WordNet
- a yellow phospholipid essential for the metabolism of fats; found in egg yolk and in many plant and animal cells; used commercially as an emulsifier
PrepTutorEJDIC
- 〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
- レシチン(神経細胞や卵黄などに含まれるリン脂質)
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/01/22 14:37:09」(JST)
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- 1. 棘状細胞（棘状赤血球および有棘赤血球）と標的細胞の原因 causes of spiculated cells echinocytes and acanthocytes and target cells
- 2. リポ蛋白の分類、代謝、およびアテローム性動脈硬化症における役割 lipoprotein classification metabolism and role in atherosclerosis
- 3. HDLコレステロール：異常値の臨床的側面 hdl cholesterol clinical aspects of abnormal values
- 4. 水溶性ビタミンの概要 overview of water soluble vitamins
- 5. 胎児肺の成熟度評価 assessment of fetal lung maturity
English Journal
- Severe high-density lipoprotein deficiency associated with autoantibodies against lecithin:cholesterol acyltransferase in non-hodgkin lymphoma.
- Simonelli S, Gianazza E, Mombelli G, Bondioli A, Ferraro G, Penco S, Sirtori CR, Franceschini G, Calabresi L.SourceCenter E. Grossi Paoletti, Department of Pharmacological Sciences, Università degli Studi di Milano, via Balzaretti 9, 20133 Milano, Italy. laura.calabresi@unimi.it.
- Archives of internal medicine.Arch Intern Med.2012 Jan 23;172(2):179-81.
- An antibody against the lecithin:cholesterol acyltransferase (LCAT) enzyme, which negates cholesterol esterification in plasma, causing severe high-density lipoprotein deficiency (HD), was identified in a woman with a large-cell non-Hodgkin lymphoma. Successful treatment of the lymphoma resulted in
- PMID 22271127
- The role of lecithin:cholesterol acyltransferase in the modulation of cardiometabolic risks - A clinical update and emerging insights from animal models.
- Ng DS.AbstractLecithin cholesterol acyltransferase (LCAT) is the key enzyme in mediating the esterification of cholesterol on circulating lipoproteins. It has long been suggested that LCAT plays a crucial role in reverse cholesterol transport, a process depicting the removal of cellular cholesterol through efflux to high density lipoproteins (HDL) and its delivery to the liver for eventual excretion from the body. Although loss-of-function LCAT mutations invariably result in profound HDL deficiency, the role of LCAT in atherogenesis continues to be clouded with controversy. Increasing number of large scale, population-based studies failed to detect an elevated cardiac risk with reduced blood levels of LCAT, suggesting that reduced LCAT activity may not be a risk factor nor a therapeutic target. More recent studies in human LCAT gene mutation carriers tend to suggest that atherogenicity in LCAT deficiency may be dependent on the nature of the mutations, providing plausible explanations for the otherwise contradictory findings. Genetic models of LCAT excess or deficiency yielded mixed findings. Despite it known profound effects on HDL and triglyceride metabolism, the role of LCAT in metabolic disorders, including obesity and diabetes, has not received much attention. Recent studies in LCAT deficient mouse models suggest that absence of LCAT may protect against insulin resistance, diabetes and obesity. Coordinated modulation of a number of anti-obesity and insulin sensitizing pathways has been implicated. Further studies to explore the role of LCAT in the modulation of cardiometabolic disorders and the underlying mechanisms are warranted.
- Biochimica et biophysica acta.Biochim Biophys Acta.2012 Jan 12. [Epub ahead of print]
- Lecithin cholesterol acyltransferase (LCAT) is the key enzyme in mediating the esterification of cholesterol on circulating lipoproteins. It has long been suggested that LCAT plays a crucial role in reverse cholesterol transport, a process depicting the removal of cellular cholesterol through efflux
- PMID 22326749
- Chameleon-like appearance of immunotactoid keratopathy.
- Lisch W, Saikia P, Pitz S, Pleyer U, Lisch C, Jaeger M, Rohrbach JM.Sourceprof.dr.lisch@augenklinik-hanau.de
- Cornea.Cornea.2012 Jan;31(1):55-8.
- PURPOSE: To demonstrate 5 different patterns of immunotactoid keratopathy (ITK) in monoclonal gammopathy of undetermined significance (MGUS) that can mimic hereditary and degenerative disorders. First follow-up of 1 female patient was performed.METHODS: Colored slit-lamp photodocumentation of 6 MGUS
- PMID 21941171
Japanese Journal
- Corticosteroid treatment of kidney disease in a patient with familial lecithin-cholesterol acyltransferase deficiency
- MIARKA Przemyslaw,IDZIOR-WALUS Barbara,KUZNIEWSKI Marek,WALUS-MIARKA Malgorzata,KLUPA Tomasz,SULOWICZ Wladyslaw
- Clinical and experimental nephrology 15(3), 424-429, 2011-06-01
- NAID 10029005945
- 眼科図譜(358)LCAT(lecithin-cholesterol acyltransferase)欠損症に伴った角膜混濁の1例
- 石崎 こずえ,竹澤 美貴子,牧野 伸二 [他]
- 臨床眼科 65(1), 12-15, 2011-01
- NAID 40018700067
- 原発性低脂血症の病型分類と病因・臨床徴候・管理法 原発性低LDLコレステロール血症 家族性LCAT欠損症 (脂質代謝異常--高脂血症・低脂血症) -- (脂質代謝異常の臨床 低脂血症)
- 高橋 貞夫
- 日本臨床 65(-) (919), 614-617, 2007-07
- NAID 40015559465
Related Links
- Lecithin-Cholesterol Acyltransferase Deficiency. The two familial forms of lecithin-cholesterol acyltransferase (LCAT) deficiency are termed familial LCAT deficiency (complete LCAT deficiency) and fish eye disease (partial ... ...
- Information about Lecithin acyltransferase deficiency in Free online English dictionary. What is Lecithin acyltransferase deficiency? Meaning of Lecithin acyltransferase deficiency medical term. What does Lecithin acyltransferase ...
Related Pictures
★リンクテーブル★
| リンク元 | 「レシチンアシルトランスフェラーゼ欠損症」 |
| 関連記事 | 「deficiency」「lecithin acyltransferase」「acyltransferase」 |
「レシチンアシルトランスフェラーゼ欠損症」
「deficiency」
- n.
- 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
- 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの
- 関
- absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve