WordNet

(medicine) any disturbance in the functioning of an organ or body part or a disturbance in the functioning of a social group; "erectile dysfunction"; "sexual relationship dysfunction" (同)disfunction
relating to cells; "cellular walls"; "cellular physiology"
characterized by or divided into or containing cells or compartments (the smallest organizational or structural unit of an organism or organization); "the cellular construction of a beehive"; "any effective opposition to a totalitarian regime must be secretive and cellular"

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1. 拡張能障害の細胞学的機序 cellular mechanisms of diastolic dysfunction
2. HIV感染患者における心血管疾患の病因およびバイオマーカー pathogenesis and biomarkers of cardiovascular disease in hiv infected patients
3. 初期肺移植片機能不全 primary lung graft dysfunction
4. 無症候性左室機能不全に対するスクリーニング screening for asymptomatic left ventricular dysfunction
5. 小児における膀胱機能障害の病因および臨床的特徴 etiology and clinical features of bladder dysfunction in children

Effects of early hemodynamic resuscitation on left ventricular performance and microcirculatory function during endotoxic shock.

López A1, Grignola JC, Angulo M, Alvez I, Nin N, Lacuesta G, Baz M, Cardinal P, Prestes I, Bouchacourt JP, Riva J, Ince C, Hurtado FJ.
Intensive care medicine experimental.Intensive Care Med Exp.2015 Dec;3(1):49. doi: 10.1186/s40635-015-0049-y. Epub 2015 May 8.
BACKGROUND: Microcirculation and macrohemodynamics are severely compromised during septic shock. However, the relationship between these two compartments needs to be further investigated. We hypothesized that early resuscitation restores left ventricular (LV) performance and microcirculatory functio
PMID 26215813

Para-cresyl sulfate acutely impairs vascular reactivity and induces vascular remodeling.

Gross P1, Massy ZA1,2, Henaut L1, Boudot C1, Cagnard J1, March C1, Kamel S1, Drueke TB1, Six I1.
Journal of cellular physiology.J Cell Physiol.2015 Dec;230(12):2927-35. doi: 10.1002/jcp.25018.
Chronic kidney disease (CKD) is characterized by vascular remodeling and the retention of uremic toxins, several of which are independently associated with the high cardiovascular mortality rate in CKD patients. Whether the association between these uremic toxins and cardiovascular mortality is due
PMID 25899466

Anticancer activity studies of a ruthenium(II) polypyridyl complex against human hepatocellular (BEL-7402) cells.

Li W1, Han BJ1, Yao JH2, Jiang GB1, Lin GJ1, Xie YY1, Huang HL3, Liu YJ4.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.Spectrochim Acta A Mol Biomol Spectrosc.2015 Nov 5;150:127-34. doi: 10.1016/j.saa.2015.05.032. Epub 2015 May 25.
A Ru(II) polypyridyl complex [Ru(bpy)2(HMSPIP)](ClO4)2 (1) (bpy=2,2'-bipyridine, HMSPIP=2-(4-methylsulfonyl)phenyl-1H-imidazo[4,5-f][1,10] phenanthroline) was synthesized. The IC50 value of the complex against human hepatocellular cell BEL-7402 is 21.6±2.7μM. The complex shows no cytotoxic activit
PMID 26037497

A novel in-frame deletion in the leucine zipper domain of C/EBPε leads to neutrophil-specific granule deficiency

Wada Taizo,Akagi Tadayuki,Muraoka Masahiro,Toma Tomoko,Kaji Kenzo,Agematsu Kazunaga,Koeffler Phillip,Yokota Takashi,Yachie Akihiro
Journal of Immunology 195(1), 80-86, 2015-07-01
… Neutrophil-specific granule deficiency (SGD) is a rare autosomal recessive primary immunodeficiency characterized by neutrophil dysfunction, bilobed neutrophil nuclei and lack of neutrophil-specific granules. … Biochemical analysis revealed that, in contrast to the two frameshift mutations, the ΔRS mutant maintained normal cellular localization, DNA-binding activity, and dimerization, and all three mutants exhibited marked reduction in transcriptional activity. …
NAID 120005647665

OTANI SATORU
順天堂醫事雑誌 61(2), 171-174, 2015
… This type of memory is thought to be formed and stored in the prefrontal cortex, taking at the cellular level the form of synaptic plasticity. … Abnormal synaptic plasticity is also seen in the prefrontal cortex after injection of the psychoactive drug MK801, which is known to cause schizophrenia-like cognitive dysfunction in humans. …
NAID 130005093610

Curcumin Attenuates Hydrogen Peroxide-Induced Premature Senescence via the Activation of SIRT1 in Human Umbilical Vein Endothelial Cells

Sun Yueliu,Hu Xiaorong,Hu Gangying [他],Xu Changwu,Jiang Hong
Biological and Pharmaceutical Bulletin 38(8), 1134-1141, 2015
… Endothelial senescence has been proposed to be involved in endothelial dysfunction and atherogenesis. … Treatment with curcumin alone enhanced the enzymatic activity of SIRT1, but didn't affect cellular senescence, cell growth or apoptosis compared to the Control. …
NAID 130005090660