guanine nucleotide dissociation inhibitor

グアニンヌクレオチド解離阻害因子

WordNet

1. limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
2. control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
3. limit the range or extent of; "Contact between the young was inhibited by strict social customs"
4. a state in which some integrated part of a persons life becomes separated from the rest of the personality and functions independently (同)disassociation
5. (chemistry) the temporary or reversible process in which a molecule or ion is broken down into smaller molecules or ions
6. the act of removing from association
7. a substance that retards or stops an activity
8. a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA) (同)base
9. a purine base found in DNA and RNA; pairs with cytosine (同)G

PrepTutorEJDIC

1. 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
2. 分離[作用];解離
3. 抑制する人(物) / 化学反応抑制剤

UpToDate Contents

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• 1. 血管内皮機能および血栓溶解療法の基本的メカニズム vascular endothelial function and fundamental mechanisms of fibrinolysis thrombolysis
• 2. 免疫グロブリンの機能および臨床応用 function and clinical applications of immunoglobulins
• 3. 全身性エリテマトーデスの疫学および病因 epidemiology and pathogenesis of systemic lupus erythematosus
• 4. 尿酸による腎疾患 uric acid renal diseases
• 5. メトヘモグロビン血症の臨床的特徴、診断、および治療 clinical features diagnosis and treatment of methemoglobinemia

English Journal

• In vivo Rac/Rop localization as well as interaction with RhoGAP and RhoGDI in tobacco pollen tubes: analysis by low-level expression of fluorescent fusion proteins and bimolecular fluorescence complementation.

• Sun J1, Eklund DM1, Montes-Rodriguez A2, Kost B2.
• The Plant journal : for cell and molecular biology.Plant J.2015 Aug 7. doi: 10.1111/tpj.12961. [Epub ahead of print]
• Polarized Rac/Rop GTPase signaling plays a key role in polar cell growth, which is essential for plant morphogenesis. The molecular and cellular mechanisms responsible for the polarization of Rac/Rop signaling during polar cell growth are only partially understood. Mutant variants of Rac/Rop GTPases
• PMID 26252733

• Neuroglobin Plays a Protective Role in Arsenite-Induced Cytotoxicity by Inhibition of Cdc42 and Rac1GTPases in Rat Cerebellar Granule Neurons.

• Liu X1, Gao Y, An Y, Fu X, Li Y, Sun D, Wang J.
• Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.Cell Physiol Biochem.2015 Jul 10;36(4):1613-1627. [Epub ahead of print]
• BACKGROUND AND AIMS: We have previously shown that neuroglobin (Ngb) expression can be regulated by sodium arsenite (NaAsO2) exposure in rat cerebellar granule neurons (CGNs). However, the precise molecular mechanisms of Ngb action are largely unknown. Ras homolog (Rho) guanosine triphosphatases (Rh
• PMID 26160017

• Loss of Rho-GDIα sensitizes podocytes to lipopolysaccharide-mediated injury.

• Robins R1, Baldwin C1, Aoudjit L1, Gupta IR2, Takano T3.
• American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2015 Jun 1;308(11):F1207-16. doi: 10.1152/ajprenal.00225.2014. Epub 2014 Dec 10.
• Nephrotic syndrome is a disease of glomerular permselectivity that can arise as a consequence of heritable or acquired changes to the integrity of the glomerular filtration barrier. We recently reported two siblings with heritable nephrotic syndrome caused by a loss of function mutation in the gene
• PMID 25503727

Japanese Journal

• Concordance and interaction of guanine nucleotide dissociation inhibitor (RhoGDI) with RhoA in oogenesis and early development of the sea urchin

• ZAZUETA-NOVOA Vanesa,MARTINEZ-CADENA Guadalupe,WESSEL Gary M.,ZAZUETA-SANDOVAL Roberto,CASTELLANO Laura,GARCIA-SOTO Jesus
• Development, growth & differentiation 53(3), 427-439, 2011-04-01
• NAID 10028202894

• Proteomic Analysis of Focal Cerebral Ischemic Injury in Male Rats

• KOH Phil-Ok
• Journal of Veterinary Medical Science advpub(0), 0911180043, 2010
• … Among these proteins, 60 kDa heat shock protein, dehydropyrimidinase-related protein 2, t-complex protein 1, and Rho GDP dissociation inhibitor levels were significantly increased in MCAO group compared to those of the sham group. … In contrast, thioredoxin, peroxiredoxin-2, stathmin, ubiquitin carboxy-terminal hydrolase L1, guanine nucleotide-binding protein α, pyridoxal-5-phosphate phosphatase, and apoplipoprotein A-I levels were significantly decreased in MCAO group. …
• NAID 130000134527

Related Links

• Guanosine nucleotide dissociation inhibitors - Wikipedia, the free ...

The Guanosine nucleotide dissociation inhibitors (GDIs), bind to the GDP-bound form of Rho and Rab small GTPases and not only prevent exchange (maintaining the small GTPase in an off-state), but also prevent the small GTPase from ...

• Molecular Dissection of Guanine Nucleotide Dissociation Inhibitor ...

Abstract. Guanine nucleotide dissociation inhibitor (GDI) is an essential protein required for the recycling of Rab GTPases mediating the targeting and fusion of vesicles in the exocytic and endocytic pathways. Using site-directed mutagenesis ...

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★リンクテーブル★

リンク元	「グアニンヌクレオチド解離阻害因子」
関連記事	「inhibit」「inhibitor」「dissociation」「guanine nucleotide」

「グアニンヌクレオチド解離阻害因子」

　　[★]

英

guanine nucleotide dissociation inhibitor

「inhibit」

　　[★]

• v.

• 抑制する、阻害する、阻止する

関

abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression

　 　 　 　

「inhibitor」

　　[★]

• n.

• 阻害剤、阻害薬、抑制薬、抑制剤、(内在性物質について)インヒビター、抑制物質

関

blocker、depressant、suppressant

　 　

「dissociation」

　　[★]

• n.

• 解離

関

detachment、dissection、dissociate、dissociative disorder、dissociative reaction、fugue、maceration、unbinding

　 　 　 　

「guanine nucleotide」

　　[★]

• グアニンヌクレオチド