WordNet

acute contagious infection caused by the bacterium Corynebacterium diphtheriae; marked by the formation of a false membrane in the throat and other air passages causing difficulty in breathing
relating to or existing on or affecting the skin; "cutaneous nerves"; "a cutaneous infection" (同)cutaneal, dermal

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/02/12 13:32:19」(JST)

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Baldo BA1.
Drug safety.Drug Saf.2015 May;38(5):455-79. doi: 10.1007/s40264-015-0285-9.
Chimeric fusion proteins, produced by genetic engineering, are currently made up of effector peptides, for example, a ligand-binding portion of a cytokine or growth factor, extracellular domains of lymphocyte antigens, or a toxin linked to a suitable fusion partner. This review covers eight fusion p
PMID 25832756

Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4+ cells in vivo.

Wang Z1, Wei M1, Zhang H1, Chen H1, Germana S1, Huang CA1, Madsen JC2, Sachs DH3, Wang Z4.
Molecular oncology.Mol Oncol.2015 Apr 25. pii: S1574-7891(15)00092-7. doi: 10.1016/j.molonc.2015.04.004. [Epub ahead of print]
CC chemokine receptor 4 (CCR4) has attracted much attention as a promising therapeutic drug target for CCR4+ tumor cells and Tregs. CCR4 is expressed on some tumor cells such as T-cell acute lymphoblastic leukemia (ALL), adult T-cell leukemia/lymphoma (ATLL), adult peripheral T cell lymphoma (PTCL)
PMID 25958791

Cassir N1, Bagnères D2, Fournier PE3, Berbis P4, Brouqui P3, Rossi PM2.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.Int J Infect Dis.2015 Apr;33:104-5. doi: 10.1016/j.ijid.2015.01.008. Epub 2015 Jan 12.
PMID 25592114

Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling.

Nakajima Saeko,Igyártó Botond Z,Honda Tetsuya,Egawa Gyohei,Otsuka Atsushi,Hara-Chikuma Mariko,Watanabe Norihiko,Ziegler Steven F,Tomura Michio,Inaba Kayo,Miyachi Yoshiki,Kaplan Daniel H,Kabashima Kenji
The Journal of allergy and clinical immunology 129(4), 1048-1055.e6, 2012-04
… Background: The clarification of cutaneous dendritic cell subset and the role of thymic stromal lymphopoietin (TSLP) signaling in epicutaneous sensitization with protein antigens, as in the development of atopic dermatitis, is a crucial issue. … Methods: By using Langerin-diphtheria toxin receptor knock-in mice and human Langerin-diphtheria toxin A transgenic mice, we prepared mice deficient in LCs. …
NAID 120004025593

町田裕一,深沢信博,金沢義一
感染症学雑誌 56(7), 552-559, 1982
従来のジフテリア, 百日咳, 破傷風に対する三種混合ワクチン (旧DPTワクチン) と, 改良三種混合ワクチン (改良DPTワクチン) のラットに対するIgE抗体産生能をラヅトhomocytotropic antibodyを指標として比較検討した. 旧DPTワクチン感作ラヅト27例の感作16日後の血清中ジフテリアトキソイド, 破傷風トキソイドに対する抗体陽性率は, それぞれ78% …
NAID 130004328798

VIRULENCE AND IMMUNITY OF CORYNEBACTERIUM DIPHTHERIAE II. EVIDENCE OF THE DIFFERENT MECHANISMS IN THE PROTECTION OF THE CONJUNCTIVAL DIPHTHERIA

広瀬俊一,赤真清人,亀山昭一,村田良介
Japanese Journal of Medical Science and Biology 15(1), 9-17, 1962
… In the previous papers, it was shown that the ability of diphtheria bacilli to develop infection at the mucous membrane varied greatly depending on the strain used and this characteristic was independent not only of thein vitro … Then arose the question of whether the antitoxic immunity alone would be enough to protect the individuals from the infection due to virulent diphtheria bacilli or some other factors would be necessary for complete protection. …
NAID 130003778126