クリンダマイシン耐性肺炎球菌
WordNet
- impervious to being affected; "resistant to the effects of heat"; "resistant to persuasion"
- respiratory disease characterized by inflammation of the lung parenchyma (excluding the bronchi) with congestion caused by viruses or bacteria or irritants
- spherical Gram-positive bacteria occurring in pairs or chains; cause e.g. scarlet fever and tonsillitis (同)streptococci, strep
PrepTutorEJDIC
- 抵抗力のある;(…に)抵抗する《+『to』+『名』》
- 肺炎
- 連鎖球菌
UpToDate Contents
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English Journal
- In vivo efficacy of ceftaroline fosamil in a methicillin-resistant panton-valentine leukocidin-producing Staphylococcus aureus rabbit pneumonia model.
- Croisier-Bertin D1, Hayez D, Da Silva S, Labrousse D, Biek D, Badiou C, Dumitrescu O, Guerard P, Charles PE, Piroth L, Lina G, Vandenesch F, Chavanet P.
- Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Apr;58(4):1855-61. doi: 10.1128/AAC.01707-13. Epub 2014 Jan 6.
- Ceftaroline, the active metabolite of the prodrug ceftaroline fosamil, is a cephalosporin with broad-spectrum in vitro activity against Gram-positive organisms, including methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant Streptococcus pneumoniae (MDRSP), and common Gram-nega
- PMID 24395236
- [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia].
- Ramos V1, Duarte C2, Díaz A3, Moreno J1.
- Biomédica : revista del Instituto Nacional de Salud.Biomedica.2014 Apr;34 Suppl 1:209-16. doi: 10.1590/S0120-41572014000500023.
- Introduction: Resistance to macrolide antibiotics is increasing in clinical isolates of Streptococcus pneumoniae and is associated with the presence of mobile genetic elements. Objetive: The aim of this study was to determine the distribution of serotypes and transposons among macrolide-resistant in
- PMID 24968052
- Susceptibility of common bacterial respiratory pathogens to antimicrobial agents in outpatients from South Backa District.
- Horvat O, Ukropina MM, Mijatović V, Sabo A.
- Medicinski pregled.Med Pregl.2014 Mar-Apr;67(3-4):71-7.
- INTRODUCTION: Acute infections of the upper respiratory tract are the most common reasons why patients visit general practitioners. Overuse of antibiotics in treatment of these conditions is extremely common practice although these infections are most frequently caused by viruses. The aim of this st
- PMID 24961047
Japanese Journal
- 当院における主要グラム陽性菌６菌種の薬剤感受性の過去５年間の年次動向：１９９９－２００３
- 横山 琢磨,西 圭史,岡崎 充宏,和田 裕雄,石井 晴之,武田 英紀,渡邉 秀裕,青島 正大,永井 茂,渡邊 卓,後藤 元
- 杏林医学会雑誌 38(1), 11-20, 2007
- … 優れた抗菌力と幅広いスペクトルを有する抗菌薬が登場する一方で，methicillin-resistant <I>Staphylococcus aureus</I>（MRSA）やvancomycin-resistant enterococci（VRE）などの多剤耐性菌の増加が報告されている。 …
- NAID 130000135242
- 耐性機構の多様性を示すマクロライド耐性肺炎球菌分離小児市中肺炎症例に対する azithromycin の臨床効果
- 成相 昭吉,沖津 尚弘,井上 松久
- 感染症学雑誌 : 日本伝染病学会機関誌 : the journal of the Japanese Association for Infectious Diseases 78(6), 490-495, 2004-06-20
- NAID 10013663105
- Phenotypic Differentiation of Macrolide Resistance among Streptococcus pneumoniae Carrying mefA and/or ermB Genes
- Kaieda Satoru,Yano Hisakazu,Okitsu Naohiro,Hosaka Yoshio,Okamoto Ryoichi,Inoue Matsuhisa,Takahashi Haruo
- Acta medica Nagasakiensia 49(1/2), 19-24, 2004-06
- … We examined whether 55 isolates of erythromycin-resistant Streptococcus pneumoniae (MIC?1 μg/mL) carrying mefA and/or ermB genes would develop resistance to telithromycin. … Of the other 40 isolates, 25 carried the ermB gene and 15 carried the both mefA and ermB genes, all of them showed high resistance to clindamycin (MIC?128 μg/mL) and were resistant to macrolides, lincosamides and streptogramin B (MLSB resistance phenotype). …
- NAID 110000939710
Related Links
- Clindamycin-resistant Streptococcus pneumoniae. To the Editor: Antimicrobial medications classified as macrolides (e.g., erythromycin) and lincosamides (e.g., clindamycin) show strong activity against streptococci and are commonly used to treat community-acquired infections caused by Streptococcus pneumoniae.
- (e.g., clindamycin) show strong ac-tivity against streptococci and are commonly used to treat community-acquired infections caused by Strepto-coccus pneumoniae. Moreover, these drugs are the recommended alterna-tives for S.
- Clindamycin-resistant Streptococcus pneumoniae. Montagnani F, Zanchi A, Stolzuoli L, Croci L, Cellesi C. PMCID: PMC2738449 PMID: 18044053 [PubMed - indexed for MEDLINE] Publication Types: Case Reports Letter
★リンクテーブル★
[★]
- 英
- clindamycin resistant Streptococcus pneumoniae
[★]
- ラ
- Streptococcus pneumoniae
- 同
- 肺炎球菌、肺炎レンサ球菌、肺炎連鎖球菌、肺炎双球菌、ストレプトコッカス・ニューモニエ
- 関
- 連鎖球菌
- first aid step1 2006 p.134,138
細菌学
- グラム陽性球菌
- 西洋槍(ランセット)型の双球菌
- α溶血性。ランスフィールド分類には分類されない
- オプトヒン感受性
- 自己融解 autolysis ← 培養しすぎに注意
- 中心部の陥凹した集落
- 莢膜多糖体を有する ← 抗食菌作用(C3bの付着に抵抗する)
- IgA proteaseを分泌
- 健常人の5-250%の気道に存在するが莢膜がない弱毒の株
感染症
-
易感染性宿主
- 2歳以下の乳幼児や老人で重症化しやすい
- 脾臓を受けた患者、急性骨髄性白血病、骨髄移植、HIV感染症で発症しやすい
most common cause of:
MOPS are Most OPtochin Sensitive
診断
- 臨床像から疑い、胸部X線、喀痰のグラム染色、尿中抗原を行う。グラム染色と尿中抗原が陽性であれば特異的な治療を開始する。 (IRE.1010)
- (経験的治療の前に？)診断及び感受性検査のために喀痰培養、血液培養検査を行う。
参考
USMLE
[★]
- 関
- recalcitrance、refractory、resist、resistance、resistive、stand、tolerance、tolerant、withstand
[★]
Streptococcus pneumoniae、Klebsiella pneumoniae、Mycoplasma pneumoniae、Chlamydia pneumoniae、Chlamydophila pneumoniae
[★]
クリンダマイシン
- 同
- Cleocin