- 関
- DNA damage、DNA injury
WordNet
- to stress, single out as important; "Dr. Jones emphasizes exercise in addition to a change in diet" (同)emphasize, emphasise, punctuate, accent, accentuate
- special emphasis attached to something; "the stress was more on accuracy than on speed" (同)focus
- difficulty that causes worry or emotional tension; "she endured the stresses and strains of life"; "he presided over the economy during the period of the greatest stress and danger"- R.J.Samuelson (同)strain
- (physics) force that produces strain on a physical body; "the intensity of stress is expressed in units of force divided by units of area"
- the relative prominence of a syllable or musical note (especially with regard to stress or pitch); "he put the stress on the wrong syllable" (同)emphasis, accent
- put stress on; utter with an accent; "In Farsi, you accent the last syllable of each word" (同)accent, accentuate
- suffering severe physical strain or distress; "he dropped out of the race, clearly distressed and having difficulty breathing" (同)distressed
- bearing a stress or accent; "an iambic foot consists of an unstressed syllable followed by a stressed syllable as in `delay" (同)accented
PrepTutorEJDIC
- 〈U〉〈C〉(精神的・感情的な)『緊張』,ストレス / 〈U〉(…に対する)『強調』,力説《+on+名》 / 〈C〉〈U〉『強勢』,アクセント / 〈U〉(一般に)『圧迫』,圧力 / …‘を'『強調する』,力説する / 〈音節・語〉‘に'強勢(アクセント)を置く / 《まれ》(に)圧力をかける
UpToDate Contents
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English Journal
- Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors.
- Gaur S, Chen L, Yang L, Wu X, Un F, Yen Y.SourceDepartment of Molecular Pharmacology, Beckman Research Institute of the City of Hope, Duarte, CA 91010, United States.
- Cancer letters.Cancer Lett.2011 Dec 1;311(1):20-8. Epub 2011 Jun 29.
- The present study was performed to investigate the possible role of mTOR inhibitors in restoring chemosensitivity to adriamycin/cisplatin and elucidate the underlying mechanism. Combining adriamycin/cisplatin with torisel synergistically inhibited the cell proliferation in human oropharyngeal carcin
- PMID 21764510
- A spectrophotometric assay for conjugation of ubiquitin and ubiquitin-like proteins.
- Berndsen CE, Wolberger C.SourceDepartment of Biophysics and Biophysical Chemistry, Howard Hughes Medical Institute and the Johns Hopkins University School of Medicine, Baltimore, MD 21202, USA.
- Analytical biochemistry.Anal Biochem.2011 Nov 1;418(1):102-10. Epub 2011 Jul 2.
- Ubiquitination is a widely studied regulatory modification involved in protein degradation, DNA damage repair, and the immune response. Ubiquitin is conjugated to a substrate lysine in an enzymatic cascade involving an E1 ubiquitin-activating enzyme, an E2 ubiquitin-conjugating enzyme, and an E3 ubi
- PMID 21771579
Japanese Journal
- FoxO1 is involved in the antineoplastic effect of calorie restriction.
- Yamaza Haruyoshi,Komatsu Toshimitsu,Wakita Saori,Kijogi Carole,Park Seongjoon,Hayashi Hiroko,Chiba Takuya,Mori Ryoichi,Furuyama Tatsuo,Mori Nozomu,Shimokawa Isao
- Aging cell 9(3), 372-382, 2010-06
- … The response to oxidative stress, induced by intraperitoneal injection of 3-nitropropionic acid (3-NPA), was evaluated in the liver and hippocampus at 6 months of age. … Several of the selected FoxO1-target genes for cell cycle arrest, DNA repair, apoptosis, and stress resistance were up-regulated in the WT-CR tissues after 3-NPA injection, while the effect was mostly diminished in the HT-CR tissues. …
- NAID 120003203417
- Dual Mode of Regulation of Cell Division Cycle 25 A Protein by TRB3
- Sakai Satoshi,Ohoka Nobumichi,Onozaki Kikuo,Kitagawa Masatoshi,Nakanishi Makoto,Hayashi Hidetoshi
- Biological & Pharmaceutical Bulletin 33(7), 1112-1116, 2010
- … We have recently demonstrated that TRB3, a novel stress-inducible protein, is an unstable protein regulated by the ubiquitin-proteasome system. … Expression level of the endogenous TRB3 protein is down-regulated in a genotoxic condition. … These results suggest TRB3 is a regulator for adjusting the expression level of Cdc25A both in a normal and a genotoxic conditions. …
- NAID 130000300272
Related Links
- [edit] English. [edit] Noun. genotoxic stress (plural genotoxic stresses). Damage to the genome of an organism as the result of a genotoxin. Retrieved from "http:// en.wiktionary.org/wiki/genotoxic_stress". Category: English nouns ...
Related Pictures
★リンクテーブル★
[★]
- 関
- DNA damage、DNA lesion、genotoxic stress
[★]
- 英
- genotoxic stress
- 関
- DNA損傷
[★]
- 関
- accent、accentuate、accentuation、emphasis、emphasize、highlight、power point、strain、tone、tonus、underscore
[★]
- 関
- genetic toxicity、genotoxicity