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1. 中心静脈アクセスの概要overview of central venous access [show details]
… Central venous access is a commonly performed procedure with approximately 8 percent of hospitalized patients requiring central venous access during the course of their hospital stay. More than five million …
2. 網膜中心動脈閉塞症および網膜動脈分枝閉塞症central and branch retinal artery occlusion [show details]
…percent of patients who have a cilioretinal artery feeding the macular region. These patients have a central area of visual field remaining, usually approximately 5° in the vertical dimension and up to 15° in …
3. 小児における中枢神経系の急性脱髄の鑑別診断differential diagnosis of acute central nervous system demyelination in children [show details]
… mitochondrial disease, and certain leukodystrophies . Large areas of tumefactive demyelination can give rise to concern for possible central nervous system lymphoma or high-grade glioma . In the absence …
4. 血液透析における緊急および長期ブラッドアクセスとしての中心静脈カテーテルcentral catheters for acute and chronic hemodialysis access [show details]
… to venous congestion. Central vein thrombosis usually responds to anticoagulation or thrombolytic therapy . Percutaneous transluminal angioplasty can be performed to dilate areas of stenosis . Lesions …
5. 成人における中枢気道閉塞の臨床症状、診断的評価およびマネージメントclinical presentation diagnostic evaluation and management of central airway obstruction in adults [show details]
… Central airway obstruction – Central airway obstruction (CAO) refers to the obstruction… may reveal >50 percent reduction in cross-sectional area on expiration suggestive of tracheobronchomalacia…

English Journal

A panel of serum exosomal microRNAs as predictive markers for chemoresistance in advanced colorectal cancer.

Jin G, Liu Y, Zhang J, Bian Z, Yao S, Fei B, Zhou L, Yin Y, Huang Z.
Cancer chemotherapy and pharmacology. 2019 May;().
Chemoresistance is a common problem for cancer treatment worldwide. Circulating exosomal microRNAs (miRNAs) have been considered as promising biomarkers of cancers. However, few studies have assessed the relationship between serum/plasma exosomal microRNAs and chemoresistance in colorectal cancer (C
PMID 31089750

ATP in the lateral hypothalamus/perifornical area enhances the CO chemoreflex control of breathing.

da Silva EN, Horta-Júnior JAC, Gargaglioni LH, Dias MB.
Experimental physiology. 2018 12;103(12)1679-1691.
What is the central question of this study? ATP is known to modulate the chemosensitivity of some brain areas. However, whether the ATP contributes specifically to the mechanism of chemoreception in the lateral hypothalamus/perifornical area (LH/PFA) remains to be determined. What is the main findin
PMID 30242927

The Role of Allogeneic Transplantation for Multiple Myeloma in the Era of Novel Agents: A Study from the Japanese Society of Myeloma.

Kawamura K, Tsukada N, Kanda Y, Ikeda T, Yoshida A, Ueda Y, Ishida T, Suzuki K, Murakami H.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 2018 07;24(7)1392-1398.
Although allogeneic hematopoietic stem cell transplantation (allo-HSCT) is considered a potentially curative therapy for patients with multiple myeloma, the role of allo-HSCT remains unclear in the novel agent era. We conducted a retrospective study of 65 patients with multiple myeloma who underwent
PMID 29555314

Japanese Journal

Chemotherapy for primary mediastinal yolk sac tumor in a patient undergoing chronic hemodialysis: a case report

Hirakawa Haruki,Nakashima Chiho,Nakamura Tomomi,Masuda Masanori,Funakoshi Taro,Nakagawa Shunsaku,Horimatsu Takahiro,Matsubara Kazuo,Muto Manabu,Kimura Shinya,Sueoka-Aragane Naoko
Journal of Medical Case Reports (11), 2017-02-16
… Although chemosensitive cancers, such as germ cell tumors, treated with chemotherapy should have sufficient dose intensity maintained to achieve the desired effect, many patients with cancer undergoing hemodialysis might be under-treated because the pharmacokinetics of anti-cancer drugs in such patients remains unknown. …
NAID 120005980830

肥満治療の新たな展望(指定発言)(内科領域における全人的医療)(第31回日本心身医学会総会)

吉松博信,坂田利家
心身医学 31(3), 245-251, 1991
… The central nervous system is important in coordinating behavioral and autonomic control of homeostasis in response to outer and inner environmental changes. … Chemosensitive neurons in the lateral hypothalamic area (LHA) that receive and respond to humoral information, such as blood-borne chemicals and hormones, have been identified in this area. …
NAID 110001117894

Inspiratory response to occlusion of arteries in the ventral surface of the medulla in anesthetized cats.

KUWANA SHUN-ICHI,NATSUI TEIJIRO
The Tohoku Journal of Experimental Medicine 156(Suppl), 1-9, 1988
… By the occlusion of arteries in the ventral surface of the medulla, the blood supply to the central chemoreceptor for respiration was examined in anesthetized, paralyzed and peripheral chemodenervated cats. … These different results may be due to the complexity of the central chemosensitive structure or of the central vascular system. …
NAID 130003494061