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1. 感染症を繰り返す小児に対するアプローチapproach to the child with recurrent infections [show details]
… (SCID) is considered a pediatric emergency, and special precautions should be taken if this diagnosis is suspected. The majority of children who present with recurrent infections, especially localized …
2. Infectious causes of peripheral eosinophiliainfectious causes of peripheral eosinophilia [show details]
… associated with chronic infection. Hymenolepis nana – Hymenolepis nana is a tapeworm infection found in tropical and subtropical countries worldwide. It occurs most commonly in children, with fecal-oral transmission …
3. 小児の黄色ブドウ球菌感染症：侵襲性感染症の治療の概要staphylococcus aureus in children overview of treatment of invasive infections [show details]
… expert in pediatric infectious diseases is suggested in the management of children with VRSA infections. Although we monitor vancomycin levels in children with renal dysfunction and children with serious …
4. 最近の上気道感染を有する小児に対する麻酔anesthesia for the child with a recent upper respiratory infection [show details]
…Upper respiratory infection (URI) is the most frequent human illness and the most common infection in childhood; infants and preschoolers have six to eight URIs per year . Thus, children commonly present …
5. 小児の後天性サイトメガロウイルス感染症の概要overview of cytomegalovirus infections in children [show details]
…demonstration of infection in blood and an end organ. Treatment of acquired CMV infections in infants and children depends on the clinical circumstances : Preterm infants with early postnatal infection – For …

English Journal

Complete clinical remission of invasive Candida infection with CARD9 deficiency after G-CSF treatment.

Du B, Shen N, Hu J, Tao Y, Mo X, Cao Q.
Comparative immunology, microbiology and infectious diseases. 2020 Jun;70()101417.
Caspase-associated recruitment domain-containing protein 9 (CARD9) deficiency is an autosomal-recessive primary immunodeficiency characterized by susceptibility to recurrent Candida infections, and its diagnosis and treatment is challenging. The present study aims to investigate the genetic characte
PMID 32113042

Obese Adolescents With PCOS Have Altered Biodiversity and Relative Abundance in Gastrointestinal Microbiota.

Jobira B, Frank DN, Pyle L, Silveira LJ, Kelsey MM, Garcia-Reyes Y, Robertson CE, Ir D, Nadeau KJ, Cree-Green M.
The Journal of clinical endocrinology and metabolism. 2020 Jun;105(6).
Alterations in gut microbiota relate to the metabolic syndrome, but have not been examined in at-risk obese youth with polycystic ovary syndrome (PCOS). Compare the composition and diversity of the gut microbiota and associations with metabolic and hormonal measures between 2 groups of female adoles
PMID 31970418

Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome.

Béziat V, Tavernier SJ, Chen YH, Ma CS, Materna M, Laurence A, Staal J, Aschenbrenner D, Roels L, Worley L, Claes K, Gartner L, Kohn LA, De Bruyne M, Schmitz-Abe K, Charbonnier LM, Keles S, Nammour J, Vladikine N, Maglorius Renkilaraj MRL, Seeleuthner Y, Migaud M, Rosain J, Jeljeli M, Boisson B, Van Braeckel E, Rosenfeld JA, Dai H, Burrage LC, Murdock DR, Lambrecht BN, Avettand-Fenoel V, Vogel TP, , Esther CR, Haskologlu S, Dogu F, Ciznar P, Boutboul D, Ouachée-Chardin M, Amourette J, Lebras MN, Gauvain C, Tcherakian C, Ikinciogullari A, Beyaert R, Abel L, Milner JD, Grimbacher B, Couderc LJ, Butte MJ, Freeman AF, Catherinot É, Fieschi C, Chatila TA, Tangye SG, Uhlig HH, Haerynck F, Casanova JL, Puel A.
The Journal of experimental medicine. 2020 Jun;217(6).
Autosomal dominant hyper-IgE syndrome (AD-HIES) is typically caused by dominant-negative (DN) STAT3 mutations. Patients suffer from cold staphylococcal lesions and mucocutaneous candidiasis, severe allergy, and skeletal abnormalities. We report 12 patients from 8 unrelated kindreds with AD-HIES due
PMID 32207811

Japanese Journal

アフリカでの脳卒中低減を目指した医科─歯科国際連携の試み

殿村修一,井上学,角田良介,野村良太,仲野和彦,猪原匡史
脳卒中 42(2), 107-108, 2020
NAID 130007815617

新生児期にエンテロウイルスによる急性心筋炎を発症した1例

山形知慧,藤本嗣人,岡明,進藤考洋,白神一博,朝海廣子,平田陽一郎,犬塚亮,金子明依,高梨さやか,水口雅
日本小児循環器学会雑誌 35(4), 284-289, 2019
<p>新生児心筋炎は致死率が50％以上と高く，エンテロウイルスは代表的な原因ウイルスとして知られている．今回我々はエンテロウイルスによる新生児期の急性心筋炎の症例を経験したので報告する．患者は40週1日，2,637 gで出生した．日齢2に発熱が出現し，日齢7に過剰心音を認め，心エコー検査では左室駆出率の低下を認めトロポニンTも陽性であったことから急性心筋炎の診断でカテコラミンによる治療 …
NAID 130007797789

Determinants of Vaccination Coverage for the Second Dose of Measles-Rubella Vaccine in Tokyo, Japan

Sugishita Yoshiyuki,Kurita Junko,Akagi Takanobu,Sugawara Tamie,Ohkusa Yasushi
The Tohoku Journal of Experimental Medicine 249(4), 265-273, 2019
… the ratio of the number of pediatric medical facilities to the number of preschool and elementary school children; …
NAID 130007762570

「小児感染症」

　　[★]

英: pediatric infectious disease
関: 感染症

夏に流行する感染症

病名	手足口病	ヘルパンギーナ	咽頭結膜熱
通称			プール熱
症状	口の中、手のひら、足の平などに紅斑や水疱が出現する。高熱は出ないことが多い。	突然の高熱で発症し、口の中の奥に水疱や潰瘍ができる	発熱、咽頭炎、結膜炎などの症状がでる
病原体	エンテロウイルス属(コクサッキーウイルスA群、エンテロウイルス71型など)		アデノウイルス
感染経路	飛沫感染、接触感染	飛沫感染、接触感染	飛沫感染、接触感染
治療	対症療法	対症療法	対症療法