WordNet

without possessing something at the time it is contractually sold; "he made his fortune by selling short just before the crash"
the location on a baseball field where the shortstop is stationed
low in stature; not tall; "he was short and stocky"; "short in stature"; "a short smokestack"; "a little man" (同)little
lacking foresight or scope; "a short view of the problem"; "shortsighted policies"; "shortsighted critics derided the plan"; "myopic thinking" (同)shortsighted, unforesightful, myopic
at a disadvantage; "I was caught short" (同)unawares
(primarily spatial sense) having little length or lacking in length; "short skirts"; "short hair"; "the board was a foot short"; "a short toss"
at some point or distance before a goal is reached; "he fell short of our expectations"
clean across; "the cars axle snapped short"
not holding securities or commodities that one sells in expectation of a fall in prices; "a short sale"; "short in cotton"
of speech sounds or syllables of relatively short duration; "the English vowel sounds in `pat, `pet, `pit, `pot, putt are short"
primarily temporal sense; indicating or being or seeming to be limited in duration; "a short life"; "a short flight"; "a short holiday"; "a short story"; "only a few short months"
so as to interrupt; "She took him up short before he could continue"
tending to crumble or break into flakes due to a large amount of shortening; "shortbread is a short crumbly cookie"; "a short flaky pie crust"
high level of respect gained by impressive development or achievement; "a man of great stature"
(of a standing person) the distance from head to foot (同)height
the act of propping up with shores (同)shoring up, propping up

PrepTutorEJDIC

(長さ・時間・距離などが)『短い』,近い・(人が)『背が低い』・(数量・期間などが)不足の』,乏しい;目標(標準)に達しない・(文などが)『簡潔な』,手短な・『そっけない』,ぞんぞいな,無愛想な・(ケーキなどが)かりかりする,さくさくする・(母音・音節が)短い;(詩の行の母音が)強勢のない・急に,突然・短いもの;欠けているもの・短篇映画(short movie, short subject) ・=short circuit・《複数形で》不足,欠損 / …‘を'短絡させる,ショートさせる / 短絡する,ショートする
『背』(せい),身長(height) / (身体の,また道徳的・知的な)発達,成長,進歩
半ズボン,ショートパンツ / 《おもに米》(男物下着の)パンツ

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/01/07 21:07:50」(JST)

wiki en

Short stature refers to a height of a human being which is below typical. Whether a person is considered short depends on the context. Because of the lack of preciseness, there is often disagreement about the degree of shortness that should be called short.

In a medical context, short stature is typically defined as an adult height that is more than two standard deviations below the mean for age and gender, which corresponds to the shortest 2.3% of individuals.^[1] In developed countries, this typically includes adult men who are shorter than 163 centimetres (5 ft 4 in) tall and adult women who are shorter than 150 centimetres (4 ft 11 in) tall. Again though, when shortness is called "short" is debatable, others would say 170 centimetres (5 ft 7 in) and 157 centimetres (5 ft 2 in) for men and women respectively due to those heights being one standard deviation below the average for each of their genders, while others would say 155 centimetres (5 ft 1 in) for men and 143 centimetres (4 ft 8 in) for women since both heights are three standard deviations below the average for their respective genders. In either of those cases, by comparison, the median or typical adult height in these populations (as the widely abundant statistics from these countries clearly state) is about 170.5 centimetres (5 ft 7.1 in) for men and 160 centimetres (5 ft 3 in) for women.^[2]

Causes

Shortness in children and young adults nearly always results from below-average growth in childhood, while shortness in older adults usually results from loss of height due to kyphosis of the spine or collapsed vertebrae from osteoporosis.

From a medical perspective, severe shortness can be a variation of normal, resulting from the interplay of multiple familial genes. It can also be due to one or more of many abnormal conditions, such as chronic (prolonged) hormone deficiency, malnutrition, disease of a major organ system, mistreatment, treatment with certain drugs, chromosomal deletions, inherited diseases, birth defect syndromes, bone structures fusing earlier than intended or many other causes.

Human Growth Hormone (HGH) deficiency may occur at any time during infancy or childhood, with the most obvious sign being a noticeable slowing of growth. The deficiency may be genetic.

Among children without growth hormone deficiency, short stature may be caused by Turner syndrome, chronic renal insufficiency, being small for gestational age at birth, Prader–Willi syndrome, or other conditions. When the cause is unknown, it is called idiopathic short stature.^[3]

Short stature can also be caused by the bone plates fusing at an earlier age than normal, therefore stunting growth. Normally, your bone age is the same as your biological age but for some people, it is older. For many people with advanced bone ages, they hit a growth spurt early on which propels them to average height but stop growing at an earlier age. However in some cases, people who are naturally shorter combined with their advanced bone age, end up being even shorter than the height they normally would have been because of their stunted growth.

Treatment

The decision to treat is based on a belief that the child will be disabled by being extremely short as an adult, so that the risks of treatment (including sudden death^[3]) will outweigh the risks of not treating the symptom of short stature. Although short children commonly report being teased about their height, most adults who are very short are not physically or psychologically disabled by their height.^[3] However, there is some evidence to suggest that there is an inverse linear relationship with height and with risk of suicide.^[4]

Treatment is expensive and requires many years of injections with human growth hormones. The result depends on the cause, but is typically an increase in final height of about 5 to 10 centimetres (2.0 to 3.9 in) taller than predicted.^[3] Thus, treatment takes a child who is expected to be much shorter than a typical adult and produces an adult who is still obviously shorter than average. For example, several years of successful treatment in a girl who is predicted to be 145 centimetres (4 ft 9 in) as an adult may result in her being 150 centimetres (4 ft 11 in) instead.

Increasing final height in children with short stature may be beneficial and could enhance health-related quality of life outcomes, barring troublesome side effects and excessive cost of treatments.^[5]

Cost of treatment

The cost of treatment depends on the amount of growth hormone given, which in turn depends on the child's weight and age. One year's worth of drugs normally costs about US $20,000 for a small child and over $50,000 for a teenager.^[3] These drugs are normally taken for five or more years.

Cultural issues

From a social perspective shortness can be a problem independently of the cause. In many societies there are advantages associated with taller stature and disadvantages associated with shorter stature, and vice versa.

Pharmaceutical companies Genentech and Eli Lilly, makers of human growth hormone, have worked to medicalize short stature by convincing the public that short stature is a disease rather than a natural variation in human height.^[6] Limiting sales of the hormone to children diagnosed with growth hormone deficiency, rather than being short for any reason, limited their sales market.^[6] Expanding it to all children whose height was below the third percentile would create 90,000 new customers and US $10 billion in revenue.^[7] In the early 1990s, they paid two US charities, the Human Growth Foundation and the MAGIC Foundation, to measure the height of thousands of American children in schools and public places, and to send letters urging medical consultations for children whose height was deemed low.^[6] Parents and schools were not told that the charities were being paid by the drug companies to do this.^[6]^[7]

Paired with a campaign to advertise the hormone to physicians, the campaign was successful, and tens of thousands of children began receiving HGH.^[7] About half of them do not have growth hormone deficiency, and consequently benefited very little, if at all, from the hormone injections.^[7] Criticism of the universal screening program eventually resulted in its end.^[7]

History

During WWI in Britain, the minimum height for soldiers was 5 feet 3 inches (160 cm). Thus thousands of men under this height were denied the ability to fight in the war. As a result of pressure to allow them entry, special "Bantam Battalions" were created composed of men who were 5 feet 0 inches (152 cm) to 5 feet 3 inches (160 cm). By the end of the war there were 29 Bantam Battalions of about 1,000 men each. Officers were of "normal" size.^[8]

References

^ Pedicelli S, Peschiaroli E, Violi E, Cianfarani S (2009). "Controversies in the definition and treatment of idiopathic short stature (ISS)". J Clin Res Pediatr Endocrinol 1 (3): 105–15. doi:10.4008/jcrpe.v1i3.53. PMC 3005647. PMID 21274395.
^ Becker, Kenneth L., ed. (2001). "Growth and Development in the Normal Infant and Child, Table 7.1". Principles and Practice of Endocrinology and Metabolism (3 ed.). Philadelphia, Pa.: Lippincott, Williams & Wilkins. p. 69. ISBN 9780781717502.
^ ^a ^b ^c ^d ^e Allen DB (July 2006). "Growth hormone therapy for short stature: is the benefit worth the burden?". Pediatrics 118 (1): 343–8. doi:10.1542/peds.2006-0329. PMID 16818584.
^ "Psychiatry Online Strong Inverse Association Between Height and Suicide in a Large Cohort of Swedish Men: Evidence of Early Life Origins of Suicidal Behavior?". Retrieved 2014-02-25.
^ "Height and Health-related Quality of Life".
^ ^a ^b ^c ^d Brody, Howard (2007). Hooked: ethics, the medical profession, and the pharmaceutical industry. Lanham, Md: Rowman & Littlefield. p. 236. ISBN 0-7425-5218-7.
^ ^a ^b ^c ^d ^e Valenstein, Elliot S. (2002). Blaming the Brain : The Truth About Drugs and Mental Health. New York: Free Press. pp. 173–174. ISBN 0-7432-3787-0.
^ Tom de Castella (8 February 2015). "Bantams: The army units for those under 5ft 3in". BBC News Magazine. Retrieved February 9, 2015.

UpToDate Contents

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1. 低身長の小児や青年への診断的アプローチ diagnostic approach to children and adolescents with short stature
2. 低身長の原因 causes of short stature
3. 特発性低身長に対する成長ホルモン治療 growth hormone treatment for idiopathic short stature
4. 小児における成長ホルモン欠乏症の診断 diagnosis of growth hormone deficiency in children
5. Dyskeratosis congenita and other short telomere syndromes

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