heterogeneous-nuclear ribonucleoprotein group A-B

ヘテロ核リボヌクレオタンパク質グループA-B

WordNet

1. arrange into a group or groups; "Can you group these shapes together?"
2. (chemistry) two or more atoms bound together as a single unit and forming part of a molecule (同)radical, chemical group
3. any number of entities (members) considered as a unit (同)grouping
4. a set that is closed, associative, has an identity element and every element has an inverse (同)mathematical group
5. form a group or group together (同)aggroup
6. of or relating to or constituting the nucleus of an atom; "nuclear physics"; "nuclear fission"; "nuclear forces"
7. (weapons) deriving destructive energy from the release of atomic energy; "nuclear war"; "nuclear weapons"; "atomic bombs" (同)atomic
8. constituting or like a nucleus; "annexation of the suburban fringe by the nuclear metropolis"; "the nuclear core of the congregation"
9. of or relating to or constituting the nucleus of a cell; "nuclear membrane"; "nuclear division"
10. consisting of elements that are not of the same kind or nature; "the population of the United States is vast and heterogeneous" (同)heterogenous
11. the activity of putting things together in groups
12. a system for classifying things into groups (同)pigeonholing
13. the 2nd letter of the Roman alphabet (同)b
14. the blood group whose red cells carry the B antigen (同)type_B, group B

PrepTutorEJDIC

1. (…の)『群れ』,集まり,小集団《+of+名》 / (主義・系統・種類などを同じくする人・物の)『派』,『団体』 / (ポミュラーソング歌手の)グループ / (動・植物分類上の)群;(化学の)基,原子団;(地質学上の)界;(数学の)群;(言語学上の)語派 / …‘を'一群に集める,一団にする《+『名』+『together』》 / (系統的に)…‘を'分類する,調和よく配合する《+『名』+『together』》 / 集まる,群(集団)をなす
2. 『核の』,細胞核の / [『原子』]『核の』
3. 異種の,異質の / 異成分から成る,不均質の
4. グループに分けること;分類法 / (集まった物の)配置,配合

UpToDate Contents

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• 1. 消化器における神経内分泌腫瘍の発生の病理、分類、および重症度分類 pathology classification and grading of neuroendocrine tumors arising in the digestive system
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• 3. リードスタンバーグ細胞およびホジキンリンパ腫の病因 the reed sternberg cell and the pathogenesis of hodgkin lymphoma
• 4. 成人における全身性エリテマトーデスの診断および鑑別診断 diagnosis and differential diagnosis of systemic lupus erythematosus in adults
• 5. 糖尿病および遺伝的糖尿病症候群の分類 classification of diabetes mellitus and genetic diabetic syndromes

English Journal

• Oral squamous cancer cell exploits hnRNP A1 to regulate cell cycle and proliferation.

• Yu C1, Guo J1, Liu Y2, Jia J1, Jia R1, Fan M1.
• Journal of cellular physiology.J Cell Physiol.2015 Sep;230(9):2252-61. doi: 10.1002/jcp.24956.
• Oral squamous cell carcinoma (OSCC) is a common human malignant tumor with high mortality. So far, the molecular pathogenesis of OSCC remains largely unclear. Heterogeneous nuclear ribonucleoprotein (hnRNP) A1 is an important multi-function splicing factor and closely related to tumorigenesis. hnRNP
• PMID 25752295

• Splicing regulation in spinal muscular atrophy by an RNA structure formed by long-distance interactions.

• Singh NN1, Lee BM, Singh RN.
• Annals of the New York Academy of Sciences.Ann N Y Acad Sci.2015 Apr;1341:176-87. doi: 10.1111/nyas.12727. Epub 2015 Feb 27.
• Humans carry two copies of the survival motor neuron gene: SMN1 and SMN2. Loss of SMN1 coupled with skipping of SMN2 exon 7 causes spinal muscular atrophy (SMA), a leading genetic disease associated with infant mortality. Our discovery of intronic splicing silencer N1 (ISS-N1) is a promising target,
• PMID 25727246

• Regulation of RAGE splicing by hnRNP A1 and Tra2β-1 and its potential role in AD pathogenesis.

• Liu XY1, Li HL, Su JB, Ding FH, Zhao JJ, Chai F, Li YX, Cui SC, Sun FY, Wu ZY, Xu P, Chen XH.
• Journal of neurochemistry.J Neurochem.2015 Apr;133(2):187-98. doi: 10.1111/jnc.13069. Epub 2015 Mar 2.
• The receptor for advanced glycation end products (RAGE) gene expresses two major alternative splicing isoforms, full-length membrane-bound RAGE (mRAGE) and secretory RAGE (esRAGE). Both isoforms play important roles in Alzheimer's disease (AD) pathogenesis, either via interaction of mRAGE with β-am
• PMID 25689357

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★リンクテーブル★

リンク元	「ヘテロ核リボヌクレオタンパク質グループA-B」
関連記事	「group」「heterogeneous」「B」「grouping」「nuclear」

「ヘテロ核リボヌクレオタンパク質グループA-B」

　　[★]

英

heterogeneous-nuclear ribonucleoprotein group A-B

「group」

　　[★]

• n.

• 集団、グループ、(動物)群れ、(分類学)群、(化学)基

• v.

• 分類する、グループ化する

関

assortment、categorization、categorize、category、class、classification、classifier、classify、cluster、collective、grouping、herd、mass、population、sort、swarm、systematization、typing

　 　 　 　 　 　

「heterogeneous」

　　[★]

• adj.

• 不均一な、不均一性の、異種性の、異種起源の、異質な

関

alien、foreign、hetero、heterogeneity、heterogeneously、heterogenous、heterogenously、heterologous、heterologously、nonuniform、nonuniformity、ununiform、ununiformity、ununiformly

　 　

「B」

　　[★]

• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「grouping」

　　[★]

• n.

• 分類、グルーピング、グループ化、群化

関

assortment、categorization、categorize、category、class、classification、classifier、classify、group、grouped、sort、systematization、typing

　 　 　

「nuclear」

　　[★]

• adj.

• 核の、(生物)細胞核の、(物理)原子核の

関

cell nuclei、cell nucleus、nuclei、nucleo、nucleus