WordNet
- the 14th letter of the Roman alphabet (同)n
PrepTutorEJDIC
- nitrogenの化学記号
- neodymiumの化学記号
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2018/02/09 22:01:40」(JST)
wiki en
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 尿路上皮（移行上皮）膀胱癌の疫学および危険因子epidemiology and risk factors of urothelial transitional cell carcinoma of the bladder [show details]
- 2. 薬物誘発性ループスdrug induced lupus [show details]
- 3. イソニアジド肝毒性isoniazid hepatotoxicity [show details]
- 4. メラトニンの生理学および臨床使用physiology and available preparations of melatonin [show details]
- 5. 職業性喘息：定義、疫学、原因、および危険因子occupational asthma definitions epidemiology causes and risk factors [show details]
English Journal
- Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice.
- Wang S1, Bott D1, Tung A1, Sugamori KS1, Grant DM2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Jul;43(7):916-21. doi: 10.1124/dmd.115.063297. Epub 2015 Apr 28.
- 4-Aminobiphenyl (ABP), a prototypical aromatic amine carcinogen in rodents and humans, requires bioactivation to manifest its toxic effects. A traditional model of ABP bioactivation, based on in vitro enzyme kinetic evidence, had postulated initial N-hydroxylation by the cytochrome P450 isoform CYP1
- PMID 25922528
- Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652.
- Rioux N1, Mitchell LH1, Tiller P1, Plant K1, Shaw J1, Frost K1, Ribich S1, Moyer MP1, Copeland RA1, Chesworth R1, Waters NJ2.
- Drug metabolism and disposition: the biological fate of chemicals.Drug Metab Dispos.2015 Jul;43(7):936-43. doi: 10.1124/dmd.115.064014. Epub 2015 Apr 17.
- Pharmacokinetic and metabolite identification studies were conducted to understand the clearance pathways of EPZ011652 [(2-aminoethyl)(methyl)({3-[4-(propan-2-yloxy)phenyl]-1H-pyrazol-4-yl}methyl)amine], a potent protein arginine N-methyltransferase inhibitor. Metabolic clearance was the major pathw
- PMID 25887455
- Transgenic maize event TC1507: global status of food, feed, and environmental safety.
- Baktavachalam GB1, Delaney B, Fisher TL, Ladics GS, Layton RJ, Locke ME, Schmidt J, Anderson JA, Weber NN, Herman RA, Evans SL.
- GM crops & food.GM Crops Food.2015 May 27:0. [Epub ahead of print]
- Maize (Zea mays) is a widely cultivated cereal that has been safely consumed by humans and animals for centuries. Transgenic or genetically engineered insect-resistant and herbicide tolerant maize, are commercially grown on a broad scale. Event TC1507 (OECD unique identifier: DAS-Ø15Ø 7-1) or the
- PMID 26018138
Japanese Journal
- 4Dp10 Microbial production of N-acetyl cis-4-hydroxy-L-proline by coexpression of the Rhizobium L-proline cis-4-hydroxylase and the yeast N-acetyltranferase Mpr1
- Hoa Bach Thi Mai,Hara Ryotaro,Kino Kuniki,Takagi Hiroshi
- 日本生物工学会大会講演要旨集 64, 207, 2012-09-25
- NAID 110009609971
- Production of N-acetyl cis-4-hydroxy-L-proline by the yeast N-acetyltransferase Mpr1
- HOA Bach Thi Mai,HIBI Takao,NASUNO Ryo,MATSUO Goh,SASANO Yu,TAKAGI Hiroshi
- Journal of bioscience and bioengineering 114(2), 160-165, 2012-08-25
- NAID 10031132194
- Production of N-acetyl cis-4-hydroxy-L-proline by the yeast N-acetyltransferase Mpr1(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Hoa Bach Thi Mai,Hibi Takao,Nasuno Ryo [他],Matsuo Goh,Sasano Yu,Takagi Hiroshi
- Journal of bioscience and bioengineering 114(2), 160-165, 2012-08
- … To promote retention in blood or decrease toxicity, N-acetylation of CHOP might be a novel approach as a prodrug, instead of other approaches such as the conjugation of poly(ethylene glycol-Lys) or the modification of O-acetylation. … In this study, we found that N-acetyltransferase Mpr1 that detoxifies the proline analog azetidine-2-carboxylate in Saccharomyces cerevisiae also converts CHOP into N-acetyl CHOP in vitro and in vivo. …
- NAID 110009495422
Related Links
- Ebook Download Search E.g: English grammar, Ethical hacking N-acetyltransferase 2 PDF N-acetyltransferase 2: Slow, intermediate or fast? A Book Size: 1.91 MB | Pdf Pages: 102 222 G. D. Pietro . et al. / Open ...
- This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which ...
Related Pictures
★リンクテーブル★
「薬物代謝」
- 英
- drug metabolism
- 関
- 肝臓が貢献。例外的に肺や腎で代謝されることもある
薬物代謝の過程
1. 第1相反応：酸化oxidation、還元reduction、加水分解hydrolysis
- oxygenases
- -OH, -COOH, SH, -O=, -NH2を付与
- 生物学的性質の不活化
2. 第2相反応：抱合conjugation
- transerases
- 可溶化。分子量の増加→腎排泄されやすくなる
生物異物代謝 (GOO.73)
| ENZYMES | 反応 | ||||
| Phase 1 | oxygenases | シトクロムP450 | cytochrome P450 | CYP | C, Oの酸化。脱アルキル化 |
| フラビン含有モノオキシゲナーゼ | flavin-containing monooxygenase | FMO | N,S,Pの酸化 | ||
| エポキシドヒドラーゼ(mEH, sEH) | epoxide hydrolases | mEH, sEH | エポキシドの加水分解 | ||
| Phase 2 | transferases? | スルホトランスフェラーゼ | sulfotransferase | SULT | 硫酸の |
| UDP-グルクロノシルトランスフェラーゼ | UDP-glucuronosyltransferase | UGT | グルクロン酸の付加 | ||
| グルタチオンS-トランスフェラーゼ | glutathione-S-transferase | GST | グルタチオンの付加 | ||
| N-アセチルトランスフェラーゼ | N-acetyltransferase | NAT | アセチル基の付加 | ||
| メチルトランスフェラーゼ | methyltransferase | MT | メチル基の付加 | ||
| Other enzymes? | アルコール脱水素酵素 | alcohol dehydrogenases | ADH | アルコールの還元 | |
| アルデヒド脱水素酵素 | aldehyde dehydrogenases | ALDH | アルデヒドの還元 | ||
| NADPH/キノン酸化還元酵素 | NADPH-quinone oxidoreductase | NQO | キノンの還元 | ||
「N-アセチル基転移酵素」
「N-アセチルトランスフェラーゼ」
「glucosamine 6-phosphate N-acetyltransferase」
グルコサミン-6-リン酸-N-アセチル基転移酵素、グルコサミン-6-リン酸-N-アセチルトランスフェラーゼ
「arylalkylamine N-acetyltransferase」
- 関
- AANAT
「arylamine N-acetyltransferase」
「amino-acid N-acetyltransferase」
「acetyltransferase」
アセチルトランスフェラーゼ、アセチル基転移酵素、アセチル化酵素
「n」
- n.
- pの前の[n]はmと記載する。synptom→symptom
「N」
- アスパラギン asparagine
- 窒素(原子、分子)