実験的薬剤性糖尿病
WordNet
- reason or establish by induction
- cause to arise; "induce a crisis" (同)bring_on
- produce electric current by electrostatic or magnetic processes (同)induct
- cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
- cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
- to conduct a test or investigation; "We are experimenting with the new drug in order to fight this disease"
- the act of conducting a controlled test or investigation (同)experimentation
- a venture at something new or different; "as an experiment he decided to grow a beard"
- the testing of an idea; "it was an experiment in living"; "not all experimentation is done in laboratories" (同)experimentation
- try something new, as in order to gain experience; "Students experiment sexually"; "The composer experimented with a new style" (同)try out
- relating to or based on experiment; "experimental physics"
- relying on observation or experiment; "experimental results that supported the hypothesis" (同)data-based, observational
- of the nature of or undergoing an experiment; "an experimental drug"
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
- a polygenic disease characterized by abnormally high glucose levels in the blood; any of several metabolic disorders marked by excessive urination and persistent thirst
PrepTutorEJDIC
- 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
- (…の)『実験』,試み《+『in』(『on, with』)+『名』》 / (…の)実験をする《+『on(upon, with)』+『名』》
- 実験の,実験に基づく: / 実験に使われる,実験用の / 実験的な,試験的な
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
- 糖尿病(尿に糖が異常に出る病気)
UpToDate Contents
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English Journal
- Features of Autoimmune Hepatitis in Patients With Drug-induced Liver Injury.
- de Boer YS1, Kosinski AS2, Urban TJ3, Zhao Z4, Long N3, Chalasani N5, Kleiner DE6, Hoofnagle JH7; Drug-Induced Liver Injury Network.
- Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.Clin Gastroenterol Hepatol.2017 Jan;15(1):103-112.e2. doi: 10.1016/j.cgh.2016.05.043. Epub 2016 Jun 14.
- BACKGROUND & AIMS: Drug-induced liver injury (DILI) has features similar to those of other liver diseases including autoimmune hepatitis (AIH). We aimed to characterize the clinical and autoimmune features of liver injury caused by nitrofurantoin, minocycline, methyldopa, or hydralazine.METHODS:
- PMID 27311619
- Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-wide Association Study.
- Nicoletti P1, Aithal GP2, Bjornsson ES3, Andrade RJ4, Sawle A1, Arrese M5, Barnhart HX6, Bondon-Guitton E7, Hayashi PH8, Bessone F9, Carvajal A10, Cascorbi I11, Cirulli ET6, Chalasani N12, Conforti A13, Coulthard SA14, Daly MJ15, Day CP14, Dillon JF16, Fontana RJ17, Grove JI2, Hallberg P18, Hernández N19, Ibáñez L20, Kullak-Ublick GA21, Laitinen T22, Larrey D23, Lucena MI4, Maitland-van der Zee AH24, Martin JH25, Molokhia M26, Pirmohamed M27, Powell EE28, Qin S29, Serrano J30, Stephens C4, Stolz A31, Wadelius M18, Watkins PB32, Floratos A1, Shen Y1, Nelson MR33, Urban TJ34, Daly AK35; International DILI consortium (iDILIC), Drug-induced liver injury network (DILIN) investigators and International Serious Adverse Events Consortium (iSAEC).
- Gastroenterology.Gastroenterology.2016 Dec 30. pii: S0016-5085(16)35530-5. doi: 10.1053/j.gastro.2016.12.016. [Epub ahead of print]
- BACKGROUND & AIMS: We performed a genome-wide association study (GWAS) to identify genetic risk factors for drug-induced liver injury (DILI) from licensed drugs without previously reported genetic risk factors.METHODS: We performed a GWAS of 862 persons with DILI and 10588 population-matched con
- PMID 28043905
- Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice.
- Ramakrishnan P1, Yui MA2, Tomalka JA3, Majumdar D2, Parameswaran R3, Baltimore D4.
- Diabetes.Diabetes.2016 Aug;65(8):2367-79. doi: 10.2337/db15-1607. Epub 2016 May 23.
- The nuclear factor-κB protein c-Rel plays a critical role in controlling autoimmunity. c-Rel-deficient mice are resistant to streptozotocin-induced diabetes, a drug-induced model of autoimmune diabetes. We generated c-Rel-deficient NOD mice to examine the role of c-Rel in the development of spontan
- PMID 27217485
Japanese Journal
- Pancreatic β Cell-specific Expression of Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes
- The global epidemiology of diabetes mellitus.
Related Links
- 1. Gen Physiol Biophys. 1999 Oct;18 Spec No:54-62. Streptozotocin-induced experimental diabetes in male Wistar rats. Gajdosík A, Gajdosíková A, Stefek M, Navarová J, Hozová R. The aim of the present work was to test the ...
- 1. Baillieres Clin Endocrinol Metab. 1992 Oct;6(4):849-66. Drug-induced diabetes. Ferner RE. The only drugs which commonly cause diabetes during therapeutic use are the anti-hypertensive vasodilator diazoxide, and corticosteroids ...
★リンクテーブル★
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- 英
- experimental drug-induced diabetes
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- 誘発する、誘導する、誘起する、導入する、引き起こす
- 関
- cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark
[★]
- 関
- a priori、empiric、empirical、empirically、experiment、experimentally
[★]
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- hypercalcaemia induced pancreatitis 高カルシウム血症による膵炎
[★]
- 関
- 糖尿病 diabetes mellitus DM
[★]
- 関
- experimental