中枢神経系ループス血管炎

WordNet

(physical chemistry) a sample of matter in which substances in different phases are in equilibrium; "in a static system oil cannot be replaced by water on a surface"; "a system generating hydrogen peroxide"
instrumentality that combines interrelated interacting artifacts designed to work as a coherent entity; "he bought a new stereo system"; "the system consists of a motor and a small computer"
a group of independent but interrelated elements comprising a unified whole; "a vast system of production and distribution and consumption keep the country going" (同)scheme
a complex of methods or rules governing behavior; "they have to operate under a system they oppose"; "that language has a complex system for indicating gender" (同)system of rules
a group of physiologically or anatomically related organs or parts; "the body has a system of organs for digestion"
a procedure or process for obtaining an objective; "they had to devise a system that did not depend on cooperation"
the living body considered as made up of interdependent components forming a unified whole; "exercise helped him get the alcohol out of his system"
in or near a center or constituting a center; the inner area; "a central position"
a workplace that serves as a telecommunications facility where lines from telephones can be connected together to permit communication (同)telephone exchange, exchange
easily agitated; "a nervous addict"; "a nervous thoroughbred"
of or relating to the nervous system; "nervous disease"; "neural disorder" (同)neural
any of several forms of ulcerative skin disease
a constellation in the southern hemisphere near Centaurus

PrepTutorEJDIC

〈C〉(関連した部分から成る)『体系』,系統,組織[網],装置 / 〈C〉(教育・政治などの)『制度』,機構;《the~》体制 / 〈C〉(思想・学問などの)『体系』,学説 / 〈C〉(…の)『方法』,方式,やり方《+of doing》 / 〈U〉正しい方針(筋道,順序) / 〈U〉《the~》(身体の)組織,系統 / 〈U〉《the~,one's~》身体,全身
『中心の』,中央の,中心からの / 『主要な』,中心的な(main) / (音声が)中舌音の / 電話交換局(《英》[telephone]exchange)
『神経の』 / 『神経質な』,神経過敏な / 『心配な』,不安な
狼瘡(ろうそう)(皮膚結核の一種)

UpToDate Contents

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1. 全身性エリテマトーデスの神経症状 neurologic manifestations of systemic lupus erythematosus
2. 全身性エリテマトーデスの神経精神症状に対する診断的アプローチ diagnostic approach to the neuropsychiatric manifestations of systemic lupus erythematosus
3. 血管炎の消化器症状 gastrointestinal manifestations of vasculitis
4. 成人における中枢神経系の原発性血管炎 primary angiitis of the central nervous system in adults
5. 全身性エリテマトーデスの筋骨格系症状 musculoskeletal manifestations of systemic lupus erythematosus

English Journal

Identification of a pathogenic variant in TREX1 in early-onset cerebral systemic lupus erythematosus by Whole-exome sequencing.

Ellyard JI, Jerjen R, Martin JL, Lee AY, Field MA, Jiang SH, Cappello J, Naumann SK, Andrews TD, Scott HS, Casarotto MG, Goodnow CC, Chaitow J, Pascual V, Hertzog P, Alexander SI, Cook MC, Vinuesa CG.
Arthritis & rheumatology (Hoboken, N.J.).Arthritis Rheumatol.2014 Dec;66(12):3382-6.
Objective. Systemic lupus erythematosus (SLE) isa chronic and heterogeneous autoimmune disease. Both twin and sibling studies indicate a strong genetic contribution to lupus, but in the majority of cases the pathogenic variant remains to be identified. The genetic contribution to disease is likely t
PMID 25138095

Participation of the neutrophin brain-derived neurotrophic factor in neuropsychiatric systemic lupus erythematosus.

Tamashiro LF1, Oliveira RD1, Oliveira R1, Frota ER2, Donadi EA1, Del-Ben CM2, Teixeira AL2, Louzada-Junior P3.
Rheumatology (Oxford, England).Rheumatology (Oxford).2014 Dec;53(12):2182-90. doi: 10.1093/rheumatology/keu251. Epub 2014 Jun 18.
OBJECTIVE: Brain-derived neurotrophic factor (BDNF) is associated with the pathogenesis of several neuropsychiatric (NP) diseases, but there are few studies involving SLE. The aim of this study was to investigate whether plasma BDNF levels are associated with disease activity in SLE patients with se
PMID 24942492

Cerebral large vessel vasculitis in systemic lupus erythematosus.

Böckle BC1, Jara D2, Aichhorn K3, Junker D4, Berger T5, Ratzinger G3, Sepp NT6.
Lupus.Lupus.2014 Nov;23(13):1417-21. doi: 10.1177/0961203314541689. Epub 2014 Jun 26.
Neuropsychiatric systemic lupus erythematosus (NPSLE) is defined by involvement of the central nervous system in systemic lupus erythematosus (SLE), with a wide range of both neurological and psychiatric manifestations. Although its aetiopathogenesis is not fully elucidated, NPSLE seems to be a cons
PMID 24969082

Japanese Journal

中枢神経病変

廣畑俊成
日本臨床免疫学会会誌 = Japanese journal of clinical immunology 27(3), 109-117, 2004-06-30
膠原病および膠原病類縁疾患においてはしばしば中枢神経病変の合併が見られる. 全身性エリテマトーデス (SLE) における中枢神経病変 (いわゆるCNSループス) においては, 中枢神経内での免疫異常が重要な役割を果たすことが明らかにされている. すなわち, 中枢神経内での免疫グロブリン産生の指標であるCSF Ig indexや髄液中のIL-6やIFN-αは, CNSループスの患者において上昇してい …
NAID 10013517264

重篤なSLE網膜症を示した中枢神経ループスの3例

下長野由佳,鵜木滋子,速見佳代子 [他],鵜木一彦,坂本泰二
あたらしい眼科 = Journal of the eye 20(9), 1323-1327, 2003-09-30
NAID 10017017957

再発性横断性脊髄炎を呈し, 抗神経抗体を認めた慢性関節リウマチに随伴したシェーグレン症候群の1例

藤本陽子,荒井完周,石田和之,横田隆徳,柳沼将公,村瀬弘
日本臨床免疫学会会誌 = Japanese journal of clinical immunology 18(1), 76-82, 1995-02-28
… She had no symptom of systemic vasculitis. … Lupus anticoagulant and anticaldiolipin antibody were negative. … Vasculitis and the immunological reaction of antineuronal antibody have been suggested as possible causes. … This report suggests the influence of direct immunological reaction on the central nervous system. …
NAID 10005513355