胎児循環残存症候群
WordNet
- (library science) the count of books that are loaned by a library over a specified period
- movement through a circuit; especially the movement of blood through the heart and blood vessels
- number of copies of a newspaper or magazine that are sold; "by increasing its circulation the newspaper hoped to increase its advertising"
- the spread or transmission of something (as news or money) to a wider group or area
- free movement or passage (as of cytoplasm within a cell or sap through a plant); "ocean circulation is an important part of global climate"; "a fan aids air circulation"
- the dissemination of copies of periodicals (as newspapers or magazines)
- never-ceasing; "the relentless beat of the drums" (同)relentless, unrelenting
- retained; not shed; "persistent leaves remain attached past maturity"; "the persistent gills of fishes" (同)lasting
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
- of or relating to a fetus; "fetal development" (同)foetal
PrepTutorEJDIC
- 〈U〉『血液の循環』,血行 / 〈U〉(貨幣の)流通;(情報・うわさなどの)流布伝達;(新聞・雑誌など,印刷物の)配布 / 〈C〉(新聞・雑誌などの)発行部数
- (反対・困難にもくじけず)『あくまでもやり抜く』,ねばり強い,執ような / いつまでも続く,持続する(lasting)
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/30 11:17:56」(JST)
[Wiki en表示]
| Persistent foetal circulation |
| Classification and external resources |
| ICD-10 |
P29.3 |
| ICD-9 |
747.83 |
| DiseasesDB |
29889 |
| eMedicine |
ped/2530 |
| MeSH |
D010547 |
Persistent fetal circulation is a condition caused by a failure in the systemic circulation and pulmonary circulation to convert from the antenatal circulation pattern to the "normal" pattern.
In a fetus, there is high pulmonary vascular resistance and low pulmonary blood flow as the fetus does not use the lungs for oxygen transfer. Once the baby is born, the lungs are needed for oxygen transfer and need high blood flow which is encouraged by low pulmonary vascular resistance.
It can be associated with pulmonary hypertension.[1] Because of this, the condition is also known as "persistent pulmonary hypertension of the newborn".[2]
Contents
- 1 Epidemiology
- 2 Types
- 2.1 Normal vascular anatomy with functional vasoconstriction
- 2.2 Decreased diameter of pulmonary vessels with hypertrophy of vessel walls
- 2.3 Decreased size of pulmonary vascular bed
- 2.4 Functional obstruction of pulmonary blood flow
- 3 Treatment
- 4 References
- 5 External links
Epidemiology[edit]
It occurs in 1-2 infants per 1000 live births[3]
Types[edit]
Normal vascular anatomy with functional vasoconstriction[edit]
This has a good prognosis, as it is reversible. Causes include hypoxia, meconium aspiration, and respiratory distress syndrome.
Decreased diameter of pulmonary vessels with hypertrophy of vessel walls[edit]
This has a poor prognosis, as it is a fixed abnormality. Causes include post-term pregnancy, placental insufficiency, and NSAID use by the mother.
Decreased size of pulmonary vascular bed[edit]
This has a poor prognosis, as it is a fixed abnormality. It is caused by space occupying lesions such as pleural effusions and diaphragmatic hernias.
Functional obstruction of pulmonary blood flow[edit]
This has a good prognosis if it is reversible. Causes include polycythemia and hyperfibrinogenemia. [4]
Treatment[edit]
Treatment aims to increase the amount of oxygen in the blood and reverse any causes of hypoxia.
- oxygen therapy
- mechanical ventilation
- NO Inhalation
- Prostaglandins (intravenous)
References[edit]
- ^ "Medcyclopaedia - Persistent fetal circulation". Archived from the original on 2012-02-05.
- ^ "PERSISTENT PULMONARY HYPERTENSION OF THE NEWBORN".
- ^ 1. Chambers CD, Hernandez-Diaz S, Van Marter LJ, et al. Selective serotonin-reuptake inhibitors and risk of persistent pulmonary hypertension of the newborn. N. Engl. J. Med. 2006;354(6):579-587. Available at: http://www.ncbi.nlm.nih.gov/pubmed/16467545
- ^ Graves E, Redmond C, Arensman R. Persistent pulmonary hypertension in the neonate. Chest. 1988;93(3):638-641. Available at: http://chestjournal.chestpubs.org/content/93/3/638.long
External links[edit]
- http://www.kumc.edu/instruction/medicine/pedcard/cardiology/pedcardio/pfcdiagram.gif
- Dunn PM (March 1994). "Professor Charles D Meigs (1792-1869) of Philadelphia and persistent fetal circulation". Arch. Dis. Child. Fetal Neonatal Ed. 70 (2): F155–6. doi:10.1136/fn.70.2.F155. PMC 1061019. PMID 8154909.
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Certain conditions originating in the perinatal period / fetal disease (P, 760–779)
|
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Maternal factors and
complications of pregnancy,
labour and delivery |
placenta: Placenta praevia · Placental insufficiency · Twin-to-twin transfusion syndrome
chorion/amnion: Chorioamnionitis
umbilical cord: Umbilical cord prolapse · Nuchal cord · Single umbilical artery
|
|
Length of gestation
and fetal growth |
Small for gestational age/Large for gestational age · Preterm birth/Postmature birth · Intrauterine growth restriction
|
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| Birth trauma |
scalp (Cephalhematoma, Chignon, Caput succedaneum, Subgaleal hemorrhage) · Brachial plexus lesion (Erb's palsy, Klumpke paralysis)
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| By system |
|
Respiratory
|
Intrauterine hypoxia · Infant respiratory distress syndrome · Transient tachypnea of the newborn · Meconium aspiration syndrome · pleural disease (Pneumothorax, Pneumomediastinum) · Wilson-Mikity syndrome · Bronchopulmonary dysplasia
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|
Cardiovascular
|
Pneumopericardium · Persistent fetal circulation
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|
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Haemorrhagic and
hematologic disease
|
Vitamin K deficiency (Haemorrhagic disease of the newborn)
HDN (ABO • Anti-Kell • Rh c • Rh D • Rh E) · Hydrops fetalis · Hyperbilirubinemia (Kernicterus, Neonatal jaundice)
Velamentous cord insertion
Intraventricular hemorrhage (Germinal matrix hemorrhage)
Anemia of prematurity
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Digestive
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Ileus · Necrotizing enterocolitis · Meconium peritonitis
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Integument and
temperature regulation
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Erythema toxicum · Sclerema neonatorum
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Nervous system
|
Periventricular leukomalacia
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Musculoskeletal
|
Gray baby syndrome · muscle tone (Congenital hypertonia, Congenital hypotonia)
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| Infectious |
Vertically transmitted infection (Congenital rubella syndrome, Neonatal herpes simplex) · Omphalitis · Neonatal sepsis (Group B streptococcal infection) · Neonatal conjunctivitis
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| Other |
Perinatal mortality (Stillbirth, Infant mortality) · Neonatal withdrawal
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Congenital vascular defects / Vascular malformation (Q25–Q28, 747)
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Great arteries/
other arteries |
|
Aorta
|
- Patent ductus arteriosus
- Coarctation of the aorta
- Interrupted aortic arch
- Double aortic arch
- Right-sided aortic arch
- Overriding aorta
- Aneurysm of sinus of Valsalva
- Vascular ring
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Pulmonary artery
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- Pulmonary atresia
- Stenosis of pulmonary artery
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Subclavian artery
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- Aberrant subclavian artery
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Umbilical artery
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| Great veins |
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Superior/inferior vena cava
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- Congenital stenosis of vena cava
- Persistent left superior vena cava
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Pulmonary vein
|
- Anomalous pulmonary venous connection (Total, Partial)
- Scimitar syndrome
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| Arteriovenous malformation |
- Cerebral arteriovenous malformation
|
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anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot
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noco/syva/cong/lyvd/tumr, sysi/epon, injr
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proc, drug (C2s+n/3/4/5/7/8/9)
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UpToDate Contents
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English Journal
- The management of neonatal pulmonary hypertension.
- Dhillon R.SourceDepartment of Cardiac Services, Birmingham Children's Hospital, UK. rami.dhillon@bch.nhs.uk
- Archives of disease in childhood. Fetal and neonatal edition.Arch Dis Child Fetal Neonatal Ed.2012 May;97(3):F223-8. Epub 2011 Jan 30.
- Most neonates with clinically significant pulmonary hypertension (PH) will have either persistent PH of the newborn (PPHN) or bronchopulmonary dysplasia. Cyanotic congenital heart disease must be actively ruled out as part of the differential diagnosis of PPHN. The maintenance of ductal patency with
- PMID 21278430
- Neonates presenting with temperature symptoms: Role in the diagnosis of early onset sepsis.
- Hofer N, Müller W, Resch B.SourceResearch Unit for Neonatal Infectious Diseases and Epidemiology, Division of Neonatology, Department of Paediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.
- Pediatrics international : official journal of the Japan Pediatric Society.Pediatr Int.2012 Feb 2. doi: 10.1111/j.1442-200X.2012.03570.x. [Epub ahead of print]
- Background: In this study, we aimed to evaluate the role of fever, hypothermia, and temperature instability in term and preterm newborns during the first 3 days of life and to identify risk factors for early onset sepsis (EOS) among newborns presenting with these temperature symptoms. Methods:
- PMID 22299645
Japanese Journal
- 轟 美詠,李 容桂,根岸 宏邦,野間 大路,西野 昌光,家永 徹也,前田 貢作,山本 哲郎
- 日本新生児学会雑誌 31(3), 463-468, 1995-09-30
- NAID 10005199905
- 膜型人工肺(ECMO)施行例の神経学的評価と短期予後
- 轟 美詠,河合 伸二,李 容桂,根岸 宏邦,伊東 恭子,西野 昌光,家永 徹也,前田 貢作,山本 哲郎
- 日本新生児学会雑誌 31(2), 247-253, 1995-06-30
- NAID 10005485381
Related Links
- Persistent Fetal Circulation Syndrome information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues. ... Introduction: Persistent Fetal Circulation Syndrome Description of Persistent ...
- 1: Persistent Fetal Circulation Syndrome A syndrome of persistent PULMONARY HYPERTENSION in the newborn infant (INFANT, NEWBORN) without demonstrable HEART DISEASES. This neonatal condition can be caused by ...
★リンクテーブル★
[★]
- 英
- persistent pulmonary hypertension of newborn, persistent pulmonary hypertension of the newborn persistent pulmonary hypertension in the neonate PPHN
- 同
- 胎児循環残存症候群 胎児循環遺残症 persistent fetal circulation syndrome PFCS、胎児循環残存 persistent fetal circulation PFC
- 新生児遷延性肺高血圧、新生児持続性肺高血圧症
[show details]
概念
- 出生後、肺動脈拡張不全に基づく肺高血圧、および動脈管と卵円孔を介する右左シャントによりチアノーゼを呈する疾患。(SPE.107)
- 肺動脈拡張不全の原因として低酸素血症やアシドーシスがある。
- 以前は胎児循環遺残症と呼ばれていたが使われなくなった。(SPE.107)
病因
- 横隔膜ヘルニア、新生児仮死、胎便吸引症候群、呼吸窮迫症候群、肺低形成
[★]
- 関
- continuous、continuously、insurmountable、long-lasting、permanent、permanently、persistence、persistently、persisting、prolonged、repository、sustained、tonic、tonically
[★]
- 胎生期の、胎性の、(人間)胎児の、胎児性の、(動物)胎仔の、胎仔型の
- 関
- embryo、embryonal、embryonic、embryonic day、embryonic form、embryonic stage、fetal stage、feto、fetus、foetal、foetus
[★]
- 関
- blood circulation、circulate、circulatory、hematogenic
[★]