- 関
- type I restriction endonuclease、type I site-specific deoxyribonuclease
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- the act of keeping something within specified bounds (by force if necessary); "the restriction of the infection to a focal area" (同)confinement
- a principle that limits the extent of something; "I am willing to accept certain restrictions on my movements" (同)limitation
- the 9th letter of the Roman alphabet (同)i
- any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
- writing done with a typewriter (同)typewriting
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- (…を)『制限』(『限定』)『すること』《+『of』+『名』》,制限(限定)されていること / 〈C〉(…に対する)制限事項,制約《+『on』(『against』)+『名』》
- 『私は』私が
- iodineの化学記号
- 酵素
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/05/20 14:34:01」(JST)
[Wiki en表示]
| Type I site-specific deoxyribonuclease |
| Identifiers |
| EC number |
3.1.21.3 |
| CAS number |
37263-09-5 |
| Databases |
| IntEnz |
IntEnz view |
| BRENDA |
BRENDA entry |
| ExPASy |
NiceZyme view |
| KEGG |
KEGG entry |
| MetaCyc |
metabolic pathway |
| PRIAM |
profile |
| PDB structures |
RCSB PDB PDBe PDBsum |
| Search |
| PMC |
articles |
| PubMed |
articles |
| NCBI |
proteins |
|
Type I site-specific deoxyribonuclease (EC 3.1.21.3, type I restriction enzyme, deoxyribonuclease (ATP- and S-adenosyl-L-methionine-dependent), restriction-modification system, deoxyribonuclease (adenosine triphosphate-hydrolyzing), adenosine triphosphate-dependent deoxyribonuclease, ATP-dependent DNase, type 1 site-specific deoxyribonuclease) is an enzyme.[1] This enzyme catalyses the following chemical reaction
- Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolysed
They have an absolute requirement for ATP (or dATP) and S-adenosyl-L-methionine.
References
- ^ Roberts, R.J. (1990). "Restriction enzymes and their isoschizomers". Nucleic Acids Res. 18: 2331–2365. doi:10.1093/nar/18.suppl.2331. PMID 2159140.
See also
External links
- Type I site-specific deoxyribonuclease at the US National Library of Medicine Medical Subject Headings (MeSH)
|
Hydrolase: esterases (EC 3.1)
|
|
3.1.1: Carboxylic
ester hydrolases |
- Cholinesterase
- Acetylcholinesterase
- Butyrylcholinesterase
- Pectinesterase
- 6-phosphogluconolactonase
- PAF acetylhydrolase
- Lipase
- Bile salt-dependent
- Gastric/Lingual
- Pancreatic
- Lysosomal
- Hormone-sensitive
- Endothelial
- Hepatic
- Lipoprotein
- Monoacylglycerol
- Diacylglycerol
|
|
| 3.1.2: Thioesterase |
- Palmitoyl protein thioesterase
- Ubiquitin carboxy-terminal hydrolase L1
- 4-hydroxybenzoyl-CoA thioesterase
|
|
| 3.1.3: Phosphatase |
- Alkaline phosphatase
- Acid phosphatase (Prostatic)/Tartrate-resistant acid phosphatase/Purple acid phosphatases
- Nucleotidase
- Glucose 6-phosphatase
- Fructose 1,6-bisphosphatase
- Protein phosphatase
- OCRL
- Pyruvate dehydrogenase phosphatase
- Fructose 6-P,2-kinase:fructose 2,6-bisphosphatase
- PTEN
- Phytase
- Inositol-phosphate phosphatase
- Protein phosphatase: Protein tyrosine phosphatase
- Protein serine/threonine phosphatase
- Dual-specificity phosphatase
|
|
| 3.1.4: Phosphodiesterase |
- Autotaxin
- Phospholipase
- Sphingomyelin phosphodiesterase
- PDE1
- PDE2
- PDE3
- PDE4A/PDE4B
- PDE5
- Lecithinase (Clostridium perfringens alpha toxin)
- Cyclic nucleotide phosphodiesterase
|
|
| 3.1.6: Sulfatase |
- arylsulfatase
- Arylsulfatase A
- Arylsulfatase B
- Arylsulfatase E
- Steroid sulfatase
- Galactosamine-6 sulfatase
- Iduronate-2-sulfatase
- N-acetylglucosamine-6-sulfatase
|
|
Nuclease (includes
deoxyribonuclease and
ribonuclease) |
| 3.1.11-16: Exonuclease |
| Exodeoxyribonuclease |
|
|
| Exoribonuclease |
|
|
|
| 3.1.21-31: Endonuclease |
| Endodeoxyribonuclease |
- Deoxyribonuclease I
- Deoxyribonuclease II
- Deoxyribonuclease IV
- Restriction enzyme
- UvrABC endonuclease
|
|
| Endoribonuclease |
- RNase III
- RNase H
- RNase P
- RNase A
- RNase T1
- RNA-induced silencing complex
|
|
| either deoxy- or ribo- |
- Aspergillus nuclease S1
- Micrococcal nuclease
|
|
|
|
|
Enzymes
|
|
| Activity |
- Active site
- Binding site
- Catalytic triad
- Oxyanion hole
- Enzyme promiscuity
- Catalytically perfect enzyme
- Coenzyme
- Cofactor
- Enzyme catalysis
- Enzyme kinetics
- Lineweaver–Burk plot
- Michaelis–Menten kinetics
|
|
| Regulation |
- Allosteric regulation
- Cooperativity
- Enzyme inhibitor
|
|
| Classification |
- EC number
- Enzyme superfamily
- Enzyme family
- List of enzymes
|
|
| Types |
- EC1 Oxidoreductases(list)
- EC2 Transferases(list)
- EC3 Hydrolases(list)
- EC4 Lyases(list)
- EC5 Isomerases(list)
- EC6 Ligases(list)
|
|
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
English Journal
- ClpXP protease targets long-lived DNA translocation states of a helicase-like motor to cause restriction alleviation.
- Simons M1, Diffin FM1, Szczelkun MD2.
- Nucleic acids research.Nucleic Acids Res.2014 Oct 29;42(19):12082-91. doi: 10.1093/nar/gku851. Epub 2014 Sep 26.
- We investigated how Escherichia coli ClpXP targets the helicase-nuclease (HsdR) subunit of the bacterial Type I restriction-modification enzyme EcoKI during restriction alleviation (RA). RA is a temporary reduction in endonuclease activity that occurs when Type I enzymes bind unmodified recognition
- PMID 25260590
- Interdomain communication in the endonuclease/motor subunit of type I restriction-modification enzyme EcoR124I.
- Sinha D1, Shamayeva K, Ramasubramani V, Řeha D, Bialevich V, Khabiri M, Guzanová A, Milbar N, Weiserová M, Csefalvay E, Carey J, Ettrich R.
- Journal of molecular modeling.J Mol Model.2014 Jul;20(7):2334. doi: 10.1007/s00894-014-2334-1. Epub 2014 Jun 28.
- Restriction-modification systems protect bacteria from foreign DNA. Type I restriction-modification enzymes are multifunctional heteromeric complexes with DNA-cleavage and ATP-dependent DNA translocation activities located on endonuclease/motor subunit HsdR. The recent structure of the first intact
- PMID 24972799
- Cloning, crystallization and preliminary X-ray diffraction analysis of an intact DNA methyltransferase of a type I restriction-modification enzyme from Vibrio vulnificus.
- Huynh Thi Yen L1, Park SY1, Kim JS1.
- Acta crystallographica. Section F, Structural biology communications.Acta Crystallogr F Struct Biol Commun.2014 Apr;70(Pt 4):489-92. doi: 10.1107/S2053230X14004543. Epub 2014 Mar 25.
- Independently of the restriction (HsdR) subunit, the specificity (HsdS) and methylation (HsdM) subunits interact with each other, and function as a methyltransferase in type I restriction-modification systems. A single gene that combines the HsdS and HsdM subunits in Vibrio vulnificus YJ016 was expr
- PMID 24699746
Japanese Journal
- Uranium (U)-Tolerant Bacterial Diversity from U Ore Deposit of Domiasiat in North-East India and Its Prospective Utilisation in Bioremediation
- Kumar Rakshak,Nongkhlaw Macmillan,Acharya Celin,Joshi Santa Ram
- Microbes and Environments 28(1), 33-41, 2013
- … The bacterial community explored at molecular level by amplified ribosomal DNA restriction analysis (ARDRA) resulted in 51 distinct phylotypes. … Overall, 76% of characterized isolates possessed phosphatase enzyme and 53% had PIB-type ATPase genes. … Also, these natural isolates efficient in uranium binding and harbouring phosphatase enzyme and metal-transporting genes could possibly play a vital role in the bioremediation of metal-/radionuclide-contaminated environments. …
- NAID 130001877520
- Molecular Identification of Genotypes of Pilophorus typicus (Heteroptera : Miridae) in Japan using PCR-RFLP Analysis of Mitochondrial DNA
- Ito Katsura,Nishikawa Hiroshi,Shimada Takuji [他],OGAWA Kohei,MINAMIYA Yukio,HAYAKAWA Hiroshi,FUKUDA Tatsuya,ARAKAWA Ryo
- Environment control in biology 47(4), 191-195, 2009-12-30
- … The PCR product of the southern type yielded two DNA bands by the action of the restriction enzyme of <I>Psi</I> … I, whereas that of the northern type gave only a single band on electrophoresis. … Moreover, the PCR-RFLP using samples from many localities revealed that the restriction site of <I>Psi</I> … I is well conserved within each type. …
- NAID 10026429646
- 捕獲グレービーシマウマおよびブラックバック由来ウマヘルペスウイルス1型関連ウイルスの特性(短報)(ウイルス学)
- Borches Kerstin,Bottner Daniel,Lieckfeldt Dietmar [他],ほか6名,FROLICH Kai,KLINGEBORN Berndt,WIDEN Frederik,ALLEN George,LUDWIG Hanns
- The journal of veterinary medical science 68(7), 757-760, 2006-07-25
- 捕獲ブラックバック(Ro-1株)およびグレービーシマウマ(T965株)から分離されたウマヘルペスウイルス1型(EHV-1)関連ウイルスの宿主細胞域はEHV-1やEHV-9と類似していた.制限酵素解析及び系統樹解析によりRo-1とT965は同一であり,EHV-9よりもEHV-1により近縁であることが確認された.EHV-1との相違の第1としてRo-1およびT965株gB蛋白質における2カ所のアミノ酸置 …
- NAID 110004763190
Related Links
- In 1970, Hamilton O. Smith, Thomas Kelly and Kent Welcox isolated and characterized the first type II restriction enzyme, HindII, from the bacterium Haemophilus influenzae. [18] [19] This type of restriction enzymes is more It [] ...
- Although DNA-recognition sequences are among the most important characteristics of restriction enzymes and their corresponding methylases, determination of the recognition sequence of a Type-I restriction enzyme is a ...
★リンクテーブル★
[★]
- 英
- type I restriction enzyme
- 関
- I型部位特異的デオキシリボヌクレアーゼ、I型制限エンドヌクレアーゼ
[★]
I型部位特異的デオキシリボヌクレアーゼ
- 関
- type I restriction endonuclease、type I restriction enzyme
[★]
- 関
- type I restriction enzyme、type I site-specific deoxyribonuclease
[★]
- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
[★]
- 関
- circumscription、confine、confinement、define、definite、definition、limit、limitation、qualify、restrain、restraint、restrict
[★]
[★]
[★]
- 関
- form、mode、pattern、type