriofascicular (AF) pathways. We assessed in a large cohort the value of the 12-lead electrocardiogram (ECG) during antidromic tachycardia (ADT) to predict the site of ablation.METHODS AND RESULTS: Forty-five patients were studied, 23 males (51%), mean age of 27 ± 12 years with 46 AF pathways and 48 ADT using the AF pathway for A-V conduction. Inclusion required induction of a sustained ADT and successful ablation. Ablation site was assessed during LAO 45° projection and clockwise classified as hours in posteroseptal, posterolateral, lateral, anterolateral, and anteroseptal tricuspid annulus as follows: 05:00-07:00, >07:00-08:00, >08:00-09:00, >09:00-11:00, and >11:00-13:00 o'clock. The QRS axis was assessed during ADT and classified as normal (>+15°), horizontal (+15° to -30°), and superior (<-30°). During ADT axis was superior (-57° ± 10°) in 15 (31%), horizontal (-11° ± 14°) in 22 (46%), and normal (+45° ± 16°) in 11 (23%) patients. The correct ablation site did not differ between the different groups of QRS axis. QRS width during ADT was narrower in patients with a normal when compared with a horizontal and leftward axis (127 ± 14 vs. 145 ± 12 ms, P < 0.0001), and the V-H interval was shorter (4 ± 3 ms vs. 19 ± 22 ms, P = 0.03).CONCLUSIONS: There was no correlation between the AF pathway ablation site and the QRS axis during ADT. The 12-lead ECG during maximal pre-excitation does not predict the proper site of tricuspid annulus ablation in patients with A-V conduction over an AF pathway.
• Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.Europace.2014 Mar 28. [Epub ahead of print]
• AIMS: Unlike in the Wolff-Parkinson-White syndrome, there has been no systematic study on the role of the pre-excitation pattern in predicting the ablation site in patients with atriofascicular (AF) pathways. We assessed in a large cohort the value of the 12-lead electrocardiogram (ECG) during antid
• PMID 24681762

Japanese Journal

• 心室細動からの蘇生後に逆方向性房室回帰性頻拍と稀有型房室結節回帰性頻拍を認めた間歇性WPW症候群の1例

• 心電図 36(3), 187-197, 2016
• NAID 130005519685

• 未経産雌ラットおよび雄ラットの視索上核オキシトシン細胞は対側視索上核から興奮性入力を受ける

• 日本畜産学会報 87(3), 227-233, 2016
• NAID 130005410860

• ATP感受性His束近傍心房頻拍3例の検討

• 心臓 47(SUPPL.2), S2_11-S2_20, 2015
• NAID 130005250927

Related Links

• Antidromic | Definition of Antidromic by Merriam-Webster

1: proceeding or conducting in a direction opposite to the usual one—used especially of a nerve impulse or fiber <antidromic action potentials> 2: characterized by antidromic conduction <antidromic tachycardia in which impulses ...

• antidromicの意味 - goo辞書 英和和英

antidromicとは。意味や和訳。[形容詞] 〔生理〕 逆方向性の：神経線維の興奮が，主に実験的な刺激によって正常とは逆の方向に伝導することについていう. cf. ORTHODROMICantidromically [副詞] - 80万項目以上収録、例文 ...

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★リンクテーブル★

リンク元	「retrograde」「逆行性」「逆方向性」「逆行的」「retrogradely」
拡張検索	「antidromically」「antidromic spike potentia」

「retrograde」

　　[★]

• 逆行性の、逆行型の、逆向性の、逆方向性の

関

antidromic、retrogradely

　 　 　 　 　 　 　 　

「逆行性」

　　[★]

英

retrograde、antidromic、retrogradely

関

逆方向性、逆行的、逆行型、逆向性

「逆方向性」

　　[★]

英

antidromic、retrograde

関

逆行性、逆行的、逆行型、逆向性

「逆行的」

　　[★]

英

antidromic、antidromically

関

逆方向性、逆行性

「retrogradely」

　　[★]

• 逆行性に

関

antidromic、retrograde

「antidromically」

　　[★]

• 逆行的に

関

antidromic

「antidromic spike potentia」

　　[★] 逆方向性スパイク電位