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1. 止血の概要overview of hemostasis [show details]
…mouse model in which the TM gene was ablated was associated with unfettered activation of the coagulation system and widespread thrombosis . Conversely, a naturally-occurring TM mutation (C1611A) that causes …
2. 稀な遺伝性凝固異常rare inherited coagulation disorders [show details]
… affect the coagulation times in vitro. Patients with a more severe coagulation factor deficiency typically have the following laboratory findings Factor XIII – PT and aPTT normal; clot solubility… bleeding) Grade III: spontaneous major bleeding (eg, umbilical, intramuscular, joint, central nervous system, gastrointestinal) Frequent, severe, or chronic bleeding can lead to anemia and iron deficiency…
3. アンチトロンビン欠乏症antithrombin deficiency [show details]
…converts AT from a slow inactivator of coagulation factors such as thrombin (factor IIa) to a rapid inactivator (1000-fold increase in AT activity) ; the specific coagulation factor(s) affected depend on the …
4. 電気外科療法の概要overview of electrosurgery [show details]
… impedance monitor with visual and audible tissue impedance indicators. The system has two different modes, the vapor-pulse coagulation mode and the PlasmaKinetic tissue-cutting mode. In the vapor-pulse mode …
5. 凝固検査の臨床使用clinical use of coagulation tests [show details]
… Several tests of the coagulation system are available, including the prothrombin time (PT), activated partial thromboplastin time (aPTT), and others; these may be ordered in a variety of clinical settings …

English Journal

Clinical observation and management of COVID-19 patients.

Li T, Lu H, Zhang W.
Emerging microbes & infections. 2020 Dec;9(1)687-690.
Three leading infectious disease experts in China were invited to share their bedside observations in the management of COVID-19 patients. Professor Taisheng Li was sent to Wuhan to provide frontline medical care. He depicts the clinical course of SARS-CoV-2 infection. Furthermore, he observes the s
PMID 32208840

Safety Analysis of 13 Suspicious Deaths in Intensive Care: Ergonomics and Forensic Approach Compared.

Tartaglia R, Prineas S, Poli D, Albolino S, Bellandi T, Biancofiore G, Bertolini G, Toccafondi G.
Journal of patient safety. 2020 Mar;().
Thirteen suspicious deaths occurred in an intensive care unit of Tuscany, Italy, in 2015. All patients developed sudden unexplained coagulopathy leading to severe bleeding. None of them had been prescribed heparin, but supertherapeutic concentrations of heparin were found. After a nurse was arrested
PMID 32168278

Combination of Preoperative Plasma Fibrinogen and Neutrophil-to-Lymphocyte Ratio (the F-NLR Score) as a Prognostic Marker of Locally Advanced Rectal Cancer Following Preoperative Chemoradiotherapy.

Sun Y, Zhang Y, Huang Z, Lin H, Lu X, Huang Y, Chi P.
World journal of surgery. 2020 Feb;().
Coagulation and inflammation play important roles in tumor progression. This study aimed to explore the prognostic impact of combined analysis of fibrinogen and neutrophil-to-lymphocyte (NLR) ratio (F-NLR score) in locally advanced rectal cancer (LARC) receiving preoperative chemoradiotherapy (pCRT)
PMID 32020327

Japanese Journal

A Patient with Cavernous Sinus Dural Arteriovenous Fistula Complicating Klippel-Trenaunay Syndrome

Owashi Etsuko,Kato Takayuki,Kokuzawa Jouji,Matsubara Hirofumi,Aki Tatsuki,Shirakami Shin-ichi,Imai Shu
脳神経血管内治療 13(9), 395-401, 2019
… An enlarged subclavian vein and giant varix was detected in the left upper limb, and abnormality of the coagulation-fibrinolysis system caused by localized intravascular coagulation was confirmed. … However, the activation of coagulation-fibrinolysis system continued even after the surgery.Conclusion: …
NAID 130007709830

頭蓋顔面外傷における難治性鼻咽頭出血に関する検討 : 外頸動脈領域経カテーテル的塞栓術および外頸動脈結紮術の適応に関する凝固線溶系異常の観点からの考察

谷崎眞輔,村崎岬,狩野謙一,前田重信,石田浩
日本外傷学会雑誌 33(3), 311-318, 2019
頭蓋顔面外傷に伴う鼻咽頭出血では, 外頸動脈領域に対する経カテーテル的動脈塞栓術 (transcatheter arterial embolization, 以下TAE) が必要となることが多い. 頭蓋底骨折, 顔面骨骨折, 頭頸部鋭的損傷いずれかを認めた頭蓋顔面外傷129例のうち, TAEの適応と判断した難治性鼻咽頭出血7例について検討した. 生存群4例では1例のみで重症頭部 …
NAID 130007681807

A Case of Angioedema due to C1 Inhibitor Deficiency Treated Effectively with Lyophilized Human C1-inactivator Concentrate (Berinert® P) for Airway Stenosis

Komita Kaoru,Hamada Masashi,Sekine Motoki,Kaneda Shoji,Yamamoto Hikaru,Okami Kenji,Iida Masahiro
耳鼻咽喉科臨床　補冊 147(0), 56-57, 2016
… C1 inhibitor (C1-INH) is a protein that adjusts complement functions and thereby controls the blood coagulation system, and its qualitative or quantitative abnormality can recurrently produce local edema. …
NAID 130005284495