英: death domain receptor signaling adaptor protein

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1. 複合免疫不全combined immunodeficiencies [show details]
… play roles in signal transduction by inflammatory cytokine receptors (eg, interleukin [IL] 1 and IL-18), as well as in pathways leading to programmed cell death (apoptosis) .… 3/gamma) deficiencies Caspase recruitment domain-containing protein 11 (CARD11) deficiency Mucosa-associated lymphoid…
2. ペプチドホルモンのシグナル伝達および調節peptide hormone signal transduction and regulation [show details]
… they can stimulate signaling pathways independent of G protein activation . Some peptides signal through receptors that are not linked to G proteins but instead are coupled… representative of these receptors possesses intrinsic protein tyrosine kinase activity. These receptors are comprised of an extracellular domain that is usually glycosylated, a single transmembrane domain,…
3. インスリン受容体の構造および機能structure and function of the insulin receptor [show details]
… residues in the receptor and downstream mediators via signaling domains in the effector proteins that specifically attach to the phosphorylated receptor tyrosines (eg, src homology [SH2] domains) . In contrast …
4. 肥満細胞：表面受容体とシグナル伝達mast cells surface receptors and signal transduction [show details]
… complement proteins, cytokine receptors (eg, for the alarmins interleukin-33 [IL-33] and thymic stromal lymphopoietin [TSLP]), neuropeptides, and opioids. A G-coupled protein receptor that is important… moment and acting on different receptors. This topic review will discuss the activating and inhibitory receptors on mast cells and signal transduction mechanisms.… SH2 domain with the phosphorylated ITAM on the gamma subunit of Fc-epsilon-RI . Syk then stimulates sequences leading to the mitogen-activated protein kinase (MAPK) pathways and the protein kinase…
5. T細胞受容体シグナル伝達t cell receptor signaling [show details]
… promoting the interaction of a number of signal transducing proteins including the adaptor Grb2-related adaptor protein-2 (GRAP2/Gads),… rings each containing specific receptors and signaling proteins. As examples, the TCR/CD3 complex and associated signaling proteins cluster into a "central supramolecular… cells (LAT) and Src-homology 2 domain-containing 76-kDa leukocyte protein (SLP-76). Further signaling proteins are then recruited,…

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★リンクテーブル★

リンク元	「death domain receptor signaling adaptor protein」
関連記事	「受容体」「デスドメイン」「受容」「体」「デスドメイン受容体」

「death domain receptor signaling adaptor protein」

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デスドメイン受容体シグナルアダプタータンパク質

「受容体」

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英: receptor
同: レセプター、リセプター
関

図：GOO.27

種類

イオンチャネル連結型受容体 (イオンチャネル型受容体)
酵素連結型受容体
Gタンパク質共役型受容体 (代謝調節型受容体)

First Aid FOR THE USMLE STEP 1 2006 p.199

一般的作動薬	受容体	G protein subunit	作用
アドレナリンノルアドレナリン	α1	Gq	血管平滑筋収縮
	α2	Gi	中枢交感神経抑制、インスリン放出抑制
	β1	Gs	心拍数増加、収縮力増加、レニン放出、脂肪分解
	β2		骨格筋筋弛緩、内臓平滑筋弛緩、気道平滑筋弛緩、グリコーゲン放出
	β3		肥満細胞脂質分解亢進
アセチルコリン	M1	Gq	中枢神経
	M2	Gi	心拍数低下
	M3	Gq	外分泌腺分泌亢進
ドーパミン	D1	Gs	腎臓平滑筋弛緩
ドーパミン	D2	Gi	神経伝達物質放出を調節
ヒスタミン	H1	Gq	鼻、器官粘膜分泌、細気管支収縮、かゆみ、痛み
ヒスタミン	H2	Gs	胃酸分泌
バソプレシン	V1	Gq	血管平滑筋収縮
バソプレシン	V2	Gs	腎集合管で水の透過性亢進