- 同
- SRS
WordNet
- not moving quickly; taking a comparatively long time; "a slow walker"; "the slow lane of traffic"; "her steps were slow"; "he was slow in reacting to the news"; "slow but steady growth"
- cause to proceed more slowly; "The illness slowed him down" (同)slow down, slow up
- become slow or slower; "Production slowed" (同)slow down, slow up, slack, slacken
- (used of timepieces) indicating a time earlier than the correct time; "the clock is slow"
- at a slow tempo; "the band played a slow waltz"
- material of a particular kind or constitution; "the immune response recognizes invading substances"
- a particular kind or species of matter with uniform properties; "shigella is one of the most toxic substances known to man"
- the real physical matter of which a person or thing consists; "DNA is the substance of our genes"
PrepTutorEJDIC
- (速度・動作などが)『遅い』,のろい / 《補語または名詞の後にのみ用いて》(時計などが)『遅れている』 / 『ゆったりした』,あわてない / (人が)理解の遅い,頭の鈍い / (生活・パーティーなどが)『活気のない』,おもしろくない / 遅く,ゆっくり(slowly) / 『遅くなる』,速度を落とす《+『down』(『up』)》 / …‘を'『遅くする』,‘の'速度を落とす《+『名』+『down』(『up』),+『down』(『up』)+『名』》
- 〈U〉『物質』,物 / 〈U〉《the~》(…の)『趣旨』,本音《+of+名》 / 〈U〉(スープなどの)濃さ,こく,中身[の詰まっていること] / 〈U〉『実質』,実 / 〈U〉《古》財産,資産
UpToDate Contents
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English Journal
- [Leukotrien antagonists in the treatment of allergic rhinitis and comorbidities].
- Sacre Hazouri JA1.
- Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993).Rev Alerg Mex.2008 Jul-Aug;55(4):164-75.
- Leukotrienes comprise a family of products of the 5-lipoxigenase pathway of arachidonic acid metabolism. The cysteinil leukotrienes C4, D4 and E4 account for the biologic activity that was previously termed "slow-reacting substance of anaphylaxis". The proinflammatory effects of cysteinil leukotrien
- PMID 19058495
- The cysteinyl leukotrienes: where do they come from? What are they? Where are they going?
- Austen KF1.
- Nature immunology.Nat Immunol.2008 Feb;9(2):113-5. doi: 10.1038/ni0208-113.
- Cysteinyl leukotrienes are established mediators of bronchial asthma and have agonist roles analogous to those of histamine in allergic rhinitis. We now know that the substance originally termed slow-reacting substance of anaphylaxis was composed of three cysteinyl leukotrienes that act in the infla
- PMID 18204420
- Crystal structure of a human membrane protein involved in cysteinyl leukotriene biosynthesis.
- Ago H1, Kanaoka Y, Irikura D, Lam BK, Shimamura T, Austen KF, Miyano M.
- Nature.Nature.2007 Aug 2;448(7153):609-12. Epub 2007 Jul 15.
- The cysteinyl leukotrienes, namely leukotriene (LT)C4 and its metabolites LTD4 and LTE4, the components of slow-reacting substance of anaphylaxis, are lipid mediators of smooth muscle constriction and inflammation, particularly implicated in bronchial asthma. LTC4 synthase (LTC4S), the pivotal enzym
- PMID 17632548
Japanese Journal
- 阿部 正義,吉本 谷博
- 日本薬理学雑誌 : FOLIA PHARMACOLOGICA JAPONICA 124(4), 415-425, 2004-10-01
- … ロイコトリエン・リポキシゲナーゼ系に関連した薬の中で最初に臨床的に確かな評価を得たのは,構造式の決定に長年の研究を要したslow reacting substance of anaphylaxis(SRS-A)を抑制するものであった.最初に抗喘息薬として登場したのは5-リポキシゲナーゼ阻害薬であったが,次に開発されたcysteinyl-leukotriene type 1 receptor(cysLT1R)拮抗薬が5-リポキシゲナーゼ阻害薬と同等以上の効果 …
- NAID 10025739505
- トロンボキサンA2受容体拮抗薬 : セラトロダストの創製研究
- 寺尾 秦次,白石 充,松本 辰美 [他],蘆田 康子
- 藥學雜誌 119(5), 377-390, 1999-05-01
- … We were interested in RCS (rabbit aorta contracting substance) and SRS-A(slow reacting substance of anaphylaxis) and their involvement in human bronchial asthma. …
- NAID 110003648745
- Synthesis and Structure-Activity Relationships of Antiallergic N-[4-[4-(1H-Indol-3-yl)piperidinoalkyl]-2-thiazolyl]alkanamides Possessing Both Antihistaminic and Anti Slow-Reacting Substance (SRS) Activites
- 重永 信次,真鍋 孝司,松田 博,藤井 隆,松尾 昌昭
- Chemical & pharmaceutical bulletin 42(9), 1822-1827, 1994-09-15
- … A series of N-[4-[4-(1H-indol-3-yl)piperidinoalkyl]-2-thiazolyl]alkanamide derivatives were synthesized and tested for in vivo antianaphylactic activity and in vitro anti slow-reacting substance (SRS) activity. …
- NAID 110003631242
Related Links
- substance /sub·stance/ (sub´stans) 1. matter with a particular set of characteristics. 2. material constituting an organ or body. 3. psychoactive s. black substance substantia nigra. controlled substance any drug regulated under the ...
- Feldberg W, Kellaway CH. Liberation of histamine and formation of lysocithin-like substances by cobra venom. J Physiol. 1938 Nov 14; 94 (2):187–226. [PMC free article] [PubMed] Feldberg W, Kellaway CH. Liberation of histamine ...
★リンクテーブル★
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- 関
- 遅発反応性物質 slow-reacting substance slow-reacting substance of anaphylaxis
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アナフィラキシー遅延反応物質, SRS-A
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- (比較級slower-最上級slowest)緩徐な、遅い、ゆっくりとした、緩慢な
- 関
- gradual、gradually、late、slowly、sluggish
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- 関
- entity、material、matter
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