dermal

• adj.

• 皮膚の、経皮の、真皮の、真皮性の

関

corium、cutaneous、cutis、dermis、percutaneous、skin、transdermal、transepidermal

　 　

WordNet

1. of or relating to or located in the dermis (同)dermic
2. bruise, cut, or injure the skin or the surface of; "The boy skinned his knee when he fell" (同)scrape
3. a persons skin regarded as their life; "he tried to save his skin"
4. a bag serving as a container for liquids; it is made from the hide of an animal
5. an outer surface (usually thin); "the skin of an airplane"
6. a natural protective body covering and site of the sense of touch; "your skin is the largest organ of your body" (同)tegument, cutis
7. strip the skin off; "pare apples" (同)peel, pare
8. the deep vascular inner layer of the skin (同)corium, derma
9. through the unbroken skin; refers to medications applied directly to the skin (creams or ointments) or in time-release forms (skin patches); "transdermal estrogen"; "percutaneous absorption" (同)transdermic, percutaneous, transcutaneous
10. relating to or existing on or affecting the skin; "cutaneous nerves"; "a cutaneous infection" (同)cutaneal, dermal
11. of or relating to the hypodermis

PrepTutorEJDIC

1. 皮膚の,皮膚に関する
2. 〈U〉〈C〉(人・動物の)『皮膚』,肌 / 〈C〉〈U〉(動物からはいだ)『皮』,『毛皮』;皮製品,皮袋 / 〈C〉(果物・野菜の)皮 / 〈U〉〈C〉(液体の表面にできる)薄い膜,上皮 / 〈C〉(枠組み・表面などを覆う)外皮,外被,外板 / 〈動物・果物など〉‘の'皮をはぐ(むく) / 〈手・脚など〉‘を'擦りむく / 《話》(金などを)〈人〉‘から'巻き上げる《+『名』〈人〉+『of』+『名』》 / 〈傷口などが〉皮で覆われる《+『over』》
3. =derma
4. 皮膚の,皮膚を冒す
5. 真皮(true skin),皮膚

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/08/27 13:19:33」(JST)

wiki en

[Wiki en表示]

This article is about the layer of skin. For the website, see DermIS (Dermatology Information System).

Dermis
Latin	dermis; corium
Code	TH H3.12.00.1.03001
Anatomical terminology

A graphic representation of the interface between skin epithelium and the underlying connective tissue. Zone B, indicating the region of overlapping projections of epithelium and connective tissue, is the papillary dermis. Zone C, indicating the region of dermis that lies immediately subjacent to the interdigitations of epithelium, is the reticular dermis.

The dermis is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that consists of connective tissue and cushions the body from stress and strain. It is divided into two layers, the superficial area adjacent to the epidermis called the papillary region and a deep thicker area known as the reticular dermis. The dermis is tightly connected to the epidermis through a basement membrane. Structural components of the dermis are collagen, elastic fibers, and extrafibrillar matrix. It also contains Mechanoreceptors that provide the sense of touch and heat, hair follicles, sweat glands, sebaceous glands, apocrine glands, lymphatic vessels and blood vessels. Those blood vessels provide nourishment and waste removal for both dermal and epidermal cells.

Components of the dermis

The dermis is composed of three major types of cells: fibroblasts, macrophages, and adipocytes.

Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan), proteoglycans, and glycoproteins.

Layers

Stratum papillare

The papillary region is composed of loose areolar connective tissue. This is named for its fingerlike projections called papillae, that extend toward the epidermis and contain either terminal networks of blood capillaries or tactile Meissner's corpuscles.

Stratum reticulare

A fluorescent section of blood vessels in the skin; the smooth muscle walls of the blood vessels are brightly stained.

The reticular region lies under the papillary region and is usually much thicker. It is composed of dense irregular connective tissue, and receives its name from the dense concentration of collagenous, elastic, and reticular fibers that weave throughout it. These protein fibers give the dermis its properties of strength, extensibility, and elasticity. Within the reticular region are the roots of the hair, sebaceous glands, sweat glands, receptors, nails, and blood vessels.

Additional images

• Epidermis and dermis of human skin.

• Cross-section of all human skin layers.

• Illustration of Dermal Circulation

See also

• Dermal papillae
• Skin
• Epidermis
• List of cutaneous conditions

References

UpToDate Contents

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• 1. 新生児および乳児における皮膚および頭皮の良性病変 benign skin and scalp lesions in the newborn and young infant
• 2. 黒色腫の病理学的特徴 pathologic characteristics of melanoma
• 3. 色素細胞性母斑（ほくろ）以外の良性色素性皮膚病変 benign pigmented skin lesions other than melanocytic nevi moles
• 4. 色素沈着過剰を有する患者へのアプローチ approach to the patient with hyperpigmentation disorders
• 5. 遺伝性皮膚症 the genodermatoses

English Journal

• Incorporation of antimicrobial peptides on functionalized cotton gauzes for medical applications.

• Gomes AP1, Mano JF2, Queiroz JA3, Gouveia IC4.
• Carbohydrate polymers.Carbohydr Polym.2015 Aug 20;127:451-61. doi: 10.1016/j.carbpol.2015.03.089. Epub 2015 Apr 14.
• A large group of low molecular weight natural compounds that exhibit antimicrobial activity has been isolated from animals and plants during the past two decades. Among them, peptides are the most widespread resulting in a new generation of antimicrobial agents with higher specific activity. In the
• PMID 25965504

• Versatile properties of an exopolysaccharide R-PS18 produced by Rhizobium sp. PRIM-18.

• Priyanka P1, Arun AB1, Ashwini P1, Rekha PD2.
• Carbohydrate polymers.Carbohydr Polym.2015 Aug 1;126:215-21. doi: 10.1016/j.carbpol.2015.03.017. Epub 2015 Mar 17.
• Exopolysaccharides (EPS) produced by bacteria have attracted scientific and industrial attention due to their multifunctional properties and relatively easier production. In this study, an EPS viz., R-PS18 produced by Rhizobium sp. PRIM-18 was characterized and its functional properties were assesse
• PMID 25933542

• Preparation and characterization of cross-linked carboxymethyl chitin porous membrane scaffold for biomedical applications.

• Zhao L1, Wu Y2, Chen S3, Xing T3.
• Carbohydrate polymers.Carbohydr Polym.2015 Aug 1;126:150-5. doi: 10.1016/j.carbpol.2015.02.050. Epub 2015 Mar 5.
• Porous dermal scaffold membrane (PDSM) was successfully prepared by using a so-called sol-gel freeze-drying method. In this method, the carboxymethyl chitin (CMC) hydrosol was first cross-linked by 1-ethyl-3-[3-dimethylaminopropyl] carbodiimide hydrochloride (EDC) and N-hydroxysuccinimide (NHS), and
• PMID 25933533

• Pigment epithelium-derived factor regulates microvascular permeability through adipose triglyceride lipase in sepsis.

• He T1, Hu J2, Yan G3, Li L1, Zhang D1, Zhang Q1, Chen B2, Huang Y1.
• Clinical science (London, England : 1979).Clin Sci (Lond).2015 Jul 1;129(1):49-61. doi: 10.1042/CS20140631.
• The integrity of the vascular barrier, which is essential to blood vessel homoeostasis, can be disrupted by a variety of soluble permeability factors during sepsis. Pigment epithelium-derived factor (PEDF), a potent endogenous anti-angiogenic molecule, is significantly increased in sepsis, but its r
• PMID 25700221

Japanese Journal

• Involvement of the Transporters P-Glycoprotein and Breast Cancer Resistance Protein in Dermal Distribution of the Multikinase Inhibitor Regorafenib and Its Active Metabolites

• Journal of Pharmaceutical Sciences 106(9), 2632-2641, 2017-09-01
• NAID 120006336017

• 経験と考察 高齢者におけるブプレノルフィン経皮吸収型製剤の短期的効果と安全性

• 整形外科 = Orthopedic surgery 68(9), 963-966, 2017-08
• NAID 40021281312

• 線維芽細胞の核膜異常によるシワ発症のメカニズム (特集 シワ発生のメカニズムとその制御)

• Fragrance journal : Research & development for cosmetics, toiletries & allied industries = フレグランスジャーナル : 香粧品科学研究開発専門誌 45(6), 60-65, 2017-06
• NAID 40021244152

• シワ形成における基底膜ヘパラン硫酸の変化とその制御 (特集 シワ発生のメカニズムとその制御)

• Fragrance journal : Research & development for cosmetics, toiletries & allied industries = フレグランスジャーナル : 香粧品科学研究開発専門誌 45(6), 45-48, 2017-06
• NAID 40021244102

Related Links

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• マスク - DERMAL JAPAN

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★リンクテーブル★

リンク元	「transdermal」「percutaneous」「経皮」「cutaneous」「cutis」
拡張検索	「epidermal growth factor receptor gene」「yolk sac endodermal」「cranioectodermal dysplasia 1」「toxic epidermal necrolysis」

「transdermal」

　　[★]

• adj.

• 経皮性の、経皮的な、経皮の

関

dermal、dermally、percutaneous、percutaneously、transcutaneous、transcutaneously、transdermally、transepidermal

　

「percutaneous」

　　[★]

• adj.

• 経皮的な、経皮の

関

dermal、dermally、percutaneously、transcutaneous、transcutaneously、transdermal、transdermally、transepidermal

「経皮」

　　[★]

英

percutaneous、dermal、transdermal、transepidermal

関

経皮的、真皮、真皮性、皮膚、経皮性

「cutaneous」

　　[★]

• adj.

• 皮膚の、皮膚性の

関

cutaneously、cutis、dermal、skin

　 　

「cutis」

　　[★]

• n.

• 真皮、皮膚

関

corium、cutaneous、dermal、dermis、skin

「epidermal growth factor receptor gene」

　　[★]

• 上皮増殖因子受容体遺伝子、上皮成長因子受容体遺伝子、上皮細胞成長因子受容体遺伝子

関

EGFR gene

「yolk sac endodermal」

　　[★]

• 卵黄内胚葉の

関

yolk sac endoderm

「cranioectodermal dysplasia 1」

　　[★] センセンブレナー症候群

「toxic epidermal necrolysis」

　　[★] 中毒性表皮壊死症 TEN