slow axonal transport

遅い輸送

WordNet

1. not moving quickly; taking a comparatively long time; "a slow walker"; "the slow lane of traffic"; "her steps were slow"; "he was slow in reacting to the news"; "slow but steady growth"
2. cause to proceed more slowly; "The illness slowed him down" (同)slow down, slow up
3. become slow or slower; "Production slowed" (同)slow down, slow up, slack, slacken
4. (used of timepieces) indicating a time earlier than the correct time; "the clock is slow"
5. at a slow tempo; "the band played a slow waltz"
6. move something or somebody around; usually over long distances
7. an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
8. move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
9. transport commercially (同)send, ship
10. long nerve fiber that conducts away from the cell body of the neuron (同)axone
11. of or relating to or resembling an axon

PrepTutorEJDIC

1. (速度・動作などが)『遅い』,のろい / 《補語または名詞の後にのみ用いて》(時計などが)『遅れている』 / 『ゆったりした』,あわてない / (人が)理解の遅い,頭の鈍い / (生活・パーティーなどが)『活気のない』,おもしろくない / 遅く,ゆっくり(slowly) / 『遅くなる』,速度を落とす《+『down』(『up』)》 / …‘を'『遅くする』,‘の'速度を落とす《+『名』+『down』(『up』),+『down』(『up』)+『名』》
2. (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機

UpToDate Contents

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English Journal

• Utilization of the bootstrap method for determining confidence intervals of parameters for a model of MAP1B protein transport in axons.

• Kuznetsov IA1, Kuznetsov AV2.
• Journal of theoretical biology.J Theor Biol.2017 Feb 16. pii: S0022-5193(17)30070-X. doi: 10.1016/j.jtbi.2017.02.017. [Epub ahead of print]
• This paper develops a model of axonal transport of MAP1B protein. The problem of determining parameter values for the proposed model utilizing limited available experimental data is addressed. We used a global minimum search algorithm to find parameter values that minimize the discrepancy between mo
• PMID 28216427

• Phosphatidylserine Ameliorates Neurodegenerative Symptoms and Enhances Axonal Transport in a Mouse Model of Familial Dysautonomia.

• Naftelberg S1, Abramovitch Z1, Gluska S2, Yannai S1, Joshi Y2, Donyo M1, Ben-Yaakov K2, Gradus T2, Zonszain J1, Farhy C1, Ashery-Padan R1, Perlson E2, Ast G1.
• PLoS genetics.PLoS Genet.2016 Dec 20;12(12):e1006486. doi: 10.1371/journal.pgen.1006486. eCollection 2016.
• Familial Dysautonomia (FD) is a neurodegenerative disease in which aberrant tissue-specific splicing of IKBKAP exon 20 leads to reduction of IKAP protein levels in neuronal tissues. Here we generated a conditional knockout (CKO) mouse in which exon 20 of IKBKAP is deleted in the nervous system. The
• PMID 27997532

• Microtubule stabilising peptides rescue tau phenotypes in-vivo.

• Quraishe S1, Sealey M1, Cranfield L1, Mudher A1.
• Scientific reports.Sci Rep.2016 Dec 2;6:38224. doi: 10.1038/srep38224.
• The microtubule cytoskeleton is a highly dynamic, filamentous network underpinning cellular structure and function. In Alzheimer's disease, the microtubule cytoskeleton is compromised, leading to neuronal dysfunction and eventually cell death. There are currently no disease-modifying therapies to sl
• PMID 27910888

Japanese Journal

• Where does slow axonal transport go?

• TERADA Sumio
• Neuroscience research : the official journal of the Japan Neuroscience Society 47(4), 367-372, 2003-12-01
• NAID 10016209109

• The Effects of Ginkgo Biloba Extract (GBe) on Axonal Transport, Microvasculature and Morphology of Sciatic Nerve in Streptozotocin-induced Diabetic Rats

• , ,
• Environmental health and preventive medicine 5(2), 53-59, 2000-07
• … To evaluate the protective effects of Ginkgo biloba extract (GBe) which has antioxidant activity against peripheral neuropathy due to diabetes mellitus, slow axonal transport and morphology of sciatic nerve including endoneurial microvessels were examined in 12 rats with diabetes mellitus induced by streptozotocin (STZ, 60mg/kg, b.w., i.p.). …
• NAID 110002694710

• Slow axonal tansport : the subunit transport model

• HIROKAWA N.
• Trends. Cell Biol. 7, 384-388, 1997
• NAID 30009497088

Related Links

• Slow Axonal Transport - Basic Neurochemistry - NCBI Bookshelf

Axonal growth and regeneration are limited by rates of slow axonal transport The rate of axonal growth during development and regeneration of a nerve is roughly equivalent to the rate of SCb in that neuron [3]. This suggests that ...

• Slow Axonal Transport - Encyclopedia of Neuroscience

Slow axonal transport is the movement of cytoskeletal polymers and cytosolic protein complexes along axons at average rates on the order of millimeters per day, ... Accumulation Techniques The oldest and simplest technique for ...

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★リンクテーブル★

リンク元	「遅い輸送」
関連記事	「transport」「slow」「axonal」「slowing」

「遅い輸送」

　　[★]

英

slow axonal transport, slow transport

関

軸索輸送

「transport」

　　[★]

• n.

• 輸送、運搬

• v.

• 輸送する、運搬する、運ぶ

関

bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation

　 　 　 　 　

「slow」

　　[★]

• adj.

• (比較級slower-最上級slowest)緩徐な、遅い、ゆっくりとした、緩慢な

• v.

• 遅くする

関

gradual、gradually、late、slowly、sluggish

　 　 　 　 　 　

「axonal」

　　[★]

• adj.

• 軸索の

関

axon 軸索

　

「slowing」

　　[★]

• n.

• 緩徐化、徐脈化