WordNet
- any physical damage to the body caused by violence or accident or fracture etc. (同)hurt, harm, trauma
- an act that causes someone or something to receive physical damage
- wrongdoing that violates anothers rights and is unjustly inflicted
- an accident that results in physical damage or hurt (同)accidental injury
- the 4th letter of the Roman alphabet (同)d
PrepTutorEJDIC
- 『負傷』,『損害』,損傷 / (名誉などを)傷つけること,侮辱《+『to』+『名』》
- deuteriumの化学記号
- deoxyribonucleic acidディオキシリボ核酸
UpToDate Contents
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- 1. 免疫抑制療法に関連したB型肝炎ウイルス再活性化 hepatitis b virus reactivation associated with immunosuppressive therapy
- 2. B型肝炎のマネージメントの概要および症例 overview of the management of hepatitis b and case examples
- 3. 小児および思春期におけるB型肝炎ウイルス感染の概要 overview of hepatitis b virus infection in children and adolescents
- 4. アテローム性動脈硬化症の病因 pathogenesis of atherosclerosis
- 5. アポトーシスと自己免疫疾患 apoptosis and autoimmune disease
English Journal
- Appraisal of antioxidant, anti-hemolytic and DNA shielding potentialities of chitosaccharides produced innovatively from shrimp shell by sequential treatment with immobilized enzymes.
- Halder SK1, Jana A1, Das A1, Paul T1, Das Mohapatra PK1, Pati BR1, Mondal KC2.Author information 1Department of Microbiology, Vidyasagar University, West Bengal 721102, India.2Department of Microbiology, Vidyasagar University, West Bengal 721102, India. Electronic address: mondalkc@gmail.com.AbstractChitosaccharides (CS) of varied size were prepared from shrimp shell through sequential catalysis, using crude protease and chitinase enzymes immobilized on agar beads. In the optimized state, immobilization yield and activity yield for protease were 84% and 62%, and for chitinase were 75% and 57%, respectively. Immobilized protease and chitinase treatment improved CS yields (101μg/ml) and retained 63% and 52% of activities after 10 reuses, respectively. Stronger radical-scavenging activity (RSA) of CS against ABTS, DPPH and hydroxyl radical was noted with EC50 values 19.1, 26.4 and 29.6μg/ml, respectively. Peroxyl and superoxide RSAs of 96.8% and 88.6% were noticed at 70μg/ml of CS. Singlet oxygen quenching, reducing power and ferrous ion-chelating activities of CS were also pronounced. CS reasonably reduced oxidative damage of DNA, protein and RBC by inhibiting H2O2 and AAPH radicals. Reversible CS-DNA condensation leads to DNA stabilization without changing its conformation and advocates its employment in gene therapy.
- Food chemistry.Food Chem.2014 Sep 1;158:325-34. doi: 10.1016/j.foodchem.2014.02.115. Epub 2014 Mar 1.
- Chitosaccharides (CS) of varied size were prepared from shrimp shell through sequential catalysis, using crude protease and chitinase enzymes immobilized on agar beads. In the optimized state, immobilization yield and activity yield for protease were 84% and 62%, and for chitinase were 75% and 57%,
- PMID 24731350
- Antioxidant activity and characterization of antioxidant polysaccharides from pine needle (Cedrus deodara).
- Zeng WC1, Zhang Z2, Jia LR3.Author information 1College of Light Industry, Textile and Food Engineering, Sichuan University, Chengdu 610065, PR China.2College of Life Sciences, Sichuan University, Chengdu 610065, PR China.3College of Light Industry, Textile and Food Engineering, Sichuan University, Chengdu 610065, PR China. Electronic address: lrjia@sina.com.AbstractA novel antioxidant polysaccharide (APC) was isolated and characterized from pine needles of Cedrus deodara with the evaluation of its in vitro antioxidant activity. According to gel filtration chromatography, high performance size exclusion chromatography, gas chromatography-mass spectrometry, partial acid hydrolysis, periodic acid oxidation, Smith degradation and methylation analysis, APC was observed to be an acidic heteropolysaccharide (composed of glucose, arabinose, mannose and xylose in a molar ratio of 45.84:1:2.35:1.73) with the molecular weight of 1.53×10(4)Da, and the backbone was mainly composed by glucose, mannose and xylose in the form of (1→4) linked. Meanwhile, APC exhibited the remarkable antioxidant activity to scavenge free radicals and inhibit the oxidative injury of DNA and cells. The present results suggested that APC could be a potential antioxidant agent for preparing functional foods and nutraceuticals applied in food and pharmaceutical industries.
- Carbohydrate polymers.Carbohydr Polym.2014 Aug 8;108:58-64. doi: 10.1016/j.carbpol.2014.03.022. Epub 2014 Mar 22.
- A novel antioxidant polysaccharide (APC) was isolated and characterized from pine needles of Cedrus deodara with the evaluation of its in vitro antioxidant activity. According to gel filtration chromatography, high performance size exclusion chromatography, gas chromatography-mass spectrometry, part
- PMID 24751247
- Strawberry intake increases blood fluid, erythrocyte and mononuclear cell defenses against oxidative challenge.
- Tulipani S1, Armeni T1, Giampieri F1, Alvarez-Suarez JM1, Gonzalez-Paramás AM2, Santos-Buelga C2, Busco F3, Principato G1, Bompadre S4, Quiles JL5, Mezzetti B6, Battino M7.Author information 1Dipartimento di Science Cliniche Specialistiche ed Odontostomatologiche, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy.2Grupo de Investigación en Polifenoles (GIP-USAL), Faculty of Pharmacy, Salamanca University, Campus Miguel de Unamuno, E-37007 Salamanca, Spain.3Laboratory of Torrette-Umberto I Regional Hospital, Ancona, Italy.4Dipartimento di Scienze Biomediche e Sanità Pubblica, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy.5Instituto de Nutricion y Tecnologia de Alimentos (INYTA), Department of Physiology, Universidad de Granada, Granada, Spain.6Dipartimento di Scienze Agrarie, Alimentari ed Ambientali (D3A), Università Politecnica delle Marche, Ancona, Italy.7Dipartimento di Science Cliniche Specialistiche ed Odontostomatologiche, Facoltà di Medicina, Università Politecnica delle Marche, Ancona, Italy. Electronic address: m.a.battino@univpm.it.AbstractThe health promoting effects of a regular consumption of strawberries deserve attention, and a direct or indirect antioxidant role of strawberry bioactive compounds is among the most probable mechanisms underlying their beneficial properties. In the present study, we evaluated the overall effects of a 2-week daily consumption of strawberries on plasma antioxidant status, membrane lipid susceptibility to ex vivo-induced oxidation, and erythrocyte and mononuclear cell resistance to oxidative damage in apparently healthy volunteers. After strawberry intake, a moderate increase in fasting plasma antioxidant capacity and vitamin C was observed, together with a significant increase in the lag phase preceding plasma lipid oxidation. A significantly enhanced resistance to oxidative hemolysis was confirmed in red blood cells, while no significant changes were found in the extent of their membrane lipid peroxidation. For the first time, increased intake of strawberries for only 2weeks was shown to be sufficient to attenuate mononuclear cell mortality after ex vivo exposure to a single acuteoxidative challenge, but the analysis of DNA oxidative damage gave conflicting results. These findings suggest that a regular consumption of strawberries may enhance body defences against oxidative challenges.
- Food chemistry.Food Chem.2014 Aug 1;156:87-93. doi: 10.1016/j.foodchem.2014.01.098. Epub 2014 Feb 6.
- The health promoting effects of a regular consumption of strawberries deserve attention, and a direct or indirect antioxidant role of strawberry bioactive compounds is among the most probable mechanisms underlying their beneficial properties. In the present study, we evaluated the overall effects of
- PMID 24629942
Japanese Journal
- Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury.
- Nakagawa Shunsaku,Nishihara Kumiko,Inui Ken-Ichi,Masuda Satohiro
- European journal of pharmacology 696(1-3), 143-154, 2012-12-05
- … Simultaneously, increased signals for kidney injury molecule-1 and single-stranded DNA and decreased signals for Ki-67 in the proximal tubules were observed after treatment with everolimus, indicating that everolimus diminished renal function after acute tubular injury. …
- NAID 120004996384
- miR-196a Downregulation Increases the Expression of Type I and III Collagens in Keloid Fibroblasts
- Kashiyama Kazuya,Mitsutake Norisato,Matsuse Michiko,Ogi Tomoo,Saenko Vladimir A,Ujifuku Kenta,Utani Atsushi,Hirano Akiyoshi,Yamashita Shunichi
- Journal of Investigative Dermatology 132(6), 1597-1604, 2012-06
- … Keloids are a fibroproliferative disease due to abnormal wound healing process after skin injury. …
- NAID 120004664339
- Molecular nature of radiation injury and DNA repair disorders associated with radiosensitivity
- MASUDA Yuji,KAMIYA Kenji
- International journal of hematology 95(3), 239-245, 2012-03-01
- NAID 10030551664
Related Links
- DNA Injury (n.) 1. (MeSH) Injuries to DNA that introduce deviations from its normal, intact structure and which may, if left unrepaired, result in a MUTATION or a block of DNA REPLICATION. These deviations may be caused by ...
- Overview—DNA Damage and Repair and CNS Injury An overview of the mechanisms of DNA damage 1 2 3 and experimental evidence for DNA-related damage from studies of apoptosis in neuronal cultures and experimental ...
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★リンクテーブル★
| リンク元 | 「DNA損傷」「DNA傷害」「DNA lesion」「genotoxic stress」 |
| 関連記事 | 「injury」「D」「DNA」 |
「DNA損傷」
「DNA傷害」
「DNA lesion」
「genotoxic stress」
「injury」
- n.
「D」
- アスパラギン酸
- ジヒドロウリジン
- 遠位の distal,
- うつ病 depression
- 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)
「DNA」
- 英
- deoxyribonucleic acid
- 同
- デオキシリボ核酸
- 関
- リボ核酸 RNA