WordNet

relating to cells; "cellular walls"; "cellular physiology"
characterized by or divided into or containing cells or compartments (the smallest organizational or structural unit of an organism or organization); "the cellular construction of a beehive"; "any effective opposition to a totalitarian regime must be secretive and cellular"
the state of having cells
an immune response (chiefly against viral or fungal invasions or transplanted tissue) that involves T cells
small room in which a monk or nun lives (同)cubicle
a device that delivers an electric current as the result of a chemical reaction (同)electric cell
a room where a prisoner is kept (同)jail cell, prison cell
(biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
any small compartment; "the cells of a honeycomb"
a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
occupy an intermediate or middle position or form a connecting link or stage between two others; "mediate between the old and the new"
acting through or dependent on an intervening agency; "the disease spread by mediate as well as direct contact"
acting or brought about through an intervening agency; "the mediated settlement brought satisfaction to both sides"

PrepTutorEJDIC

(刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
〈紛争・相違点など〉‘を'調停する,仲裁する / 〈妥協・和解・同意など〉‘を'仲裁して成立させる / (両者の)調停をする《+『between』+『名』》 / 仲介者(媒介物)を通じての,間接の

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/12/16 02:45:50」(JST)

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[Wiki en表示]

Cell-mediated immunity is an immune response that does not involve antibodies, but rather involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in response to an antigen.

Historically, the immune system was separated into two branches: humoral immunity, for which the protective function of immunization could be found in the humor (cell-free bodily fluid or serum) and cellular immunity, for which the protective function of immunization was associated with cells. CD4 cells or helper T cells provide protection against different pathogens. Cytotoxic T cells cause death by apoptosis without using cytokines; therefore in cell-mediated immunity cytokines are not always present.

The innate immune system and the adaptive immune system each comprise both humoral and cell-mediated components.

Cellular immunity protects the body by:

T-cell mediated immunity or T-cell immunity : activating antigen-specific cytotoxic T cells that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;
activating macrophages and natural killer cells, enabling them to destroy pathogens; and
stimulating cells^{[clarification needed]} to secrete a variety^{[clarification needed]} of cytokines that influence the function of other cells^{[clarification needed]} involved in adaptive immune responses and innate immune responses.^{[citation needed]}

Cell-mediated immunity is directed primarily at microbes that survive in phagocytes and microbes that infect non-phagocytic cells. It is most effective in removing virus-infected cells, but also participates in defending against fungi, protozoans, cancers, and intracellular bacteria. It also plays a major role in transplant rejection.

References

Cell-mediated immunity (Encyclopædia Britannica)
Chapter 8:T Cell-Mediated Immunity Immunobiology: The Immune System in Health and Disease. 5th edition.

UpToDate Contents

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1. T細胞受容体シグナル伝達 t cell receptor signaling
2. NK細胞欠損症候群：臨床症状および診断 nk cell deficiency syndromes clinical manifestations and diagnosis
3. Treatment of acute T cell-mediated (cellular) rejection of the renal allograft
4. 適応細胞性免疫応答 the adaptive cellular immune response
5. HLAハプロタイプ適合造血細胞移植 hla haploidentical hematopoietic cell transplantation

English Journal

Antioxidant, anti-inflammatory and anti-septic potential of phenolic acids and flavonoid fractions isolated from Lolium multiflorum.

Choi KC1, Son YO2, Hwang JM3, Kim BT3, Chae M3, Lee JC3,4.
Pharmaceutical biology.Pharm Biol.2017 Dec;55(1):611-619.
CONTEXT: Interest has recently renewed in using Lolium multiflorum Lam. (Poaceae) (called Italian ryegrass; IRG) silage as an antioxidant and anti-inflammatory diet.OBJECTIVE: This study investigated the antioxidant, anti-inflammatory and anti-septic potential of IRG silage and identified the primar
PMID 27937124

Hydrolysis of Hyaluronic Acid in Lymphedematous Tissue Alleviates Fibrogenesis via TH1 Cell-Mediated Cytokine Expression.

Cho S1, Roh K1, Park J1, Park YS1, Lee M1, Cho S1, Kil EJ1, Cho MJ1, Oh JS1, Byun HS1, Cho SH1, Park K2, Kang H3, Koo J4, Yeom CH5, Lee S6.
Scientific reports.Sci Rep.2017 Dec;7(1):35. doi: 10.1038/s41598-017-00085-z. Epub 2017 Feb 24.
Although surgery and radiation are beneficial for treating cancer, they can also lead to malfunctions of the lymphatic system such as secondary lymphedema. This abnormality of the lymphatic system is characterized by severe swelling, adipogenesis, inflammation, and fibrosis in the lymphedematous reg
PMID 28232732

A novel strategy to achieve effective drug delivery: exploit cells as carrier combined with nanoparticles.

Pang L1, Zhang C1, Qin J1, Han L1, Li R1, Hong C1, He H2, Wang J1.
Drug delivery.Drug Deliv.2017 Nov;24(1):83-91. doi: 10.1080/10717544.2016.1230903.
Cell-mediated drug delivery systems employ specific cells as drug vehicles to deliver drugs to targeted sites. Therapeutics or imaging agents are loaded into these cells and then released in diseased sites. These specific cells mainly include red blood cells, leukocytes, stem cells and so on. The ce
PMID 28155538

Japanese Journal

NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs

Stem Cell
NAID 120006343758

自己免疫疾患治療剤発明の共同出願を単独分割出願したことに対してなされた不服審判の判例分析 : 米国ダートマス大学単独分割出願特許審判事件「decision J2/01 (Teilanmeldung/THE TRUSTEES OF DARTMOUTH COLLEGE) of 4.2.2004」

青山社会科学紀要 45(2), 67-105, 2017-03
NAID 120006239412

ATLに対するmogamulizumab併用遺伝子修飾T細胞療法の可能性 (特集血液腫瘍に対する免疫療法の新たな展開)

血液内科 = Hematology 74(1), 51-57, 2017-01
NAID 40021065521

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★リンクテーブル★

リンク元	「cellular」「細胞性」「cellularity」
拡張検索	「antibody-dependent cell-mediated cytotoxicity」
関連記事	「mediate」「cell」