WordNet

a class of transferases that catalyze transamination (that transfer an amino group from an amino acid to another compound) (同)aminotransferase, aminopherase
a crystalline amino acid that occurs in many proteins

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1. 肝細胞障害を検出するための肝臓生化学検査 liver biochemical tests that detect injury to hepatocytes
2. 高用量メトトレキサートの治療使用および毒性 therapeutic use and toxicity of high dose methotrexate
3. 筋萎縮性側索硬化症の病態修飾療法 disease modifying treatment of amyotrophic lateral sclerosis
4. α-1アンチトリプシン欠乏症の臨床症状、診断、および自然経過 clinical manifestations diagnosis and natural history of alpha 1 antitrypsin deficiency
5. シアン化物中毒 cyanide poisoning

Targeted Gene Silencing of TLR4 Using Liposomal Nanoparticles for Preventing Liver Ischemia Reperfusion Injury.

Jiang N, Zhang X, Zheng X, Chen D, Zhang Y, Siu LK, Xin HB, Li R, Zhao H, Riordan N, Ichim TE, Quan D, Jevnikar AM, Chen G, Min W.SourceMulti-Organ Transplant Program, London Health Sciences Centre, London, Canada Department of Surgery, Pathology, and Medicine, University of Western Ontario, London, Canada Liver Transplant Center, The Third Affiliated Hospital of Sun Yat-sen University, Transplantation Research Institute of Sun Yat-sen University, Guangzhou, China Institute of Translational Medicine, Nanchang University, Nanchang, China Department of Liver Surgery, Peking Union Medical College Hospital, Beijing, China Medistem Panama City of Knowledge, Clayton, Republic of Panama.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.Am J Transplant.2011 Sep;11(9):1835-1844. doi: 10.1111/j.1600-6143.2011.03660.x. Epub 2011 Jul 27.
RNAi-based therapy is a promising strategy for the prevention of ischemia-reperfusion injury (IRI). However, systemic administration of small interfering RNA (siRNA) may cause globally nonspecific targeting of all tissues, which impedes clinical use. Here we report a hepatocyte-specific delivery sys
PMID 21794086

Kim JY, Chun S, Bang MS, Shin HI, Lee SU.SourceDepartment of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul, Korea; Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul, Korea.
Archives of physical medicine and rehabilitation.Arch Phys Med Rehabil.2011 Sep;92(9):1359-63.
Kim JY, Chun S, Bang MS, Shin H-I, Lee S-U. Safety of low-dose oral dantrolene sodium on hepatic function.OBJECTIVE: To investigate the incidence of hepatobiliary dysfunction after administration of low-dose dantrolene sodium.DESIGN: A retrospective survey of medical records.SETTING: One secondary a
PMID 21878205

Interrelationship between gluconeogenesis and ureogenesis in rats fed a high fat, carbohydrate-free diet.

高瀬幸子
日本栄養・食糧学会誌 38(2), 109-116, 1985
… Despite elevated gluconeogenesis in those groups, the activity of hepatic enzyme of glutamic alanine transaminase (GAT), pyruvate carboxylase (PC) and arginase was different between rats fed the HF-corn oil, HF-MCT and HP diets. …
NAID 130000861556

CHANGES IN THE CARBOHYDRATES, PROTEINS AND NUCLEIC ACIDS IN THE OVULES OF ZEPHYRANTHES LANCASTERI AT DIFFERENT STAGES OF MATURATION

JOHRI M.M.,MAHESHWARI S.C.
Plant and cell physiology 7(3), 385-393, 1966-09
… The activities of amylases, glutamic-alanine transaminase, ribonuclease and deoxyribonuclease were also studied. … The glutamic-alanine transaminase activity appears to be exclusively localized in the endosperm and is absent from the embryo. …
NAID 110003721717

CHANGES IN THE CARBOHYDRATES, PROTEINS AND NUCLEIC ACIDS DURING SEED DEVELOPMENT IN OPIUM POPPY

JOHRI M.M.,MAHESHWARI SATISH C.
Plant and cell physiology 7(1), 35-47, 1966-03
… The activity of glutamic-alanine transaminase increases concurrently with the increase of protein in the ovules. …
NAID 110003721684

英: alanine aminotransferase, L-alanine aminotransferase, ALT
同: グルタミン酸ピルビン酸トランスアミナーゼ glutamic-pyruvic transaminase, GPT; グルタミン酸アラニントランスアミナーゼ glutamic-alanine transaminase、L-アラニン:2-オキソグルタル酸アミノトランスフェラーゼ L-alanine:2-oxoglutarateaminotransferase
関: アスパラギン酸アミノ基転移酵素 AST、マクロALT。アミノ転移

可逆的アミノ基転移反応を触媒する
L-アラニン（L-alanine）＋2-オキソグルタル酸（2-oxoglutarate）＝ピルビン酸（pyruvate）＋L-グルタミン酸（L-glutamate
補酵素：ピリドキサールリン酸（VB6）補酵素
組織の炎症や挫滅により血中に逸脱
消化管から由来する大量のアラニンを肝臓でピルビン酸へと変換し，糖新生の基質として供給
全身に存在するが、特に肝臓に多い。

急性ウイルス肝炎