- 関
- type I bone morphogenetic protein receptor
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
- the 9th letter of the Roman alphabet (同)i
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- 『私は』私が
- iodineの化学記号
- =sense organ / 受信装置
- basal metabolism基礎代謝
UpToDate Contents
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English Journal
- An Acvr1 R206H knock-in mouse has fibrodysplasia ossificans progressiva.
- Chakkalakal SA, Zhang D, Culbert AL, Convente MR, Caron RJ, Wright AC, Maidment AD, Kaplan FS, Shore EM.SourceDepartment of Orthopaedic Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA; Center for Research in FOP and Related Disorders, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 19104, USA.
- Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.J Bone Miner Res.2012 Aug;27(8):1746-1756. doi: 10.1002/jbmr.1637.
- Fibrodysplasia ossificans progressiva (FOP; MIM #135100) is a debilitating genetic disorder of dysregulated cellular differentiation characterized by malformation of the great toes during embryonic skeletal development and by progressive heterotopic endochondral ossification postnatally. Patients wi
- PMID 22508565
- Inhibition of erythropoiesis by Smad6 in human cord blood hematopoietic stem cells.
- Kang YJ, Shin JW, Yoon JH, Oh IH, Lee SP, Kim SY, Park SH, Mamura M.SourceLaboratory of Immunology, Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Republic of Korea.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2012 Jul 13;423(4):750-6. Epub 2012 Jun 15.
- Bone morphogenetic proteins (BMPs) that belong to the transforming growth factor-β (TGF-β) superfamily cytokines, play crucial roles in hematopoiesis. However, roles of Smad6 in hematopoiesis remained unknown in contrast to the other inhibitory Smad (I-Smad), Smad7. Here we show that Smad6 inhibit
- PMID 22705548
Japanese Journal
- The regulation of hepcidin expression by serum treatment: requirements of the BMP response element and STAT- and AP-1-binding sites.
- Kanamori Yohei,Murakami Masaru,Matsui Tohru,Funaba Masayuki
- Gene 551(2), 119-126, 2014-11-10
- … Expression of hepcidin, a central regulator of systemic iron metabolism, is transcriptionally regulated by the bone morphogenetic protein (BMP) pathway. … However, the factors other than the BMP pathway also participate in the regulation of hepcidin expression. … Co-treatment with LDN-193189, an inhibitor of the BMP type I receptor, abrogated this hepcidin induction. …
- NAID 120005511083
- 〈Original Papers〉Gene cloning and characterization of pearl oyster Pinctada fucata α-tubulin
- Miyashital Tomoyuki,Takami Akiko,Sugimoto Yui,Sakai Ayumi,Takagi Ryosuke
- Memoirs of the Faculty of Biology-Oriented Science and Technology of Kinki University 31, 1-8, 2013-03
- … [Abstract] We have isolated a full-length Pinctada fucata a-tubulin gene that is one of the genes obtained in the process of selecting the BMP (Bone Morphogenetic Protein) type II receptor gene. …
- NAID 120005260074
- Role of matrix metalloproteinase-10 in the BMP-2 inducing osteoblastic differentiation
- , , , , ,
- Endocrine Journal 60(12), 1309-1319, 2013
- … A mutation causing constitutive activation in a bone morphogenetic protein (BMP) type 1 receptor [ALK2(R206H)] is found in most patients with FOP. … MMP-10 significantly augmented the levels of Osterix, type 1 collagen, alkaline phosphatase (ALP) and osteocalcin mRNA as well as ALP activity enhanced by BMP-2 in C2C12 cells. …
- NAID 130004770406
Related Links
- ... joint fusion and functional impairment, thus phenocopying key aspects of human FOP. A selective inhibitor of BMP type I receptor kinases, LDN-193189 (ref. 6), inhibits activation of the BMP signaling effectors SMAD1 1, 2, 4 ...
- 1. Nat Med. 2008 Dec;14(12):1363-9. doi: 10.1038/nm.1888. Epub 2008 Nov 30. BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Yu PB, Deng DY, Lai CS, Hong CC, Cuny GD, Bouxsein ML, Hong DW ...
★リンクテーブル★
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- 英
- type I bone morphogenetic protein receptor、BMP type I receptor
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- 関
- BMP type I receptor
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- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
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- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
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- 関
- basal lamina、basal laminae、basal membrane、basement membrane、bone marrow、myelo、myeloid
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