フルボキサミン fluvoxamine
PrepTutorEJDIC
- Florida
English Journal
- Fluoxetine addition to methadone in addicts: pharmacokinetic aspects.
- Bertschy G, Eap CB, Powell K, Baumann P.SourceDépartement Universitaire de Psychiatrie Adulte, Lausanne, Switzerland.
- Therapeutic drug monitoring.Ther Drug Monit.1996 Oct;18(5):570-2.
- We report nine cases where fluoxetine (FX) (20 mg/day) was added to maintenance treatment with methadone (MTD) (dose range: 30-100 mg) in addicts with affective disorders. MTD plasma levels were measured before and after treatment with FX under steady-state conditions. Among the nine patients, two a
- PMID 8885121
- Probable metabolic interaction between methadone and fluvoxamine in addict patients.
- Bertschy G, Baumann P, Eap CB, Baettig D.SourceDépartement Universitaire de Psychiatrie Adulte, Lausanne, Switzerland.
- Therapeutic drug monitoring.Ther Drug Monit.1994 Feb;16(1):42-5.
- We report five cases where fluvoxamine (FLVX) was added to maintenance treatment with methadone (MTD) in addict patients with affective disorders. In view of the implication of FLVX in several metabolic drug interactions, MTD plasma levels were measured before and after treatment with FLVX. A slight
- PMID 8160253
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Related Pictures
★リンクテーブル★
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- 英
- fluvoxamine FLVX
- 化
- マレイン酸フルボキサミン fluvoxamine maleate
- 商
- ルボックス、デプロメール
- 関
- セロトニン、セロトニン受容体
- 精神神経用剤
-
禁忌
副作用
- 安全性評価対象例712例中306例(43.0%)、690件の副作用が認められた。内訳は副作用症状256例(36.0%)、522件、臨床検査値異常86例(12.1%)、168件であった。
- 主なものは嘔気・悪心84件(11.8%)、口渇51件(7.2%)、便秘36件(5.1%)等の消化管障害、眠気69件(9.7%)、めまい21件(2.9%)等の精神神経系障害、怠感23件(3.2%)等の一般的全身障害、ALT(GPT)上昇31件(4.4%)、AST(GOT)上昇20件(2.8%)等の臨床検査値異常であった。(承認時:1999年4月)
添付文書
http://www.info.pmda.go.jp/go/pack/1179039F1036_1_30/
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