シーハン症候群
WordNet
- of or relating to the pituitary gland; "pituitary hormone"
- the master gland of the endocrine system; located at the base of the brain (同)pituitary_gland, pituitary body, hypophysis
- the localized death of living cells (as from infection or the interruption of blood supply) (同)mortification, gangrene, sphacelus
PrepTutorEJDIC
- 脳下垂体の(から得られた) / =pituitary gland
- 壊疽(えそ)
UpToDate Contents
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English Journal
- Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing.
- Mekli K1, Nazroo JY, Marshall AD, Kumari M, Pendleton N.
- Aging clinical and experimental research.Aging Clin Exp Res.2015 Aug 7. [Epub ahead of print]
- BACKGROUND: Frailty is a state of increased vulnerability to poor resolution of homeostasis after a stressor event, which increases the risk of adverse outcomes including falls, disability and death. The underlying pathophysiological pathways of frailty are not known but the hypothalamic-pituitary-a
- PMID 26248682
- Autoimmune lymphocytic hypophysitis in association with autoimmune eye disease and sequential treatment with infliximab and rituximab.
- Xu C1, Ricciuti A, Caturegli P, Keene CD, Kargi AY.
- Pituitary.Pituitary.2015 Aug;18(4):441-7. doi: 10.1007/s11102-014-0592-7.
- INTRODUCTION: Autoimmune lymphocytic hypophysitis associates predominantly with other autoimmune endocrinopathies and is most commonly treated with glucocorticoids and/or decompressive pituitary surgery. Here we report a new association and treatment modality for lymphocytic hypophysitis.METHODS: A
- PMID 25224140
- Adrenal gland volume, intra-abdominal and pericardial adipose tissue in major depressive disorder.
- Kahl KG1, Schweiger U2, Pars K3, Kunikowska A3, Deuschle M4, Gutberlet M5, Lichtinghagen R6, Bleich S3, Hüper K5, Hartung D5.
- Psychoneuroendocrinology.Psychoneuroendocrinology.2015 Aug;58:1-8. doi: 10.1016/j.psyneuen.2015.04.008. Epub 2015 Apr 20.
- Major depressive disorder (MDD) is associated with an increased risk for the development of cardio-metabolic diseases. Increased intra-abdominal (IAT) and pericardial adipose tissue (PAT) have been found in depression, and are discussed as potential mediating factors. IAT and PAT are thought to be t
- PMID 25935636
Japanese Journal
- Reversible Hypopituitarism with Pituitary Tuberculoma
- General Anesthetics Inhibit LPS-Induced IL-1β Expression in Glial Cells.
- Long-Term Follow-Up of Growth Hormone-Producing Pituitary Carcinoma With Multiple Spinal Metastases Following Multiple Surgeries: Case Report
- Neurologia medico-chirurgica = 神経外科 53(10), 707-711, 2013-10-15
- NAID 10031191642
Related Links
- Sheehan syndrome, also known as Simmonds' syndrome or postpartum hypopituitarism or postpartum pituitary necrosis, is hypopituitarism (decreased functioning of the pituitary gland), caused by necrosis due to blood loss and hypovolemic ...
- 1 Feb 2012 ... Postpartum pituitary necrosis symptoms, causes, diagnosis, and treatment information for Postpartum pituitary necrosis (Sheehan Syndrome) with alternative diagnoses, full-text book chapters, misdiagnosis, research ...
★リンクテーブル★
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- 英
- Sheehan syndrome, Sheehan's syndrome
- 同
- 分娩後下垂体機能低下症 postpartum hypopituitarism
- 下垂体梗塞 pituitary necrosis
- 関
- 下垂体機能低下症、ホルモン
概念
- 分娩時の大出血またはショックにより、下垂体血管に攣縮および二次的血栓が生じて下垂体の梗塞、壊死が起こり、これにより下垂体前葉機能低下症を呈した病態。
症状
- (軽症)乳汁分泌不全、腋毛・恥毛の脱落、無月経 (NGY.157)
- (重症例)甲状腺・副腎機能の障害による無気力・易疲労感 (NGY.157)
- 低血糖(GH低値による)
- G9M.34
- 第2度無月経、性器・乳腺萎縮、やせ、乳汁分泌低下、恥毛・腋毛の脱落、無力感、低血糖症状
| ACTH↓
|
易疲労感、低血糖、低ナトリウム血症、低血圧、恥毛・腋毛の脱落
|
| PRL↓
|
乳汁分泌低下
|
| TSH↓
|
耐寒性の低下、不活発、便秘、皮膚の乾燥
|
| GH↓
|
筋力低下、体脂肪増加
|
| FSH・LH↓
|
エストロゲン↓
|
第2度無月経、性欲低下、乳房・内外性器の萎縮、骨粗鬆症
|
| プロゲステロン↓
|
基礎体温：低温1相
|
検査
MRI
- G9M.34
治療
鑑別疾患
症例
- 35歳女性。無月経を主訴に来院した。1回経産婦で、分娩時弛緩出血のためショックとなり緊急輸血を施行した。妊娠前の月経周期は28日型の整手有り、分娩後5年が経過したが月経の発来はなかった。軽度のるいそうを認める。
- 48歳女性。易疲労感の増悪を訴え来院。30歳の時、第2子分娩後、大量出血し、その後月経が消失していた。数年前より、易疲労感、耐寒性の低下を自覚し、近医を受診。甲状腺機能低下症と診断され、甲状腺ホルモン薬が処方され、服用していたが改善せず、むしろ増悪傾向にあった。
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- 関
- hypophyses、hypophysis、pituitary gland