M-VAC regimen

M-VAC療法

WordNet

1. (medicine) a systematic plan for therapy (often including diet) (同)regime
2. the 22nd letter of the Roman alphabet (同)v
3. the 13th letter of the Roman alphabet (同)m

PrepTutorEJDIC

1. 摂生,養生[法],健康法,食事療法
2. 政治体制;制度 / =regimen
3. Veterans Administration 在郷軍人局 / Vice Admiral
4. vanadium の化学記号
5. Mach number / mark[s] / Monsieur

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English Journal

• Retrospective analysis of the efficacy of two cycles of M-VAC neoadjuvant chemotherapy followed by radical cystectomy for muscle-invasive bladder cancer.

• Kitagawa Y1, Izumi K, Miwa S, Kadono Y, Konaka H, Mizokami A, Namiki M.Author information 1Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Takaramachi 13-1, Kanazawa, Ishikawa, Japan. yasukita@med.kanazawa-u.ac.jp.AbstractBACKGROUND: Neoadjuvant chemotherapy before radical cystectomy for muscle-invasive bladder cancer is a commonly used treatment modality. However, in terms of chemotherapeutic regimens and the number of cycles of neoadjuvant chemotherapy, there is yet no international consensus, as various studies indicate the efficacy of several platinum-based combination chemotherapeutic regimens. We determined the efficacy of two cycles of neoadjuvant chemotherapy with methotrexate, vinblastine, adriamycin, and cisplatin followed by radical cystectomy.
• Anticancer research.Anticancer Res.2013 Oct;33(10):4497-503.
• BACKGROUND: Neoadjuvant chemotherapy before radical cystectomy for muscle-invasive bladder cancer is a commonly used treatment modality. However, in terms of chemotherapeutic regimens and the number of cycles of neoadjuvant chemotherapy, there is yet no international consensus, as various studies in
• PMID 24123021

• Urothelial bladder carcinoma with choriocarcinomatous differentiation presenting with a false-positive pregnancy test.

• Rajabi B1, Khoury J, Brewer C, Goodman OB Jr.Author information 1Division of Medical Oncology, University of Nevada School of Medicine/University of California San Diego Nevada Cancer Institute, Las Vegas, NV 89135, USA. brajabi@medicine.nevada.eduAbstractUrothelial carcinoma of the bladder with choriocarcinomatous features is a rare presentation among genitourinary cancers. In this study, the case of a 42-year-old woman who presented with menstrual irregularity and positive urine and serum beta-human chorionic gonadotropin tests is presented. Pelvic ultrasound showed no intrauterine pregnancy. Laparoscopy and hysteroscopy with dilatation and curettage were negative for evidence of trophoblastic tissue. Computed tomography of the abdomen and pelvis showed an intravesical fundal mass, with no evidence of extravesical disease. Cystoscopy and transurethral resection of the bladder tumor diagnosed an invasive high-grade urothelial carcinoma with trophoblastic differentiation and multiple foci of choriocarcinomatous morphology. The patient received 3 cycles of neoadjuvant chemotherapy with methotrexate, vinblastine, adriamycin and cisplatin and then underwent partial cystectomy, which was negative for any residual tumor. This is the first reported case of a positive urine pregnancy test leading to the diagnosis of urothelial carcinoma.
• The American journal of the medical sciences.Am J Med Sci.2013 Sep;346(3):256-8. doi: 10.1097/MAJ.0b013e318270d0f9.
• Urothelial carcinoma of the bladder with choriocarcinomatous features is a rare presentation among genitourinary cancers. In this study, the case of a 42-year-old woman who presented with menstrual irregularity and positive urine and serum beta-human chorionic gonadotropin tests is presented. Pelvic
• PMID 23147379

• Prospective, open-label, randomized, phase III study of two dose-dense regimens MVAC versus gemcitabine/cisplatin in patients with inoperable, metastatic or relapsed urothelial cancer: a Hellenic Cooperative Oncology Group study (HE 16/03).

• Bamias A1, Dafni U, Karadimou A, Timotheadou E, Aravantinos G, Psyrri A, Xanthakis I, Tsiatas M, Koutoulidis V, Constantinidis C, Hatzimouratidis C, Samantas E, Visvikis A, Chrisophos M, Stravodimos K, Deliveliotis C, Eleftheraki A, Pectasides D, Fountzilas G, Dimopoulos MA.Author information 1Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece. abamias@med.uoa.grAbstractBACKGROUND: The combinations of methotrexate, vinblastine, Adriamycin, cisplatin (Pharmanell, Athens, Greece) (MVAC) or gemcitabine, cisplatin (GC) represent the standard treatment of advanced urothelial cancer (UC). Dose-dense (DD)-MVAC has achieved longer progression-free survival (PFS) than the conventional MVAC. However, the role of GC intensification has not been studied. We conducted a randomized, phase III study comparing a DD-GC regimen with DD-MVAC in advanced UC.
• Annals of oncology : official journal of the European Society for Medical Oncology / ESMO.Ann Oncol.2013 Apr;24(4):1011-7. doi: 10.1093/annonc/mds583. Epub 2012 Nov 7.
• BACKGROUND: The combinations of methotrexate, vinblastine, Adriamycin, cisplatin (Pharmanell, Athens, Greece) (MVAC) or gemcitabine, cisplatin (GC) represent the standard treatment of advanced urothelial cancer (UC). Dose-dense (DD)-MVAC has achieved longer progression-free survival (PFS) than the c
• PMID 23136231

Japanese Journal

• 進行性尿路上皮癌に対するM-VAC変法療法の成績

• 三浦 徳宣,沼田 幸作,東 浩司,橋根 勝義,住吉 義光
• 日本泌尿器科學會雜誌 98(4), 589-594, 2007-05-20
• … (目的)局所進行,及び転移性尿路上皮癌に対し,M-VAC変法を施行し,その奏効率,奏効期間および有害事象についてretrospectiveに検討した.(対象と方法) 1993年10月から2005年2月までに, M-VAC変法を施行した局所進行及び転移性尿路上皮癌患者28例のうち,評価可能病変を有する25例を対象とした. …
• NAID 110006273452

• 患者の個性を考慮したオーダーメイド医療の実現にむけて - 遺伝子発現情報を用いた浸潤性膀胱癌に対するM-VAC術前化学療法感受性予測システムの構築 -

• 高田 亮,小原 航,藤岡 知昭
• 岩手医学雑誌 58(1), 1-8, 2006-04-01
• NAID 110004623044

Related Links

• M-VAC - Bladder cancer chemotherapy regimen - The ...

RESULTS: As expected, the M-VAC regimen was associated with a greater toxicity, especially leukopenia, mucositis, granulocytopenic fever, and drug-related mortality. Response rates were superior for the M (39% v 12%; P less ...

• タイトル: 進行性尿路上皮癌に対するM-VAC療法 : 副作用とその ...

... cell carcinoma and they received a total of 163 complete courses of M-VAC therapy. We examined the side effects of this M-VAC regimen, and evaluated the effectiveness of colony-stimulating factor for prevention of URI: ...

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★リンクテーブル★

リンク元	「M-VAC療法」
関連記事	「regime」「regimen」「VA」「V」「Md」

「M-VAC療法」

　　[★]

英

M-VAC regimen

関

[[]]

[show details]

M-VAC regimen : 約 16,100 件
M-VAC therapy : 約 13,800 件

• メトトレキサート methotrexate：葉酸代謝拮抗薬
• ドキソルビシン doxorubicin：DNAと複合体形成 = アドリアマイシン adriamycin
• ビンブラスチン vinblastine：チューブリンと結合
• シスプラチン cisplatin：DNAと共有結合

適応

• 膀胱癌

「regime」

　　[★]

• n.

• 政治制度/政治形態、政体。政権、政府。管理体制。その支配期間
• [ regimenと同じ](医)(食事・運動などの規制による)摂生、養生法。厳しい修練
• 社会組織/社会制度。社会秩序。(組織などの)運営体制。
• (梅雨などの)規則的に繰り返される事象。(氷河などの)季節変動型の型

　

「regimen」

　　[★]

• n.

• (食事などの)養生規則、養生計画。(薬の)処方計画、投薬計画

関

action、administration schedule、cure、dosage regimen、dosage schedule、dosing regimen、remedy、therapeutic、therapy

　 　

「VA」

　　[★]

• 椎骨動脈 vertebral artery
• 前腹側核 anteroventral nucleus ventral anterior nucleus
• 肺胞換気量 alveolar ventilation, alveolar ventilation volume

　

「V」

　　[★]

• バリン valine
• ビタミン vitamine
• ventilation

　 　

「Md」

　　[★] メンデレビウム mendelevium