WordNet
- invest with or as with a body; give body to (同)personify
- the external structure of a vehicle; "the body of the car was badly rusted"
- the main mass of a thing
- a natural object consisting of a dead animal or person; "they found the body in the lake" (同)dead body
- the entire structure of an organism (an animal, plant, or human being); "he felt as if his whole body were on fire" (同)organic structure, physical structure
- a collection of particulars considered as a system; "a body of law"; "a body of doctrine"; "a body of precedents"
- a group of persons associated by some common tie or occupation and regarded as an entity; "the whole body filed out of the auditorium"; "the student body"; "administrative body"
- an individual 3-dimensional object that has mass and that is distinguishable from other objects; "heavenly body"
- the central message of a communication; "the body of the message was short"
PrepTutorEJDIC
- 〈C〉『身体』,肉体 / 〈C〉(人・動物の)『胴体』 / 〈C〉)物の)『主要部』,本体《+『of』+『名』》 / 〈C〉(…の)『団体』,群れ:(…のたくさんの)集まり《+『of』+『名』》 / 〈C〉物体,…体 / 〈U〉実質;(酒・味などの)こく / 〈C〉《話》人
- 《英話》人;(特に)男
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/12/14 12:43:41」(JST)
[Wiki en表示]
Aortic body |
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The thoracic aorta, heart and other great vessels. (Aortic body not visible, but arch of aorta labeled at center.) |
Latin |
corpora paraaortica |
Gray's |
subject #277 1277 |
Nerve |
vagus nerve [1] |
MeSH |
Aortic+Bodies |
In the human heart, the aortic body ("glomus aorticum") is one of several small clusters of chemoreceptors, baroreceptors, and supporting cells located along the aortic arch.
Contents
- 1 Function
- 2 Disorders
- 3 Nomenclature
- 4 References
- 5 See also
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Function
It measures changes in blood pressure and the composition of arterial blood flowing past it, including the partial pressures of oxygen and carbon dioxide and pH.[2] The chemoreceptors responsible for sensing changes in blood gases are called glomus cells.
It gives feedback to the medulla oblongata via the afferent branches of the vagus nerve (X). The medulla, in turn, regulates breathing and blood pressure.
Disorders
A paraganglioma is a tumor that may involve the aortic body.
Swelling can also occur.
Nomenclature
Some sources equate the "aortic bodies" and "paraaortic bodies", while other sources explicitly distinguish between the two.[3][4] When a distinction is made, the "aortic bodies" are chemoreceptors which regulate Circulatory system, while the "paraaortic bodies" are the chromaffin cells which manufacture catecholamines.
References
- ^ 1409679417 at GPnotebook
- ^ [1]
- ^ Aortic+Bodies at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Para-Aortic+Bodies at the US National Library of Medicine Medical Subject Headings (MeSH)
See also
- Carotid body
- Control of respiration
- Peripheral chemoreceptors
Cardiovascular system, physiology: cardiovascular physiology
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Heart |
Volumes |
- Stroke volume = End-diastolic volume – End-systolic volume
- Cardiac output = Heart rate × Stroke volume
- Frank–Starling law of the heart
- Cardiac function curve
- Venous return curve
- Aortic valve area calculation
- Ejection fraction
- Cardiac index
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Dimensions |
- Fractional shortening = (End-diastolic dimension – End-systolic dimension) / End-diastolic dimension
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Interaction diagrams |
- Cardiac cycle
- Wiggers diagram
- Pressure volume diagram
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Tropism |
- Chronotropic (Heart rate)
- Dromotropic (Conduction velocity)
- Inotropic (Contractility)
- Bathmotropic (Excitability)
- Lusitropic (Relaxation)
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Conduction system /
Cardiac electrophysiology |
- Cardiac action potential
- Atrial action potential
- Ventricular action potential
- Effective refractory period
- Pacemaker potential
- EKG
- P wave
- PR interval
- QRS complex
- QT interval
- ST segment
- T wave
- U wave
- Hexaxial reference system
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Chamber pressure |
Central venous pressure/right atrial pressure → Right ventricular pressure → Pulmonary artery pressure → Pulmonary wedge pressure/left atrial pressure → Left ventricular pressure → Aortic pressure
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Other |
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Vascular system/
Hemodynamics |
Blood flow |
- Compliance
- Vascular resistance
- Total peripheral resistance
- Pulse
- Perfusion
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Blood pressure |
- Pulse pressure
- Mean arterial pressure
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Regulation of BP |
- Baroreflex
- Kinin–kallikrein system
- Renin–angiotensin system
- Vasoconstrictors/Vasodilators
- Autoregulation
- Myogenic mechanism
- Tubuloglomerular feedback
- Cerebral autoregulation
- Paraganglia
- Aortic body
- Carotid body
- Glomus cell
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noco/cong/tumr, sysi/epon, injr
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proc, drug (C1A/1B/1C/1D), blte
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anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot
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noco/syva/cong/lyvd/tumr, sysi/epon, injr
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proc, drug (C2s+n/3/4/5/7/8/9)
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List of arteries of torso · chest (TA A12.2.01–04,11, GA 6.598)
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Pulmonary |
- Right pulmonary artery
- Left pulmonary artery (Ligamentum arteriosum)
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Coronary |
- Right coronary: SA nodal
- AV nodal
- Atrial
- Right marginal
- Posterior interventricular
Left coronary: Anterior interventricular
- Left circumflex (Left marginal)
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Ascending aorta/
aortic arch |
Brachiocephalic
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- Thyreoidea ima
- Right subclavian
- Right common carotid
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Left common carotid
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- External carotid
- Internal carotid
- Carotid body
- Carotid sinus
- Carotid bifurcation
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Left subclavian
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- Internal thoracic: Anterior intercostal
- Thymic
- Pericardiacophrenic
- Perforating branches
- terminal (Musculophrenic, superior epigastric)
- Kacheshmarova's artery (Arteria xiphia (Arteria africana))
- Costocervical trunk: Highest intercostal (Posterior intercostal 1–2)
- Deep cervical
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Other
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Descending/
thoracic aorta |
- visceral: Bronchial
- Esophageal
- Mediastinal
- parietal: Posterior intercostal 3·11
- Subcostal
- Superior phrenic
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anat (a:h/u/t/a/l,v:h/u/t/a/l)/phys/devp/cell/prot
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noco/syva/cong/lyvd/tumr, sysi/epon, injr
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proc, drug (C2s+n/3/4/5/7/8/9)
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UpToDate Contents
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- 1. 換気調節 control of ventilation
- 2. 換気調節障害 disorders of ventilatory control
- 3. 頚部腫瘤の鑑別診断 differential diagnosis of a neck mass
- 4. 早産児における無呼吸の病因、臨床症状、および診断 pathogenesis clinical presentation and diagnosis of apnea of prematurity
- 5. 傍神経節腫:限局性疾患の治療 paragangliomas treatment of locoregional disease
English Journal
- Urocortin 2 is associated with abdominal aortic aneurysm and mediates anti-proliferative effects on vascular smooth muscle cells via corticotrophin releasing factor receptor 2.
- Emeto TI1, Moxon JV1, Biros E1, Rush CM, Clancy P1, Woodward L1, Moran CS1, Jose RJ1, Nguyen T1, Walker PJ, Golledge J.Author information 1*The Vascular Biology Unit, Queensland Research Centre for Peripheral Vascular Disease, School of Medicine and Dentistry, James Cook University, James Cook Drive, Douglas, Townsville, QLD 4811, Australia.AbstractAAA (abdominal aortic aneurysm) is an important cause of sudden death in older adults, but there is no current effective drug therapy for this disease. The UCNs (urocortins1-3) and their receptors: CRFR (corticotrophin-releasing factor receptor)-1 and -2 have been implicated in various CVDs (cardiovascular diseases). We assessed the relative expression of UCN1-3 in AAA by qRT-PCR (quantitative reverse transcription-PCR) and ELISA, and examined in vitro how UCN2 affects human aortic VSMC (vascular smooth muscle cell) Akt phosphorylation, pro-inflammatory cytokine IL (interleukin)-6 secretion, proliferation, cell cycle and apoptosis. UCN2 and CRFR2 expression were significantly up-regulated in biopsies from the AAA body. AAA body biopsies released high amounts of UCN2 in vitro. Median plasma UCN2 concentrations were 2.20 ng/ml (interquartile range 1.14-4.55 ng/ml, n=67) in AAA patients and 1.11 ng/ml (interquartile range 0.76-2.55 ng/ml, n=67) in patients with non-aneurysmal PAD (peripheral artery disease) (P=0.001). Patients with UCN2 in the highest quartile had a 4.12-fold (95% confidence interval, 1.37-12.40) greater prevalence of AAA independent of other risk factors, P=0.012. In vitro, UCN2 significantly inhibited VSMC Akt phosphorylation and proliferation in a dose-dependent manner. UCN2 induced VSMC G1 cell-cycle arrest and increased IL-6 secretion over 24 h. The CRFR2 antagonist astressin-2B significantly abrogated the effects of UCN2 on VSMCs. In conclusion, UCN2 is significantly associated with AAA and inhibits VSMC proliferation by inducing a G1 cell cycle arrest suggesting a plausible regulatory role in AAA pathogenesis.
- Clinical science (London, England : 1979).Clin Sci (Lond).2014 Apr;126(7):517-27. doi: 10.1042/CS20130425.
- AAA (abdominal aortic aneurysm) is an important cause of sudden death in older adults, but there is no current effective drug therapy for this disease. The UCNs (urocortins1-3) and their receptors: CRFR (corticotrophin-releasing factor receptor)-1 and -2 have been implicated in various CVDs (cardiov
- PMID 24107226
- Abdominal visceral and subcutaneous fat increase, insulin resistance and hyperlipidemia in testicular cancer patients treated with cisplatin-based chemotherapy.
- Willemse PP1, van der Meer RW, Burggraaf J, van Elderen SG, de Kam ML, de Roos A, Lamb HJ, Osanto S.Author information 1Department of Clinical Oncology, Leiden University Medical Center , Leiden , The Netherlands.AbstractAbstract Background. Testicular cancer survivors treated with chemotherapy are at increased risk for metabolic syndrome (MetS) and cardiovascular disease (CVD). We explored acute effects of chemotherapy by assessing metabolic factors, abdominal fat volume, hepatic triglyceride content (HTC) and aortic wall stiffness. Material and methods. We studied 19 testicular cancer patients (age 20-54 years) before, at three and nine months after the start of chemotherapy. Blood serum was analyzed for lipids, glucose and insulin. Abdominal visceral and subcutaneous fat volume and aortic pulse wave velocity were assessed by magnetic resonance imaging (MRI) techniques; HTC was measured by proton MR spectroscopy. Results. Three months after start of chemotherapy visceral abdominal fat volume had significantly increased from 202 ± 141 to 237 ± 153 ml (p = 0.009) whereas body mass index and subcutaneous fat volume significantly increased nine months after treatment from 24.4 ± 4.0 to 26.4 ± 4.1 kg/m(2) (p = 0.01) and from 556 ± 394 to 668 ± 460 ml (p = 0.002) respectively. Serum total cholesterol, low-density lipoprotein cholesterol and insulin also significantly increased three months after start of treatment from 4.88 ± 1.1 to 5.61 ± 1.50 mmol/l (p = 0.002), 3.31 ± 1.16 to 3.73 ± 1.41 mmol/l (p = 0.02) and 5.7 ± 4.4 to 9.6 ± 6.3 mU/ml (p = 0.03), respectively. Nine months after start of chemotherapy serum lipid and insulin concentrations had returned to baseline. HTC increased in seven of the 19 patients (36.8%) during follow-up. Aortic pulse wave velocity remained unchanged at the three time points measured. Conclusion. Cisplatin-based chemotherapy was associated with acute insulin resistance, dyslipidemia and an immediate increase in abdominal visceral adipose tissue and abdominal subcutaneous adipose tissue in testicular cancer patients. A large prospective cohort study with long follow-up is warranted to characterize the time course and relationship between acutely induced obesity and hypercholesterolemia and the development of metabolic syndrome and CVD years later in individual testicular cancer survivors.
- Acta oncologica (Stockholm, Sweden).Acta Oncol.2014 Mar;53(3):351-60. doi: 10.3109/0284186X.2013.819116. Epub 2013 Aug 19.
- Abstract Background. Testicular cancer survivors treated with chemotherapy are at increased risk for metabolic syndrome (MetS) and cardiovascular disease (CVD). We explored acute effects of chemotherapy by assessing metabolic factors, abdominal fat volume, hepatic triglyceride content (HTC) and aort
- PMID 23957624
Japanese Journal
- 2)センチネルリンパ節の同定,生検による微小転移の検索 : 確実なリンパ節郭清と治療の個別化(シンポジウム2「子宮体癌治療戦略の新展開」,第63回日本産科婦人科学会・学術講演会)
- 新倉 仁
- 日本産科婦人科學會雜誌 63(12), 2209-2218, 2011-12-01
- … The detection area of SLNs was limited to the pelvic area only: SLNs could not be identified around the para-aortic area. … Comparison between different detection techniques: The same SLNs were detected in 8 of 9 patients by hysteroscopic injection of RI compared with direct injection of blue dye into the uterine body. … The SLN detection area by cervical injection of RI included that detected by direct uterine body injection of blue dye in all 12 cases. …
- NAID 110008799040
- Pregnancy-Associated Aortic Dilatation or Dissection in Japanese Women With Marfan Syndrome
- KATSURAGI Shinji,UEDA Keiko,YAMANAKA Kaoru,NEKI Reiko,KAMIYA Chizuko,SASAKI Yoshihito,OSATO Kazuhiro,NIWA Koichiro,IKEDA Tomoaki
- Circulation journal : official journal of the Japanese Circulation Society 75(11), 2545-2551, 2011-10-25
- … Background: Aortic dilatation and dissection are severe complications of pregnancy that may cause maternal death. … The purpose of the present study was to investigate risk factors for aortic dilatation or dissection in pregnant Japanese women with Marfan syndrome. … These patients were divided into 2 groups: those who experienced aortic dilatation or dissection (group D, n=11) and those who did not (group ND, n=17). …
- NAID 10030031923
Related Links
- aortic body n. One of the small bilateral structures, attached to a small branch of the aorta near its arch, and containing chemoreceptors that respond primarily to decreases in blood oxygen concentration. aortic body, one of several ...
- aortic [a-or´tik] pertaining to the aorta. aortic arch syndrome any of a group of disorders adding to occlusion of the arteries arising from the aortic arch; such occlusion may be caused by atherosclerosis, arterial embolism, or other ...
Related Pictures
★リンクテーブル★
[★]
- 英
- chemoreceptor
- 同
- 化学受容体
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[★]
- 英
- aortic body
- ラ
- glomusa orticum
- 関
- 化学受容器
[★]
大動脈傍体
- 関
- organ of Zuckerkandl
[★]
- 関
- aorta、aortae、aortal
[★]