PrepTutorEJDIC
- 〈U〉〈C〉(…の)(量・額などの)不足,欠乏《+『of』(『in』)+『名』》 / 〈C〉不足分,不足量,不足額 / 〈C〉(精神・肉体などの)欠陥
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. Toll様受容体：疾患および治療における役割 toll like receptors roles in disease and therapy
- 2. 複合免疫不全 combined immunodeficiencies
English Journal
- Invasive Bacterial Infection in Patients with Interleukin-1 Receptor-associated Kinase 4 Deficiency: Case Report.
- Takada H1, Ishimura M, Takimoto T, Kohagura T, Yoshikawa H, Imaizumi M, Shichijyou K, Shimabukuro Y, Kise T, Hyakuna N, Ohara O, Nonoyama S, Hara T.
- Medicine.Medicine (Baltimore).2016 Jan;95(4):e2437. doi: 10.1097/MD.0000000000002437.
- Interleukin-1 receptor-associated kinase 4 (IRAK4) deficiency (OMIM #607676) is a rare primary immunodeficiency of innate immune defect. We identified 10 patients from 6 families with IRAK4 deficiency in Japan, and analyzed the clinical characteristics of this disease.Nine patients had homozygous c.
- PMID 26825884
- Deficiency of interleukin-1 receptor-associated kinase 4 presenting as fatal Pseudomonas aeruginosa bacteremia in two siblings.
- Stergiopoulou T1, Walsh TJ, Seghaye MC, Netea MG, Casanova JL, Moutschen M, Picard C.
- The Pediatric infectious disease journal.Pediatr Infect Dis J.2015 Mar;34(3):299-300. doi: 10.1097/INF.0000000000000550.
- Interleukin-1 receptor-associated kinase 4 (IRAK-4) deficiency is a primary immunodeficiency of innate immunity. This is the case of a previous healthy toddler and his sibling, who both died of fulminant sepsis due to Pseudomonas aeruginosa. Subsequent genetic analysis demonstrated IRAK-4 deficiency
- PMID 25232776
- Interleukin-1 receptor-associated kinase-4 (IRAK4) promotes inflammatory osteolysis by activating osteoclasts and inhibiting formation of foreign body giant cells.
- Katsuyama E1, Miyamoto H1, Kobayashi T2, Sato Y3, Hao W1, Kanagawa H1, Fujie A1, Tando T1, Watanabe R1, Morita M4, Miyamoto K1, Niki Y1, Morioka H1, Matsumoto M1, Toyama Y1, Miyamoto T5.
- The Journal of biological chemistry.J Biol Chem.2015 Jan 9;290(2):716-26. doi: 10.1074/jbc.M114.568360. Epub 2014 Nov 17.
- Formation of foreign body giant cells (FBGCs) occurs following implantation of medical devices such as artificial joints and is implicated in implant failure associated with inflammation or microbial infection. Two major macrophage subpopulations, M1 and M2, play different roles in inflammation and
- PMID 25404736
Japanese Journal
- IRAK4欠損症と感染症
- 高田 英俊
- 小児感染免疫 23(1), 81-87, 2011-04-01
- NAID 10028185700
- 自然免疫異常による免疫不全症 (ミニ特集 ここまで分かっている免疫不全症候群)
- 高田 英俊,原 寿郎
- 小児科臨床 61(9), 1783-1789, 2008-09
- NAID 40016195232
- 本邦初の Interleukin-1 receptor associated kinase 4 欠損症兄弟例の臨床的特徴
- 吉川 秀人,北村 太郎,渡邊 周永,虻川 大樹,稲垣 徹史,武山 淳二,今泉 益栄,高田 英俊,原 寿郎
- 日本小児科学会雑誌 111(6), 750-754, 2007-06-01
- NAID 10019547650
Related Links
- IRAK-4 deficiency is caused by mutations in the IRAK4 gene, which provides instructions for making a protein that plays an important role in stimulating the immune system to respond to infection. The IRAK-4 protein is ...
- Individuals with IRAK-4 deficiency are at increased risk of developing infections by bacteria such as Str. penumoniae, Staph. aureus, and P. aeruginosa. Most people with IRAK-4 deficiency start to develop infections by age 2. The ...
Related Pictures
★リンクテーブル★
| 関連記事 | 「deficiency」「IRAK」「IRAK4」 |
「deficiency」
- n.
- 不足、欠乏、欠失、欠如、欠損、不十分。栄養不足、栄養素欠乏、欠乏症。(遺伝子)(染色体内の)遺伝子欠失
- 欠けているもの、不足している物。不足分。不完全なもの、欠点のあるもの
- 関
- absence, agenesis, dearth, defect, defective, deficient, deficit, delete, deletion, deletional, depletion, deprivation, deprive, lack, miss, missing, morphological defect, paucity, scarce, scarcity, starve