WordNet

with the wind abaft the beam; "a ship sailing large"
a garment size for a large person
above average in size or number or quantity or magnitude or extent; "a large city"; "set out for the big city"; "a large sum"; "a big (or large) barn"; "a large family"; "big businesses"; "a big expenditure"; "a large number of newspapers"; "a big group of scientists"; "large areas of the world" (同)big
at a distance, wide of something (as of a mark)
fairly large or important in effect; influential; "played a large role in the negotiations"
having broad power and range and scope; "taking the large view"; "a large effect"; "a large sympathy"
the part of the alimentary canal between the stomach and the anus (同)bowel, gut

PrepTutorEJDIC

(同じ種類のものと比較して,形・体積・数量などが)『大きい』,多い,広い / (考えなどが)広範囲な,幅の広い,寛大な / 大きく / 自慢して,誇大に
《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
腸
OLD French古[代]フランス語

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 家族性腺腫性ポリポーシスの臨床症状および診断 clinical manifestations and diagnosis of familial adenomatous polyposis
2. MUTYH関連ポリポーシス mutyh associated polyposis
3. 家族性腺腫性ポリポーシス：患者および家族のスクリーニングおよびマネージメント familial adenomatous polyposis screening and management of patients and families
4. 小腸および大腸の腹部超音波検査 transabdominal ultrasonography of the small and large intestine
5. びまん性大細胞型B細胞性リンパ腫の疫学、臨床症状、病理学的特徴、および診断 epidemiology clinical manifestations pathologic features and diagnosis of diffuse large b cell lymphoma

English Journal

Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

Sur IK, Hallikas O, Vähärautio A, Yan J, Turunen M, Enge M, Taipale M, Karhu A, Aaltonen LA, Taipale J.SourceScience for Life Center, Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
Science (New York, N.Y.).Science.2012 Dec 7;338(6112):1360-3. doi: 10.1126/science.1228606. Epub 2012 Nov 1.
Multiple cancer-associated single-nucleotide polymorphisms (SNPs) have been mapped to conserved sequences within a 500-kilobase region upstream of the MYC oncogene on human chromosome 8q24. These SNPs may affect cancer development through altered regulation of MYC expression, but this hypothesis has
PMID 23118011

Serrated polyps of the large intestine: current understanding of diagnosis, pathogenesis, and clinical management.

Rosty C, Hewett DG, Brown IS, Leggett BA, Whitehall VL.SourceEnvoi Pathology, 1/49 Butterfield Street, Herston, Brisbane, QLD, 4006, Australia, c.rosty@uq.edu.au.
Journal of gastroenterology.J Gastroenterol.2012 Dec 4. [Epub ahead of print]
Approximately 30 % of colorectal carcinomas develop via the serrated neoplasia pathway characterized by widespread DNA methylation and frequent BRAF mutation. Serrated polyps represent a heterogeneous group of polyps which are the precursor lesions to serrated pathway colorectal carcinomas. The his
PMID 23208018

Multiplicity and Molecular Heterogeneity of Colorectal Carcinomas in Individuals With Serrated Polyposis.

Rosty C, Walsh MD, Walters RJ, Clendenning M, Pearson SA, Jenkins MA, Win AK, Hopper JL, Sweet K, Frankel WL, Aronson M, Gallinger S, Goldblatt J, Tucker K, Greening S, Gattas MR, Woodall S, Arnold J, Walker NI, Parry S, Young JP, Buchanan DD.Source*Cancer and Population Studies Group, Queensland Institute of Medical Research, Bancroft Centre †School of Medicine, University of Queensland ‡Envoi Pathology ##Queensland Clinical Genetics Service, Royal Childrens' Hospital, Herston, Qld §Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, School of Population Health, The University of Melbourne, Carlton, Vic., Australia ‡‡School of Paediatrics and Child Health, University of Western Australia, Nedlands §§Genetic Services of Western Australia, Subiaco, WA ∥∥Hereditary Cancer Clinic, Prince of Wales Hospital, Randwick ¶¶Illawarra Cancer Centre, Wollongong Hospital, Wollongong, NSW, Australia ∥Department of Internal Medicine, Division of Human Genetics, Comprehensive Cancer Center ¶Department of Pathology, Ohio State University, Columbus, OH #Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital **Cancer Care Ontario ††Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada ***New Zealand Familial Gastrointestinal Cancer Registry, Auckland City Hospital †††Department of Gastroenterology, Middlemore Hospital, Auckland, New Zealand.
The American journal of surgical pathology.Am J Surg Pathol.2012 Dec 1. [Epub ahead of print]
Serrated polyposis (SP) is a clinically defined syndrome characterized by the occurrence of multiple serrated polyps in the large intestine. Individuals with SP and their relatives are at increased risk of colorectal carcinoma (CRC). We aimed to determine the pathologic and molecular profiles of CRC
PMID 23211288