- 関
- pirenzepine、pirenzepine hydrochloride hydrate
WordNet
- a complex consisting of an organic base in association with hydrogen chloride
UpToDate Contents
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English Journal
- Muscarinic receptor control of pyramidal neuron membrane potential in the medial prefrontal cortex (mPFC) in rats.
- Kurowski P1, Gawlak M1, Szulczyk P2.
- Neuroscience.Neuroscience.2015 Sep 10;303:474-88. doi: 10.1016/j.neuroscience.2015.07.023. Epub 2015 Jul 14.
- PMID 26186898
- Precise, fast, and flexible determination of protein interactions by affinity capillary electrophoresis: part 1: performance.
- Redweik S1, Xu Y, Wätzig H.
- Electrophoresis.Electrophoresis.2012 Nov;33(22):3316-22. doi: 10.1002/elps.201200181. Epub 2012 Sep 12.
- PMID 22968653
- Characterization of 5-hydroxytryptamine-induced contraction and acetylcholine-induced relaxation in isolated chicken basilar artery.
- Matsumoto F1, Watanabe Y, Obi T, Islam MZ, Yamazaki-Himeno E, Shiraishi M, Miyamoto A.
- Poultry science.Poult Sci.2012 May;91(5):1158-64. doi: 10.3382/ps.2011-01945.
- PMID 22499874
Japanese Journal
- Involvement of the Cholinergic Pathway in the Pathogenesis of Pituitary Cushing's Syndrome.
- Activation of Cerebral Function by CS-932, a Functionally Selective M_1 Partial Agonist : Neurochemical Characterization and Pharmacological Studies
- The Japanese journal of pharmacology 84(3), 266-280, 2000-11-01
- NAID 10008186089
- 尿失禁・頻尿改善薬Propiverine hydrochlorideの組織ムスカリン受容体への結合親和性および唾液分泌抑制に関する研究
Related Links
- View and buy high purity Pirenzepine dihydrochloride from Tocris Bioscience, the leading worldwide supplier of high performance life science reagents ... The technical data provided above is for guidance only. For batch specific data ...
- Anticholinergics/Antispasmodics (Systemic) This monograph includes information on the following: 1) Anisotropine † 2) Atropine 3) Belladonna † 4) Clidinium † 5) Dicyclomine 6) Glycopyrrolate 7) Homatropine † 8) Hyoscyamine 9 ...
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★リンクテーブル★
[★]
- 英
- pirenzepine
- 化
- 塩酸ピレンゼピン pirenzepine hydrochloride
- 商
- ガストシオン、ガストロゼピン、ガタンプル、カロデリン、ストマゼピン、ピレンゼール、ピロデイン、ピン、ランクリック
- 関
- ムスカリン性受容体、テレンゼピン
- 消化性潰瘍用剤
- → 血液脳関門を通過しないので、中枢作用がない
- 消化管、尿路に対する作用が無く、散瞳、視力障害、循環器に対する作用もない (SPC.162)
- M1受容体特異的に作用する
薬理作用
- 胃粘膜壁細胞のムスカリン受容体に選択的に作用し胃酸分泌を抑制
- 迷走神経の胃酸分泌機能を特異的に抑制
[★]
- 関
- pirenzepine、pirenzepine hydrochloride
[★]
塩酸塩、ハイドロクロライド