ビタミンA貯蔵細胞
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- the 1st letter of the Roman alphabet (同)a
- the blood group whose red cells carry the A antigen (同)type_A, group A
- any of a group of organic substances essential in small quantities to normal metabolism
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- answer / ampere
- 『ビタミン』,栄養素(身体の喜常な機能を維持するために少量ながら必要な有機化合物)
- arsenicの化学記号
UpToDate Contents
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English Journal
- Cellular basis of hepatic fibrosis and its role in inflammation and cancer .
- Kocabayoglu P, Friedman SL.SourceBox 1123, Mount Sinai School of Medicine, 1425 Madison Ave., Room 1170C, New York, NY 10029, USA.
- Frontiers in bioscience (Scholar edition).Front Biosci (Schol Ed).2013 Jan 1;5:217-30.
- Multiple etiologies of liver injury can lead to fibrosis, which results from an imbalance between production and resorption of extracellular matrix. Hepatic stellate cells (HSCs), resident vitamin A storing cells, play a vital role in the response to injury. Upon activation, HSCs orchestrate the res
- PMID 23277047
- Accumulation of vitamin A in the hepatic stellate cell of arctic top predators.
- Senoo H, Imai K, Mezaki Y, Miura M, Morii M, Fujiwara M, Blomhoff R.SourceDepartment of Cell Biology and Morphology, Akita University Graduate School of Medicine, Akita 010-8543, Japan. senoo@gipc.akita-u.ac.jp
- Anatomical record (Hoboken, N.J. : 2007).Anat Rec (Hoboken).2012 Oct;295(10):1660-8. doi: 10.1002/ar.22555. Epub 2012 Aug 21.
- We performed a systematic characterization of the hepatic vitamin A storage in mammals and birds of the Svalbard archipelago and Greenland. The liver of top predators, including polar bear, arctic fox, bearded seal, and glaucous gull, contained about 10-20 times more vitamin A than the liver of all
- PMID 22907891
- Recombinant fusion protein of albumin-retinol binding protein inactivates stellate cells.
- Choi S, Park S, Kim S, Lim C, Kim J, Cha DR, Oh J.SourceLaboratory of Cellular Oncology, Korea University Graduate School of Medicine, Ansan, Gyeonggi do 425-707, Republic of Korea.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2012 Feb 3;418(1):191-7. doi: 10.1016/j.bbrc.2012.01.012. Epub 2012 Jan 12.
- Quiescent pancreatic- (PSCs) and hepatic- (HSCs) stellate cells store vitamin A (retinol) in lipid droplets via retinol binding protein (RBP) receptor and, when activated by profibrogenic stimuli, they transform into myofibroblast-like cells which play a key role in the fibrogenesis. Despite extensi
- PMID 22266308
Japanese Journal
- 肝臓星細胞によるビタミンAの代謝・貯蔵メカニズムとその意義(若手シンポジウム「ビタミン基礎研究の進展を担う若手研究者たち」,<特集>ビタミン基礎研究の進展を担う若手研究者たち(第64回大会若手シンポジウム))
- 目崎 喜弘
- ビタミン 87(1), 33-37, 2013-01-25
- … Hepatic stellate cells (HSCs), which are also known as vitamin A-storing cells, reside in a space between hepatocytes and liver sinusoids. … Two proteins, cellular retinol-binding protein (CRBP) and lecithin:retinol acyltransferase (LRAT), are known to play an important role in vitamin A storage in HSCs, because retinol bound to CRBP is a good substrate for LRAT. …
- NAID 110009578810
- 妹尾 春樹,目崎 喜弘,三浦 光隆 [他],森井 真也子,今井 克幸,藤原 睦憲
- ビタミン 86(7), 381-389, 2012-07-25
- … Hepatic stellate cells (HSCs) exist in the space between parenchymal cells and sinusoidal endothelial cells, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. … HSCs play pivotal roles in regulation of vitamin A homeostasis. … The top predators in the Arctic possessed about 10-20 times more vitamin A than all other arctic animals studied as well as their genetically related continental top predators. …
- NAID 110009480122
- 妹尾 春樹,吉川 究,三浦 光隆 [他],森井 真也子,目崎 喜弘
- ビタミン 84(1), 7-16, 2010-01-25
- … Vitamin A-storing cells in the liver (also called as hepatic stellate cells, lipocytes, interstitial cells, fat-storing cells, or Ito cells) exist in the space between parenchymal cells and liver sinusoidal endothelial cells of the hepatic lobule, and store 50-80% of vitamin A in the whole body as retinyl palmitate in lipid droplets in the cytoplasm. …
- NAID 110007521141
Related Links
- 1. Cell Biol Int. 2010 Dec;34(12):1247-72. doi: 10.1042/CBI20100321. Hepatic stellate cell (vitamin A-storing cell) and its relative--past, present and future. Senoo H(1), Yoshikawa K, Morii M, Miura M, Imai K, Mezaki Y. ...
- 1. Vitam Horm. 2007;75:131-59. Vitamin A-storing cells (stellate cells). Senoo H, Kojima N, Sato M. Hepatic stellate cells (HSCs; also called as vitamin A-storing cells, lipocytes, interstitial cells, fat-storing cells, Ito ...
★リンクテーブル★
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- 英
- stellate cell
- 同
- 脂肪摂取細胞 fat-storing cells、伊東細胞 Ito cell、肝星細胞 hepatic stellate cell、介在細胞 interstitial cell、類洞周囲脂質細胞 perisinusoidal lipocyte、リポサイト lipocyte、ビタミンA貯蔵細胞 vitamin A storing cell
- 関
- ディッセ腔、肝実質細胞、クッパー細胞、類洞周囲腔
[show details]
概念
- 肝臓のディッセ腔に局在(肝臓実質細胞と類洞内皮細胞の間)
機能
- ビタミンAの貯蔵：ビタミンAの恒常性に関与
- 線維化への関与：肝硬変などで線維芽細胞・筋線維芽細胞のような細胞に変化してコラーゲンなどの細胞外基質を分泌
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- 英
- vitamin A storing cell
- 関
- 伊東細胞
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- 関
- adenoviral、adenovirus
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細胞