- 関
- carcinogen、tumor initiator
WordNet
- any substance that produces cancer
- change a pawn for a better piece by advancing it to the eighth row, or change a checker piece for a more valuable piece by moving it to the row closest to your opponent
- contribute to the progress or growth of; "I am promoting the use of computers in the classroom" (同)advance, boost, further, encourage
- give a promotion to or assign to a higher position; "John was kicked upstairs when a replacement was hired"; "Women tend not to advance in the major law firms"; "I got promoted after many years of hard work" (同)upgrade, advance, kick upstairs, raise, elevate
- be changed for a superior chess or checker piece
- someone who is an active supporter and advocate (同)booster, plugger
- an abnormal new mass of tissue that serves no purpose (同)tumour, neoplasm
PrepTutorEJDIC
- 発がん物質,発がん因子
- …‘を'『助長する』,促進する,増進する / (…に)…‘を'『昇進させる』,進級させる《+『名+to+名』》 / 〈議案など〉‘を'通過するように努力する / 〈会社・事業〉‘を'発起する;〈興業〉‘を'主催する / 〈商品など〉‘の'販売促進をする
- (物事の)推進者,奨励者 / (会社の)発起人,創立者 / 興行師,プロモーター;(会などの)主催者
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/10/06 11:48:17」(JST)
[Wiki en表示]
Tumor promotion is a process in carcinogenesis by which various factors permit the descendents of a single initiated cell to survive and expand in number, i.e. to resist apoptosis and to undergo clonal growth. This is a step toward tumor progression[1][2]
In order for a tumor cell to survive, it must decrease its expression of tumor suppressor genes such as p53, BRCA1, BRCA2, RB1 or the fas receptor. [3] [4] A tumor suppressor would trigger an apoptotic pathway in a cancer cell if there were DNA damage, polyploidy, or uncontrolled cell growth.
Simultaneously, tumor cells need to upregulate oncogenes, which promote or cause downstream activation of growth factors and cell survival signals such as Ras, Mitogen-activated protein kinase kinase, VEGF, or Akt. [5]
See also[edit]
- Tumor progression
- Phorbol myristate acetate
References[edit]
- ^ Seth Rakoff-Nahoum (Dec 2006). "Why Cancer and Inflammation?". Yale Journal of Biology and Medicine 79 (3-4): 123–130. PMC 1994795.
- ^ "NCI Dictionary of Cancer Terms:Tumor promotion". National Cancer Institute. Retrieved 10 Nov 2012.
- ^ "Tumor Suppressor Genes".
- ^ "Oncogenes, Tumor Suppressor Genes,and Cancer". American Cancer Society.
- ^ "Oncogenes, Tumor Suppressor Genes,and Cancer". American Cancer Society.
UpToDate Contents
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English Journal
- Gut microbes, diet, and cancer.
- Hullar MA, Burnett-Hartman AN, Lampe JW.SourceCancer Prevention Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave N, M4-B402, PO Box 19024, Seattle, WA, 98109, USA.
- Cancer treatment and research.Cancer Treat Res.2014;159:377-99. doi: 10.1007/978-3-642-38007-5_22.
- An expanding body of evidence supports a role for gut microbes in the etiology of cancer. Previously, the focus was on identifying individual bacterial species that directly initiate or promote gastrointestinal malignancies; however, the capacity of gut microbes to influence systemic inflammation an
- PMID 24114492
- The diet as a cause of human prostate cancer.
- Nelson WG, Demarzo AM, Yegnasubramanian S.SourceDepartments of Oncology, Pathology, and Urology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Weinberg Bldg 1100, 1650 Orleans Street, Baltimore, MD, 21231, USA, bnelson@jhmi.edu.
- Cancer treatment and research.Cancer Treat Res.2014;159:51-68. doi: 10.1007/978-3-642-38007-5_4.
- Asymptomatic prostate inflammation and prostate cancer have reached epidemic proportions among men in the developed world. Animal model studies implicate dietary carcinogens, such as the heterocyclic amines from over-cooked meats and sex steroid hormones, particularly estrogens, as candidate etiolog
- PMID 24114474
- IPS-1 plays a dual function to directly induce apoptosis in murine melanoma cells by inactivated Sendai virus.
- Zhang Q, Xu X, Yuan Y, Gong X, Chen Z, Xu X.SourceComparative Medicine Center, College of Veterinary Medicine, Yangzhou University, Yangzhou, China.
- International journal of cancer. Journal international du cancer.Int J Cancer.2014 Jan 1;134(1):224-34. doi: 10.1002/ijc.28340. Epub 2013 Jul 24.
- Inactivated Sendai virus (HVJ-E) directly kills cancer cells by inducing apoptosis through a mechanism mediated by Janus kinases/signal transducers and activators of transcription (JAK/STAT) signaling pathways. However, whether other signaling pathways are involved remain largely unknown. This study
- PMID 23784981
Japanese Journal
- Adult Diffuse Astrocytoma in the Medulla Oblongata: Molecular Biological Analyses Including H3F3A Mutation of Histone H3.3
- Reactivation of CDX2 in Gastric Cancer as Mark for Gene Silencing Memory
- Reactivation of CDX2 in Gastric Cancer as Mark for Gene Silencing Memory
Related Links
- tumor promoter Cocarcinogen A substance, often lipid-soluble, that has no intrinsic carcinogenic potential, but which, when applied repeatedly, amplifies cancer ... Disclaimer All content on this website, including dictionary ...
- Tennant R. What is a tumor promoter? Environ Health Perspect. 1999 Aug; 107 (8):A390–A391. [PMC free article] [PubMed] Tennant R. What is a tumor promoter? Environ Health Perspect. 1999 Aug; 107 (8):A390–A391. [PMC free ...
Related Pictures
★リンクテーブル★
[★]
- 英
- tumor promoter, carcinogenic promoter
- 関
- プロモーター、発癌補助物質。がん原物質、発がんプロモーター、腫瘍プロモーター、腫瘍イニシエーター
[★]
腫瘍イニシエーター、発癌イニシエーター
- 関
- carcinogen、tumor promoter
[★]
- 英
- tumor promoter
- 関
- 発がんプロモーター、発癌プロモーター
[★]
- 英
- tumor promoter
- 関
- 発癌プロモーター、腫瘍プロモーター
[★]
- 関
- accelerate、acceleration、expedite、facilitate、facilitation、further、hasten、promotion
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