耐糖能障害 IGT、glucose intolerance
WordNet
- the act of tolerating something
- the power or capacity of an organism to tolerate unfavorable environmental conditions
- willingness to recognize and respect the beliefs or practices of others
- make worse or less effective; "His vision was impaired"
- diminished in strength, quality, or utility; "impaired eyesight"
- a monosaccharide sugar that has several forms; an important source of physiological energy
PrepTutorEJDIC
- (自分と異なる他人の意見・行動などを許す)寛大,寛容・我慢（がまん）,忍耐力 / (薬品・毒物などに対する)耐性,抗毒性 / 公差,許容誤差
- 〈健康・視力など〉‘を'損なう,〈判断力など〉‘を'弱める
- ブドウ糖
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2017/03/19 15:33:37」(JST)
[Wiki en表示]
| Impaired glucose tolerance |
| Classification and external resources |
| ICD-10 |
R73.0 |
| ICD-9-CM |
790.21 |
| MeSH |
D018149 |
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[edit on Wikidata]
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Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with insulin resistance and increased risk of cardiovascular pathology. IGT may precede type 2 diabetes mellitus by many years. IGT is also a risk factor for mortality.[1]
Contents
- 1 Criteria
- 2 Treatment
- 3 See also
- 4 References
- 5 Further reading
Criteria
According to the criteria of the World Health Organization and the American Diabetes Association, impaired glucose tolerance is defined as:[2][3][4]
- two-hour glucose levels of 140 to 199 mg per dL (7.8 to 11.0 mmol/l) on the 75-g oral glucose tolerance test. A patient is said to be under the condition of IGT when he/she has an intermediately raised glucose level after 2 hours, but less than the level that would qualify for type 2 diabetes mellitus. The fasting glucose may be either normal or mildly elevated.
From 10 to 15 percent of adults in the United States have impaired glucose tolerance or impaired fasting glucose.[5]
Treatment
Main article: Prevention of diabetes mellitus type 2
The risk of progression to diabetes and development of cardiovascular disease is greater than for impaired fasting glucose.[6]
Although some drugs can delay the onset of diabetes, lifestyle modifications play a greater role in the prevention of diabetes.[5][7] Patients identified as having an IGT may be able to prevent diabetes through a combination of increased exercise and reduction of body weight.[5] "Drug therapy can be considered when aggressive lifestyle interventions are unsuccessful."[5]
See also
- Glucose tolerance test
- Impaired fasting glucose
References
- ^ Barr EL, Zimmet PZ, Welborn TA, et al. (2007). "Risk of cardiovascular and all-cause mortality in individuals with diabetes mellitus, impaired fasting glucose, and impaired glucose tolerance: the Australian Diabetes, Obesity, and Lifestyle Study (AusDiab)". Circulation. 116 (2): 151–7. doi:10.1161/CIRCULATIONAHA.106.685628. PMID 17576864.
- ^ .World Health Organization. "Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO Consultation. Part 1. Diagnosis and classification of diabetes mellitus". Retrieved 2007-05-29.
- ^ American Diabetes, Association (2005). "Diagnosis and classification of diabetes mellitus". Diabetes Care. 28 Suppl 1: S37–42. doi:10.2337/diacare.28.suppl_1.s37. PMID 15618111.
- ^ http://www.diabetes.co.uk/impaired-glucose-tolerance.html
- ^ a b c d Shobha S. Rao; Phillip Disraeli; Tamara McGregor (15 April 2004). "Impaired Glucose Tolerance and Impaired Fasting Glucose". American Family Physician. 69 (8): 1961.
- ^ Oxford Handbook of Clinical Medicine, 7th Ed., Longmore, Wilkinson, Turmezei and Cheung. Oxford University Press 2007.
- ^ Raina Elley C, Kenealy T (December 2008). "Lifestyle interventions reduced the long-term risk of diabetes in adults with impaired glucose tolerance". Evid Based Med. 13 (6): 173. doi:10.1136/ebm.13.6.173. PMID 19043031.
Further reading
- Melanie J Davies; I Peter Gray (3 February 1996). "Impaired glucose tolerance". British Medical Journal. 312 (7026): 264–265. doi:10.1136/bmj.312.7026.264. PMC 2349870. PMID 8611769. - Editorial review
- Nathan, DM; Davidson, MB; DeFronzo, RA; Heine, RJ; Henry, RR; Pratley, R; Zinman, B; American Diabetes, Association (March 2007). "Impaired fasting glucose and impaired glucose tolerance: implications for care.". Diabetes Care. 30 (3): 753–9. doi:10.2337/dc07-9920. PMID 17327355.
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Abnormal clinical and laboratory findings for blood tests (R70–R79, 790)
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| Red blood cells |
| Size |
- Anisocytosis
- Macrocyte
- Microcyte
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| Shape |
- Poikilocytosis
- membrane abnormalities:
- Acanthocyte
- Codocyte
- Ovalocyte
- Spherocyte
- Dacrocyte
- Echinocyte
- Schistocyte
- Degmacyte
- Drepanocyte
- Stomatocyte
- Knizocyte
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| Hemoglobinization |
|
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| Inclusion bodies |
- Developmental
- Howell–Jolly body
- Basophilic stippling
- Pappenheimer bodies
- Cabot rings
- Hemoglobin precipitation
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| Other |
- Rouleaux
- Reticulocyte
- Elevated ESR
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| Lymphocytes |
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| Small molecules |
| Blood sugar |
- Hypoglycemia
- Hyperglycemia
- Prediabetes
- Impaired fasting glucose
- Impaired glucose tolerance
- Oxyhyperglycemia
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| Nitrogenous |
- Azotemia
- Hyperuricemia
- Hypouricemia
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|
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| Proteins |
| LFT |
- Elevated transaminases
- Elevated ALP
- Hypoproteinemia
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| Other |
- Elevated cardiac markers
- Elevated alpha-fetoprotein
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| Minerals |
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| Pathogens/sepsis |
- Bacteremia
- Viremia
- Fungemia
- Parasitemia
- Algaemia
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Diabetes (E10–E14, 250)
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| Types |
- Type 1
- Type 2
- LADA
- Gestational diabetes
- Prediabetes
- Impaired fasting glucose
- Impaired glucose tolerance
- Insulin resistance
- KPD
- MODY
- Neonatal
- Type 3c (Pancreatogenic)
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| Blood tests |
- Blood sugar
- Glycosylated hemoglobin
- Glucose tolerance test
- Postprandial glucose test
- Fructosamine
- Glucose test
- C-peptide
- Noninvasive glucose monitor
- Insulin tolerance test
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| Management |
- Diabetic diet
- Anti-diabetic drugs
- Insulin therapy
- intensive
- conventional
- pulsatile
- Cure
- Embryonic stem cells
- Artificial pancreas
- Other
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| Complications |
- Diabetic comas
- Hypoglycemia
- Ketoacidosis
- Hyperosmolar hyperglycemic state
- Diabetic foot
- ulcer
- Neuropathic arthropathy
- Organs in diabetes
- Blood vessels
- Muscle
- Kidney
- Nerves
- Retina
- Heart
- Diabetic skin disease
- Diabetic dermopathy
- Diabetic bulla
- Diabetic cheiroarthropathy
- Neuropathic ulcer
- Hyperglycemia
- Hypoglycemia
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| Other |
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UpToDate Contents
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English Journal
- The role of T-bet in obesity: lack of T-bet causes obesity in male mice.
- Kim KY, Jeong HJ, Kim HM.SourceDepartment of Pharmacology, College of Oriental Medicine, Kyung Hee University, Seoul 130-701, Republic of Korea.
- The Journal of nutritional biochemistry.J Nutr Biochem.2013 Jan;24(1):240-7. doi: 10.1016/j.jnutbio.2012.05.010. Epub 2012 Aug 15.
- The association of T helper (Th) 1 cells with obesity is well documented in both animals and humans. The T-box transcription factor (T-bet) is known as the transcription factor that is responsible for the development of Th1 cells. However, the role of T-bet in obesity has never been elucidated. The
- PMID 22901686
- Excess aldosterone-induced changes in insulin signaling molecules and glucose oxidation in gastrocnemius muscle of adult male rat.
- Selvaraj J, Sathish S, Mayilvanan C, Balasubramanian K.SourceDepartment of Endocrinology, Dr.ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Sekkizhar Campus, Taramani, Chennai, 600113, India.
- Molecular and cellular biochemistry.Mol Cell Biochem.2013 Jan;372(1-2):113-26. doi: 10.1007/s11010-012-1452-2. Epub 2012 Sep 25.
- Emerging evidences demonstrate that excess aldosterone and insulin interact at target tissues. It has been shown that increased levels of aldosterone contribute to the development of insulin resistance and thus act as a risk factor for the development of type-2 diabetes mellitus. However, the molecu
- PMID 23007523
Japanese Journal
- Clinical significance of screening for subclinical Cushing's disease in patients with pituitary tumors
- 耐糖能異常と思春期医学 (シンポジウム 糖尿病女性とウィメンズヘルスケア)
- 糖尿病と妊娠 : 日本糖尿病・妊娠学会誌 = Diabetes & pregnancy : the journal of the Japanese Society of Diabetes and Pregnancy 15(1), 46-49, 2015
- NAID 40020585275
- 多量飲酒の習慣がない人間ドック健診受診者における非アルコール性脂肪性肝疾患と腎結石の関連
Related Links
- Criteria [edit] According to the criteria of the World Health Organization and the American Diabetes Association, impaired glucose tolerance is defined as: [2] [3] [4] two-hour glucose levels of 140 to 199 mg per dL (7.8 to 11.0 mmol ...
- impaired glucose tolerance (IGT) [imperd′] Etymology: L, impejorare, to make worse; Gk, glykys, sweet; L, tolerare, to endure a condition in which fasting plasma glucose levels are higher than normal but lower than those diagnostic of ...
Related Pictures
★リンクテーブル★
[★]
[★]
- 英
- impaired glucose tolerance, IGT
- 関
- 糖尿病
[★]
- (価値・美点・見子などを)障害する、損なう、減ずる、害する、傷つける
- 関
- barrier、compromise、damage、difficulty、disorder、disturbance、dysfunction、foe、hindrance、impediment、lesion、obstacle
- 関
- (adj.) impaired, (n.)impairment
[★]
- 弱った、悪くなった、健康を害した、減少した、損なわれた、十分に機能を果たさない。
- (連語で)～に障害のある
[★]
耐性
- 関
- self-tolerance