ビチオノール
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/06/19 09:42:32」(JST)
[Wiki en表示]
Bithionol
|
Systematic (IUPAC) name |
2,2'-sulfanediylbis(4,6-dichlorophenol) |
Clinical data |
Pregnancy cat. |
? |
Legal status |
? |
Identifiers |
CAS number |
97-18-7 N |
ATC code |
D10AB01 P02BX01 QP52AG07 |
PubChem |
CID 2406 |
IUPHAR ligand |
2338 |
DrugBank |
DB04813 |
ChemSpider |
2313 Y |
UNII |
AMT77LS62O Y |
ChEBI |
CHEBI:3131 Y |
ChEMBL |
CHEMBL290106 Y |
Synonyms |
2,4-dichloro- 6-(3,5-dichloro- 2-hydroxyphenyl)sulfanylphenol |
Chemical data |
Formula |
C12H6Cl4O2S |
Mol. mass |
356.05 g/mol |
InChI
-
InChI=1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H Y
Key:JFIOVJDNOJYLKP-UHFFFAOYSA-N Y
|
N (what is this?) (verify)
|
Bithionol is an anthelmintic used to treat Fasciola hepatica (liver flukes).
References
Antiparasitics – Anthelmintics (P02)
|
|
Antiplatyhelmintic agents |
Antitrematodals
(schistosomicides)
|
Binds tubulin
|
- benzimidazole (Triclabendazole#)
|
|
AI
|
- phosphonic acid (Metrifonate)
|
|
Other/unknown
|
- quinoline (Praziquantel#
- Oxamniquine#)
- phenol (Bithionol)
- thiazole (Niridazole)
- arylsulfonate (Stibophen)
|
|
|
Anticestodals
(taeniacides)
|
Binds tubulin
|
- benzimidazole (Albendazole#)
|
|
Other/unknown
|
- salicylanilide (Niclosamide)#
- aminoacridine (Quinacrine)
- butyrophenone (Desaspidin)
- chlorophenol (Dichlorophen)
|
|
|
|
Antinematodal agents
(including
macrofilaricides) |
Binds tubulin
|
- benzimidazole (Mebendazole#
- Albendazole#
- Thiabendazole
- Fenbendazole
- Ciclobendazole
- Flubendazole)
|
|
Chloride channel
|
|
|
NMDA
|
- tetrahydropyrimidine (Pyrantel#
- Pyrantel pamoate
- Oxantel)
|
|
Other/unknown
|
- piperazine (Piperazine
- Diethylcarbamazine#)
- thiazole (Levamisole#)
- quinolinium (Pyrvinium)
- benzylammonium (Bephenium)
- naphthalenesulfonate (Suramin#)
- Tribendimidine
|
|
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- Involvement of autotaxin/lysophospholipase D expression in intestinal vessels in aggravation of intestinal damage through lymphocyte migration.
- Hozumi H, Hokari R, Kurihara C, Narimatsu K, Sato H, Sato S, Ueda T, Higashiyama M, Okada Y, Watanabe C, Komoto S, Tomita K, Kawaguchi A, Nagao S, Miura S.SourceInternal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
- Laboratory investigation; a journal of technical methods and pathology.Lab Invest.2013 May;93(5):508-19. doi: 10.1038/labinvest.2013.45. Epub 2013 Mar 11.
- Lysophosphatidic acid (LPA) has a critical role in lymphocyte migration to secondary lymphoid organs. Autotaxin (ATX)/lysophospholipase D, in the vascular endothelium, is the main enzyme involved in LPA production. Whether ATX is involved in pathological lymphocyte migration to the inflamed mucosa h
- PMID 23478591
- A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication.
- Seguin SP, Ireland AW, Gupta T, Wright CM, Miyata Y, Wipf P, Pipas JM, Gestwicki JE, Brodsky JL.SourceDepartment of Biological Science, University of Pittsburgh, Pittsburgh, PA 15260, USA.
- Antiviral research.Antiviral Res.2012 Oct;96(1):70-81. doi: 10.1016/j.antiviral.2012.07.012. Epub 2012 Aug 7.
- New polyomaviruses are continually being identified, and it is likely that links between this virus family and disease will continue to emerge. Unfortunately, a specific treatment for polyomavirus-associated disease is lacking. Because polyomaviruses express large Tumor Antigen, TAg, we hypothesized
- PMID 22898086
- Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2.
- Zocher K, Fritz-Wolf K, Kehr S, Fischer M, Rahlfs S, Becker K.SourceInterdisciplinary Research Center, Justus Liebig University, Heinrich-Buff-Ring 26-32, D-35392 Giessen, Germany. kathleen.zocher@gmx.de
- Molecular and biochemical parasitology.Mol Biochem Parasitol.2012 May;183(1):52-62. doi: 10.1016/j.molbiopara.2012.01.007. Epub 2012 Feb 9.
- Glutamate dehydrogenases (GDHs) play key roles in cellular redox, amino acid, and energy metabolism, thus representing potential targets for pharmacological interventions. Here we studied the functional network provided by the three known glutamate dehydrogenases of the malaria parasite Plasmodium f
- PMID 22342964
Japanese Journal
- 鹿児島県薩摩郡内1地区の牛における双口吸虫感染の実態
- 小野 由樹,久林 朋憲,田村 厚規 [他]
- 牛臨床寄生虫研究会誌 = Japanese journal of clinical bovine parasitology 2(1), 11-14, 2011-07
- NAID 40019361657
- Evaluation of Marked Rise in Fecal Egg Output after Bithionol Administration to Horse and its Application as a Diagnostic Marker for Equine Anoplocephala perfoliata Infection
- SANADA Yoshinori,SENBA Hiroyuki,MOCHIZUKI Rieko,ARAKAKI Hidemi,GOTOH Tadahiro,FUKUMOTO Shin-ichiro,NAGAHATA Hajime
- Journal of Veterinary Medical Science 71(5), 617-620, 2009
- … To establish a reliable diagnostic measure for equine Anoplocephala perfoliata infection, the impact of deworming was examined in 12 Thoroughbreds to which bithionol (5-10 mg/kg body weight) was administered and feces were examined by the modified Wisconsin method using sucrose solution. … The optimum time for post-deworming egg detection was examined in following horses: 17 mares were administered bithionol and 10 mares were used as controls. …
- NAID 130000134373
Related Links
- Bithionol. From Wikipedia, the free encyclopedia. Jump to: navigation, search. Bithionol. Systematic (IUPAC) name ... Y. N (what is this?) (verify). Bithionol is an anthelmintic used to treat Fasciola hepatica (liver flukes). [edit] References. v · t · e ...
Related Pictures
★リンクテーブル★
[★]
- 英
- anthelmintic, anthelmintics
- ラ
- anthelmintica
- 関