クリオピリン周期熱症候群
WordNet
- having partial rights and privileges or subordinate status; "an associate member"; "an associate professor"
- a person who joins with others in some activity or endeavor; "he had to consult his associate before continuing"
- a person with subordinate membership in a society, institution, or commercial enterprise; "associates in the law firm bill at a lower rate than do partners"
- any event that usually accompanies or is closely connected with another; "first was the lightning and then its thunderous associate"
- make a logical or causal connection; "I cannot connect these two pieces of evidence in my mind"; "colligate these facts"; "I cannot relate these events at all" (同)tie_in, relate, link, colligate, link up, connect
- a unit of geological time during which a system of rocks formed; "ganoid fishes swarmed during the earlier geological periods" (同)geological period
- (ice hockey) one of three divisions into which play is divided in hockey games
- the end or completion of something; "death put a period to his endeavors"; "a change soon put a period to my tranquility"
- the interval taken to complete one cycle of a regularly repeating phenomenon
- a punctuation mark (.) placed at the end of a declarative sentence to indicate a full stop or after abbreviations; "in England they call a period a stop" (同)point, full_stop, stop, full point
- happening or recurring at regular intervals; "the periodic appearance of the seventeen-year locust" (同)periodical
- recurring or reappearing from time to time; "periodic feelings of anxiety" (同)occasional
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
PrepTutorEJDIC
- 〈人〉'を'(…の)『仲間に加える』,(…に)連合させる《+『名』〈人〉+『with』+『名』》 / (…と)…'を'結びつけて考える(起こす)《+『名』+『with』+『名』》 / (…と)『仲間になる』,交際する《+『with』+『名』》 / (…と)合体する,提携する《+『with』+『名』》 / 『仲間』,『同僚』;組合員 / 準会員 / 付属物;連想されるもの / 連合した;仲間の,同僚の / 補助の,準…
- (あることが続く)『期間』 / (歴史的な)『時代』 / (試合の)『一区切り』,ピリオド / 授業時間,時限: / (循環して起こる現象などの)周期 / (回転運動などの)周期 / 紀(地質時代の区分の一つ;era(代)の下,epoch(世)の上) / 《おもに米》『ピリオド』,終止符(《英》full stop;Mr.,U.S.など略語の符号(.)も含む) / 《複数形で》《文》掉尾(とうび)文(多くの節から成り,論理的に緊密な構成をもっている文) / 《名詞の前にのみ用いて》ある時代[特有]の,時代物の / (文の終わりに感嘆詞的に)以上,終わり・月経(期間)
- 定期的な,周期的な / ときぎき起こる: / 掉尾(とうび)的の:
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2016/04/19 22:50:06」(JST)
[Wiki en表示]
Cryopyrin-associated periodic syndrome |
Classification and external resources |
MeSH |
D056587 |
[edit on Wikidata]
|
Cryopyrin-associated periodic syndrome (CAPS) is a spectrum of autoinflammatory syndromes including familial cold autoinflammatory syndrome (FCAS, formerly termed familial cold-induced urticaria), the Muckle-Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease (NOMID, also called chronic infantile neurologic cutaneous and articular syndrome or CINCA). They share many clinical features.
These syndromes are associated with mutations in NLRP3, the gene encoding cryopyrin. This is a component of the interleukin 1 inflammasome, and mutations lead to unregulated production of interleukin 1β. Monoclonal antibodies against interleukin 1β (such as canakinumab), other interleukin 1 binding proteins (such as rilonacept), or interleukin 1 receptor antagonist (for example anakinra) can be used to treat these disorders.
References
- Kubota T, Koike R. Cryopyrin-associated periodic syndromes: background and therapeutics. Mod Rheumatol. 2010 Jun;20(3):213-21
- Autoinflammatory Alliance CAPS Guidebook
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1β.
- Rondeau JM1, Ramage P1, Zurini M1, Gram H1.
- mAbs.MAbs.2015 Nov 2;7(6):1151-60. doi: 10.1080/19420862.2015.1081323. Epub 2015 Aug 18.
- Interleukin-1β (IL-1β) plays a key role in autoinflammatory diseases, such as systemic juvenile idiopathic arthritis (sJIA) or cryopyrin-associated periodic syndrome (CAPS). Canakinumab, a human monoclonal anti-IL-1β antibody, was recently approved for human use under the brand name Ilaris®. Can
- PMID 26284424
- Phenotypic and genotypic characteristics of cryopyrin-associated periodic syndrome: a series of 136 patients from the Eurofever Registry.
- Levy R1, Gérard L2, Kuemmerle-Deschner J3, Lachmann HJ4, Koné-Paut I5, Cantarini L6, Woo P7, Naselli A8, Bader-Meunier B1, Insalaco A9, Al-Mayouf SM10, Ozen S11, Hofer M12, Frenkel J13, Modesto C14, Nikishina I15, Schwarz T16, Martino S17, Meini A18, Quartier P1, Martini A19, Ruperto N8, Neven B1, Gattorno M8; for PRINTO and Eurofever.
- Annals of the rheumatic diseases.Ann Rheum Dis.2015 Nov;74(11):2043-9. doi: 10.1136/annrheumdis-2013-204991. Epub 2014 Jul 18.
- OBJECTIVE: To evaluate genetic, demographic and clinical features in patients with cryopyrin-associated periodic syndrome (CAPS) from the Eurofever Registry, with a focus on genotype-phenotype correlations and predictive disease severity markers.METHODS: A web-based registry retrospectively collecte
- PMID 25038238
- Musculoskeletal Symptoms in Patients With Cryopyrin-Associated Periodic Syndromes: A Large Database Study.
- Houx L1, Hachulla E2, Kone-Paut I3, Quartier P4, Touitou I5, Guennoc X6, Grateau G7, Hamidou M8, Neven B9, Berthelot JM8, Lequerré T10, Pillet P11, Lemelle I12, Fischbach M13, Duquesne A14, Le Blay P15, Le Jeunne C16, Stirnemann J17, Bonnet C18, Gaillard D19, Alix L20, Touraine R21, Garcier F22, Bedane C19, Jurquet AL23, Duffau P24, Smail A25, Frances C26, Grall-Lerosey M11, Cathebras P27, Tran TA28, Morell-Dubois S29, Pagnier A30, Richez C12, Cuisset L31, Devauchelle-Pensec V32.
- Arthritis & rheumatology (Hoboken, N.J.).Arthritis Rheumatol.2015 Nov;67(11):3027-36. doi: 10.1002/art.39292.
- OBJECTIVE: To determine the type and frequency of musculoskeletal symptoms at onset and during followup of cryopyrin-associated periodic syndromes (CAPS).METHODS: We retrospectively recorded the articular and muscular symptoms of patients with CAPS followed up in French hospitals. Data were presente
- PMID 26245507
Japanese Journal
- 臨床免疫・アレルギー科 = Clinical immunology & allergology 65(1), 94-98, 2016-01
- NAID 40020720028
Related Links
- is a subgroup of the hereditary periodic fever syndromes. ... Cryopyrin Associated Periodic Syndromes (CAPS): Overview TOPICS: Etiology of CAPS Autoinflammatory vs. Autoimmune Diseases Role of the Inflammasome and NLRP3 Gene Mutations
- About cryopyrin-associated periodic syndromes (CAPS) Cryopyrin-associated periodic syndromes are members of a family of autoinflammatory diseases. CAPS is a rare, autosomal dominant disease consisting of three ...
★リンクテーブル★
[★]
- 英
- cryopyrin-associated periodic syndrome, CAPS
- 関
- 自己炎症性周期性発熱症候群
[★]
- 結合する、連合させる。連想によって結びつける。(人を)仲間/友達などとしての関係に置く。(化)会合させる
- 仲間/友人などとして交際する(with)。一つにまとめる、連合する
- 仕事仲間、提携者、同僚。友人、朋友。準会員。従業員、社員
- 密接な蒸す偽付きのある物、付随する物、つきもの。準国家
- 連想によって心に浮かぶ言葉/思い、連想物
- 仲間の、同僚の。製紙機械員に次ぐ資格の
- 付随する、連想される
- 関
- accompany、association、associative、attach、bearing、bind、binding、bond、bonding、coassemble、colleague、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、correlate、correlation、couple、dock、engage、engagement、federation、implication、join、joint、ligate、link、linkage、peer、pertinent、reference、relate、relation、relationship、relative、relevance、relevant、symphysial、union
[★]
- 周期的な、(天)周期運動をする、周期手金あ。定期の、定時の。間欠的な、断続的な。
- 関
- cyclic, cyclical, cyclically, cyclicity, periodical, periodically, periodicity, regular, regularly, rhythmic
[★]
- 関
- duration、phase、stage、term、time
[★]
- 関
- concomitant、erratic、erratically
- associate
[★]