WordNet

a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA) (同)base
a purine base found in DNA and RNA; pairs with cytosine (同)G

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D'Arcangelo JG, Stahmer KR, Miller EA.SourceDepartment of Biological Sciences, Columbia University, New York, NY, USA.
Biochimica et biophysica acta.Biochim Biophys Acta.2013 Nov;1833(11):2464-72. doi: 10.1016/j.bbamcr.2013.02.003. Epub 2013 Feb 15.
Vesicle trafficking from the endoplasmic reticulum (ER) is a vital cellular process in all eukaryotes responsible for moving secretory cargoes from the ER to the Golgi apparatus. To accomplish this feat, the cell employs a set of conserved cytoplasmic coat proteins - the coat protein II (COPII) comp
PMID 23419775

Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.

Montero JC, Seoane S, Pandiella A.SourceInstituto de Biología Molecular y Celular del Cáncer, CSIC-Universidad de Salamanca, Spain.
Cellular signalling.Cell Signal.2013 Nov;25(11):2281-9. doi: 10.1016/j.cellsig.2013.07.018. Epub 2013 Jul 27.
Former reports demonstrated that P-Rex, a Rac guanine nucleotide exchange factor (GEF), participated in signaling upon activation of the ErbB receptor tyrosine kinases (RTKs). Activation of ErbB receptors turned on a phosphorylation/dephosphorylation cycle of P-Rex in which stimulation of serine(116
PMID 23899556

Chow CR, Suzuki N, Kawamura T, Hamakubo T, Kozasa T.SourceDepartment of Pharmacology, University of Illinois at Chicago, 835 S. Wolcott Avenue Room E403 (m/c 868), Chicago, IL 60612, USA; Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan. Electronic address: crchow@uic.edu.
Cellular signalling.Cell Signal.2013 Nov;25(11):2085-92. doi: 10.1016/j.cellsig.2013.06.012. Epub 2013 Jun 29.
p115RhoGEF is a member of a family of Rho-specific guanine nucleotide exchange factors that also contains a regulator of G protein signaling homology domain (RH-RhoGEFs) that serves as a link between Gα13 signaling and RhoA activation. While the mechanism of regulation of p115RhoGEF by Gα13 is bec
PMID 23816534

The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation

Matsuda Takenori,Yanase Shougo,Takaoka Akinori,Maruyama Mitsuo
Immunity & Ageing 12, 1, 2015-02-22
… We originally cloned and identified murine Zizimin2 (Ziz2, Dock11) as a guanine nucleotide exchange factor (GEF) for Cdc42 and demonstrated that it activated the formation of filopodia. …
NAID 120005593441

Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency

, , , , , , , , , , , , ,
Endocrine Journal 62(2), 153-160, 2015
… Mass spectrometric analysis revealed the 51-kDa band contained Rab guanine nucleotide dissociation inhibitor (GDI) alpha. …
NAID 130004770481

長野真,十島純子,十島二朗
薬学雑誌. 乙号 135(3), 483-492, 2015
… In yeast, the secretory pathway is regulated by sequential activation and inactivation (the so-called Rab cascade) of three types of yeast Rab protein -Ypt1p, Ypt31p/32p and Sec4p -via specific guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). …
NAID 130004756514