fluphenazine

フルフェナジン  

WordNet

  1. tranquilizer used to treat psychotic disorders

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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/22 13:52:23」(JST)

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English Journal

  • Phenothiazine-derived antipsychotic drugs inhibit dynamin and clathrin-mediated endocytosis.
  • Daniel JA1,2, Chau N1, Abdel-Hamid MK3, Hu L4, von Kleist L5, Whiting A1, Krishnan S1, Maamary P1, Joseph SR4, Simpson F4, Haucke V5, McCluskey A3, Robinson PJ1.
  • Traffic (Copenhagen, Denmark).Traffic.2015 Jun;16(6):635-54. doi: 10.1111/tra.12272. Epub 2015 Apr 9.
  • Chlorpromazine is a phenothiazine-derived antipsychotic drug (APD) that inhibits clathrin-mediated endocytosis (CME) in cells by an unknown mechanism. We examined whether its action and that of other APDs might be mediated by the GTPase activity of dynamin. Eight of eight phenothiazine-derived APDs
  • PMID 25693808
  • Fluphenazine.HCl and epigallocatechin gallate modulate the rate of formation and structural properties of apolipoprotein C-II amyloid fibrils.
  • Zlatic CO, Mao Y, Ryan TM, Mok YF, Roberts BR, Howlett GJ, Griffin MD.
  • Biochemistry.Biochemistry.2015 May 29. [Epub ahead of print]
  • Protein misfolding and aggregation, leading to amyloid fibril formation, are characteristic of many devastating and debilitating amyloid diseases. Accordingly, there is significant interest in the mechanisms underlying amyloid fibril formation and identification of possible intervention tools. Small
  • PMID 26021642
  • Dose escalation of antipsychotic drugs in schizophrenia: A meta-analysis of randomized controlled trials.
  • Dold M1, Fugger G1, Aigner M2, Lanzenberger R1, Kasper S3.
  • Schizophrenia research.Schizophr Res.2015 May 22. pii: S0920-9964(15)00219-4. doi: 10.1016/j.schres.2015.04.024. [Epub ahead of print]
  • BACKGROUND: Non-response to an initial antipsychotic trial emerges frequently in the pharmacological management of schizophrenia. Increasing the dose (high-dose treatment, dose escalation) is an often applied strategy in this regard, but there are currently no meta-analytic data available to ascerta
  • PMID 26008883

Japanese Journal

  • Comparison of Cytochrome P450 Mediated Metabolism of Three Central Nervous System Acting Drugs
  • Attia Tamer Zekry,Yamashita Taku,Miyamoto Masayoshi [他]
  • Chemical and pharmaceutical bulletin 60(12), 1544-1549, 2012-12
  • NAID 40019497219
  • Comparison of Cytochrome P450 Mediated Metabolism of Three CNS Acting Drugs
  • Zekry Attia Tamer,Yamashita Taku,Miyamoto Masayoshi,Koizumi Atsushi,Yasuhara Yuki,Node Jun-ichi,Erikawa Yumi,Komiyama Yumi,Horii Chiaki,Yamada Mayu,Ahmed Omar Mahmoud,Hassan Abdelmageed Osama,Mohamed Derayea Sayed,Uno Tadayuki
  • Chemical and Pharmaceutical Bulletin 2012(0), 2012
  • … In this study, the metabolic activities of three major hepatic CYP isoforms (2C19, 2D6, and 3A4) were investigated on structurally different central nervous system (CNS) acting drugs, amitriptyline, fluphenazine, and dothiepin. … By using our novel in vitro evaluation system, we could compare the kinetic parameters for the metabolism of fluphenazine and dothiepin for the first time. …
  • NAID 130001852550
  • Simple and simultaneous determination for twelve phenothiazines in human serum by reversed-phase high-performance liquid chromatography
  • TANAKA Einosuke,NAKAMURA Takako,TERADA Masaru,SHINOZUKA Tatsuo,HASHIMOTO Chikako,KURIHARA Katsuyoshi,HONDA Katsuya
  • Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 854(1), 116-120, 2007-07-01
  • … A high-performance liquid chromatographic method has been developed for the simultaneous analysis of the 12 phenothiazines (chlorpromazine, fluphenazine, levomepromazine, perazine, perphenazine, prochlorperazine, profenamine, promethazine, propericiazine, thioproperazine, thioridazine and trifluoperazine) in human serum using HPLC/UV. …
  • NAID 10025805017

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fluphenazine 【名】《化》フルフェナジン - アルクがお届けする進化するオンライン英和・和英辞書データベース。一般的な単語や連語から、イディオム、専門用語、スラングまで幅広く収録。
フルフェナジン fluphenazine フェノチアジン系精神神経用剤 1172 【組成】 [散]:マレイン酸エステル をフルフェナジンとして0.2% [錠]:1錠中マレ イン酸エステルをフルフェナジンとし て0.25 mg,0.5 mg,1 mg [注]油性:1バイアル(1 ml ...



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リンク元フルフェナジン
拡張検索fluphenazine maleate

フルフェナジン」

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fluphenazine
デカン酸フルフェナジン fluphenazine decanoate
マレイン酸フルフェナジン fluphenazine maleate
塩酸フルフェナジン fluphenazine hydrochloride
トリラホン Trilafonフルデカシンフルメジン
Permitil, Prolixin。ペルフェナジン
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fluphenazine maleate」

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